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Takahashi, A., Lee, R., Iwasato, T., Itohara, S., Arima, H., Bettler, B., Miczek, K., and Koide, T. (2015). Glutamate input in the dorsal raphe nucleus as a determinant of escalated aggression in male mice. J. Neurosci. 35(16), 6452-6463.

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Martin C.B., Gassmann, M., Chevarin C., Hamon, M., Rudolph, U., Bettler, B., Lanfumey, L, Mongeau, R. (2014). Effect of genetic and pharmacological blockade of GABA receptors on the 5-HT_2C receptor function during stress. J. Neurochem. 131(5), 566-572.

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Adelfinger, L., Turecek, R., Ivankova, K., Jensen, A.A., Moss, S.J., Gassmann, M., Bettler, B. (2014). GABA_B receptor phosphorylation regulates KCTD12-induced K⁺ current desensitization. Biochemical Pharmacology 91, 369-379.

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Giachino, C., Barz, M., Tchorz, JS., Tome, M., Gassmann, M., Bischofberger, J., Bettler, B. and Taylor, V. (2014). GABA suppresses neurogenesis in the adult hippocampus through GABA_B receptors. Development 141(1), 83-90.

Ito, Y., Banno, R., Shibata, M., Adachi,K., Hagimoto, S., Hagiwara, D., Ozawa, Y., Goto, M., Suga,H., Sugimura, Y., Bettler, B., Oiso, Y., and Arima, H. (2013). GABA type-B receptor signaling in proopiomelanocortin neurons protects against obesity, insulin resistance and hypothalamic inflammation in male mice on a high fat diet. J. Neurosci. 33(43), 17166-73.

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Metz, M., Gassmann, M., Fakler, B., Schaeren-Wiemers, N. and Bettler, B. (2011). Distribution of the auxiliary GABA_B receptor subunits KCTD8, 12, 12b and 16 in the mouse brain. J. Comp. Neurol. 519(8), 1435-1454.

Comps-Agrar, L., Kniazeff, J., Norskov-Lauritsen, L., Maurel, D., Gassmann, M, Gregor, N., Prezeau, L., Bettler, B., Durroux, T., Trinquet, E and J.-P. Pin. (2011). The oligomeric state sets GABA_B receptor signaling efficacy. EMBO J. 30(12), 2336-2349.

Revel, F. G., Moreau, J.-L., Gainetdinov, R. R., Bradaia, A., Sotnikova, T. D., Mory, R., Durkin, S., Groebke-Zbinden, K., Norcross, R. D., Meyer, C. A., Metzler, V., Chaboz, S., Ozmen, L., Trube, G., Pouzet, B., Bettler , B., Caron, M. G., Wettstein, J. G. and Hoener, M. C. (2011). TAAR1 activation modulates monoaminergic neurotransmission, preventing hyperdopaminergic and hypoglutamatergic activity. Proc. Natl. Acad. Sci. USA 108(20), 8485–8490.

Maurice, P., Daulat, A.M, Turecek, R., Ivankova-Susankova, K., Zamponi, F., Kamal, M., Clement, N., Guillaume, J.-L., Bettler, B., Gales, C., Delagrange, P. and Jockers, R. (2010). Molecular organization and dynamics of the melatonin MT1 receptor/RGS20/G(i) protein complex reveal asymmetry of receptor dimers for RGS and Gi coupling. EMBO J. 29, 3646-3659.

Vienne, J., Bettler, B., Franken, P. and Tafti, M. (2010). Differential effects of GABA_B receptor subtypes, γ-hydroxybutyric Acid, and Baclofen on EEG activity and sleep regulation. J. Neurosci. 30(42), 14194-14204.

Guetg, N., Abdel Aziz, S., Holbro, N., Turecek R., Rose, T., Seddik, R., Gassmann, M., Moes, S., Jenoe, P, Oertner, T.G., Casanova, E. and Bettler, B. (2010). NMDA receptor-dependent GABA_B receptor internalization via CaMKII phosphorylation of serine 867 in GABA_B1. Proc. Natl. Acad. Sci. USA 107(31), 13924-13929.

