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UID:news1457@biomedizin.unibas.ch
DTSTAMP;TZID=Europe/Zurich:20250317T215639
DTSTART;TZID=Europe/Zurich:20250318T160000
SUMMARY:Journal Club: American Society of Transplantation - Speaker Carolin
 e A. Hillenbrand (Hirsch Lab)
DESCRIPTION:Join us to discuss the article: BK Polyomavirus (BKPyV) Serotyp
 e-Specific Antibody Responses in Blood Donors and Kidney Transplant Recipi
 ents with and without new-onset BKPyV-DNAemia: A Swiss Transplant Cohort S
 tudy\\r\\n11.00am – 12.00pm ET\\r\\nREGISTER [https://us06web.zoom.us/we
 binar/register/WN_xwibcOUMQ4OqWjBV_IYfkg#/registration] for Webinar\\r\\n
 \\r\\nIn this featured American Journal of Transplantation (AJT) article: 
 BK polyomavirus (BKPyV) causes premature renal failure in 10% to 30% of ki
 dney transplant recipients (KTRs). Current guidelines recommend screening 
 for new-onset BKPyV-DNAemia/nephropathy and reducing immunosuppression to 
 regain BKPyV-specific immune control. Because BKPyV encompasses 4 major ge
 notype (gt)-encoded serotypes (st1\,-2\,-3\,-4)\, st-specific antibodies m
 ay inform the risk and course of BKPyV-DNAemia/nephropathy. [The authors] 
 analyzed plasma from 399 blood donors (BDs) and 428 KTRs (134 KTR-cases wi
 th BKPyV-DNAemia\, 294 KTR-controls)... [and found] BKPyV st-specific anti
 body levels at transplantation might reflect gt/st-BKPyV-specific immunity
  clearing or preventing BKPyV-DNAemia in KTR-cases or KTR-controls\, respe
 ctively. Accordingly\, active or passive immunization may be most efficien
 t pretransplant or early posttransplant. Read more [https://asttransplant.
 acemlna.com/lt.php?x=3DZy~GE7J6Kf78360_66VRRs1qEpvgP1ketgk5LHVaWZ5KCr-0y.0
 OJv2HBzidTxk_YzbHPDIXKf]\\r\\nThis AST Journal Club Series webinar is host
 ed by AST's Infectious Disease Community of Practice (IDCOP). All AST Jour
 nal Clubs are free but registration is required to attend live. To learn m
 ore about the American Journal of Transplantation (AJT)\, visit www.amjtr
 ansplant.org [https://asttransplant.acemlna.com/lt.php?x=3DZy~GE7J6Kf78360
 _66VRRs1qEpvgP1ketgk5LHVaWZ5KCr-0y.0OJv2HBzidTxk_YzbHPDIXKh].\\r\\n All AS
 T Journal Clubs are free\, but registration [https://asttransplant.acemln
 a.com/lt.php?x=3DZy~GE7J6Kf78360_66VRRs1qEpvgP1ketgk5LHVaWZ5KCr-0y.0OJv2HB
 zidTxk_YzbHPDIXKg] is required to attend live. Can't make the live Journa
 l Club? Register now\, and you'll be notified when the archive is availabl
 e.
X-ALT-DESC:<p>Join us to discuss the article: <strong>BK Polyomavirus (BKPy
 V) Serotype-Specific Antibody Responses in Blood Donors and Kidney Transpl
 ant Recipients with and without new-onset BKPyV-DNAemia: A Swiss Transplan
 t Cohort Study</strong></p>\n<p><strong>11.00am – 12.00pm ET</strong></p
 >\n<p><strong><a href="https://us06web.zoom.us/webinar/register/WN_xwibcOU
 MQ4OqWjBV_IYfkg#/registration">REGISTER</a>&nbsp\;for Webinar</strong></p>
 \n\n<p>In this featured American Journal of Transplantation (AJT) article:
 <br /> BK polyomavirus (BKPyV) causes premature renal failure in 10% to 30
 % of kidney transplant recipients (KTRs). Current guidelines recommend scr
 eening for new-onset BKPyV-DNAemia/nephropathy and reducing immunosuppress
 ion to regain BKPyV-specific immune control. Because BKPyV encompasses 4 m
 ajor genotype (gt)-encoded serotypes (st1\,-2\,-3\,-4)\, st-specific antib
 odies may inform the risk and course of BKPyV-DNAemia/nephropathy. [The au
 thors] analyzed plasma from 399 blood donors (BDs) and 428 KTRs (134 KTR-c
 ases with BKPyV-DNAemia\, 294 KTR-controls)... [and found] BKPyV st-specif
 ic antibody levels at transplantation might reflect gt/st-BKPyV-specific i
 mmunity clearing or preventing BKPyV-DNAemia in KTR-cases or KTR-controls\
 , respectively. Accordingly\, active or passive immunization may be most e
 fficient pretransplant or early posttransplant. <a href="https://asttransp
 lant.acemlna.com/lt.php?x=3DZy~GE7J6Kf78360_66VRRs1qEpvgP1ketgk5LHVaWZ5KCr
 -0y.0OJv2HBzidTxk_YzbHPDIXKf">Read more</a></p>\n<p>This AST Journal Club 
 Series webinar is hosted by AST's Infectious Disease Community of Practice
  (IDCOP). All AST Journal Clubs are free but registration is required to a
 ttend live. To learn more about the American Journal of Transplantation (A
 JT)\, visit&nbsp\;<a href="https://asttransplant.acemlna.com/lt.php?x=3DZy
 ~GE7J6Kf78360_66VRRs1qEpvgP1ketgk5LHVaWZ5KCr-0y.0OJv2HBzidTxk_YzbHPDIXKh" 
 title="https://asttransplant.acemlna.com/lt.php?x=3DZy~GE7J6Kf78360_66VRRs
 1qEpvgP1ketgk5LHVaWZ5KCr-0y.0OJv2HBzidTxk_YzbHPDIXKh">www.amjtransplant.or
 g</a>.</p>\n<p><br /> All AST Journal Clubs are free\, but&nbsp\;<a href="
 https://asttransplant.acemlna.com/lt.php?x=3DZy~GE7J6Kf78360_66VRRs1qEpvgP
 1ketgk5LHVaWZ5KCr-0y.0OJv2HBzidTxk_YzbHPDIXKg" title="https://asttransplan
 t.acemlna.com/lt.php?x=3DZy~GE7J6Kf78360_66VRRs1qEpvgP1ketgk5LHVaWZ5KCr-0y
 .0OJv2HBzidTxk_YzbHPDIXKg" target="_blank">registration</a>&nbsp\;is requi
 red to attend live. Can't make the live Journal Club? Register now\, and y
 ou'll be notified when the archive is available.</p>
DTEND;TZID=Europe/Zurich:20250318T170000
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END:VCALENDAR