Schwenk, J., Metz, M., Zolles, G., Turecek, R., Fritzius, T., Bildl, W., Tarusawa, E., Kulik, A., Unger, A., Ivankova, K., Seddik, R., Tiao, J.Y., Rajalu, M., Trojanova, J., Rohde V., Gassmann, M., Schulte, U., Fakler, B. and Bettler, B. (2010). Native GABA_B receptors are heteromultimers with a family of auxiliary subunits. Nature 465(7295), 231-235. Highlights in Sci. Signal. 3, ec148 (2010); Nat. Struct. Mol. Biol. 17(5), 546 ( 2010).

Catalano, P.N., Di Giorgio, N., Bonaventura, M., Bettler, B., Libertun, C., and Lux-Lantos, V.A. (2010). Lack of functional GABA_B receptors alters GnRH physiology and sexual dimorphic expression of GnRH and GAD-67 in the brain. Am J Physiol Endocrinol Metab. 298(3), E683-96.

Biermann, B., Ivankova-Susankova, K., Bradaia, A., Abdel Aziz, S., Besseyrias, V., Kapfhammer, J.P., Missler, M., Gassmann, M. and Bettler, B. (2010). The sushi domains of GABA_B receptors function as axonal targeting signals. J. Neurosci. 30(4), 1385-1394.

Gangadharan, V., Agarwal, N., Brugger, S., Tegeder, I. Bettler, B., Kuner R., and Kurejova, M. (2009). Conditional gene deletion reveals functional redundancy of GABA_B receptors in peripheral nociceptors in vivo. Mol. Pain 5(68), 1-12.

Bradaia, A., Trube, G., Stalder, H., Norcross, R.D., Ozmen, L., Wettstein, J.G., Pinard A., Buchy D., Gassmann, M., Hoener, M.C. and Bettler, B. (2009). The selective antagonist EPPTB reveals TAAR1-mediated regulatory mechanisms in dopaminergic neurons of the mesolimbic system. Proc. Natl. Acad. Sci. USA 106(47), 20081-20086.

Fernández-Alacid, L., Aguado, C., Ciruela, F., Martín R., Colón J., Cabañero, M. J. Gassmann, M., Watanabe, M., Shigemoto, R., Wickman, K., Bettler, B., Sánchez-Prieto, J. and Luján, R. (2009). Subcellular compartment-specific molecular diversity of pre- and post-synaptic GABA-activated GIRK channels in Purkinje cells. J. Neurochem. 110(4), 1363–1376.

Casanova, E., Guetg, N., Vigot, R., Seddik, R., Julio-Pieper, M., Hyland, N.P., Cryan, J.F., Gassmann, M., and Bettler, B. (2009). A mouse model for visualization of GABA_B receptors. Genesis 47(9), 595-602.

Tchorz, J.S., Kinter J., Müller, M., Tornillo, L., Heim, M.H. and Bettler, B. (2009). Notch2 signalingpromotes biliary epithelial cell fate specification and tubulogenesis during bile duct development in mice. Hepatology 50(3), 871-879.

Guetg, N., Seddik, R., Vigot, R., Turecek, R., Gassmann, M., Vogt, K., Bräuner-Osborne, H., Shigemoto, R., Kretz, O., Frotscher, M., Kulik, A., and Bettler, B. (2009). The GABA_B1a isoform mediates heterosynaptic depression at hippocampal mossy fiber synapses. J. Neurosci. 29(5), 1414-1423.

Wellendorph, P., Johansen, L.D., Jensen, A.A., Casanova, E., Gassmann, M., Deprez, P., Clément-Lacroix, P., Bettler, B., and Bräuner-Osborne H. (2009). No evidence for a bone phenotype in GPRC6A knockout mice under normal physiological conditions. J. Mol. Endocrinol. 42, 215-223.

Matsuki, T., Nomiyama, M., Takahira, H., Hirashima, N., Kunita, S., Takahashi, S., Yagami, K., Kilduff, T.S., Bettler, B., Yanagisawa, M., and Sakurai, T. (2009). Selective loss of GABA_B receptors in orexin-producing neurons results in disrupted sleep/wakefulness architecture. Proc. Natl. Acad. Sci. USA 106(11), 4459-4464. Highlight in Cell 137(3), 389 (2009).

Maison, S.F., Casanova, E., Holstein, G.R., Bettler, B., and Liberman, M.C. (2009). Loss of GABA_B receptors in cochlear neurons: Threshold elevation suggests modulation of outer hair cell function by type-II afferent fibers. J. Assoc. Res. Otolaryngol. 10, 50-63.

Tiao_, J.Y., Bradaia, A., Biermann, B., Kaupmann, K., Metz, M., Haller, C., Rolink, A.G., Pless, E., Barlow, P.N. Gassmann, M. andBettler, B. (2008). The sushi domains of secreted GABA_B1 isoforms selectively impair GABA_B heteroreceptor function. J. Biol. Chem. 283(45), 31005-31011.

Magnaghi, V., Ballabio, M., Camozzi, F., Colleoni, M., Consoli, A., Gassmann, M., Lauria, G., Motta, M., Procacci, P., Trovato, A.E., and Bettler, B. (2008). Altered peripheral myelination in mice lacking GABA_B receptors. Mol. Cell. Neurosci. 37, 599-609.

Lindemann, L., Meyer, C.A., Jeanneau, K., Bradaia, A., Ozmen, L., Bluethmann, H., Bettler, B., Wettstein, J.G. Borroni, E., Moreau, J.-L. and Hoener, M.C. (2008). Trace amine-associated receptor 1 modulates dopaminergic activity J. Pharmacol. Exp. Ther. 324, 948–956.

Bonaventura, M., Catalano, P.N., Chamson-Reig, A., Aranay, E., Hill, D.,Bettler, B., Saravia, F., Libertun, C., and Lux-Lantos, V.A. (2008). GABA_B receptors and glucose homeostasis: Evaluation in GABA_B receptor knockout mice. Am. J. Physiol. Endocrinol. Metab. 294, E157-E167.

Ulrich, D., Besseyrias, V. and Bettler, B. (2007). Functional mapping of GABA_B -receptor subtypes in the thalamus. J. Neurophysiol. 98, 3791–3795.

Cheng, Z., Tu, C., Rodriguez, L., Chen, T.H. Dvorak, M.M., Margeta, M., Gassmann, M., Bettler, B., Shoback, D. and Chang, W. (2007). Type Bgamma-aminobutyric acid receptors modulate the function of the extracellular Ca²⁺-sensing receptor and cell differentiation in murine growth plate chondrocytes. Endocrinology 148(10), 4984–4992.

Chang, W., Tu, C., Cheng, Z., Rodriguez, Chen, T.-H., Gassman, M., Bettler, B., Margeta, M., Jan, L.Y., and Shoback, D. (2007). Complex formation with the type B γ-aminobutyric acid receptor affects the expression and signal transduction of the extracellular calcium-sensing receptor. Studies with HEK-293 cells and neurons. J. Biol. Chem. 282(34), 25030-25040.

Pinheiro, P.S., Perrais, D., Coussen, F., Barhanin, J., Bettler, B., Mann, J.R., Malva, J.O., Heinemann, S.F. and Mulle, C. (2007). GluR7 is an essential subunit of presynaptic kainate autoreceptors at hippocampal mossy fiber synapses. Proc. Natl. Acad. Sci. USA 104(29), 12181-12186.

Ksiazek, I., Burkhardt, C., Lin, S., Seddik, R., Maj, M., Bezakova, G., Jucker, M., Arber, S., Caroni, P., Sanes, J.R., Bettler, B. and Ruegg, M.A. (2007). Synapse loss in cortex of agrin-deficient mice after genetic rescue of perinatal death. J. Neurosci. 27(27),7183–7195.

Jacobson, L.H., Kelly, P.H, Bettler, B., Kaupmann K. and Cryan, J.F. (2007). Specific roles of GABA_B1 receptor isoforms in cognition. Behavioural Brain Research 181, 158-162.

Jacobson, L.H., Bettler, B., Kaupmann, K. and Cryan, J.F. (2007). Behavioural evaluation of mice deficient in GABA_B(1) receptor isoforms in tests of unconditioned anxiety. Psychopharmacology 190, 541-553.

Jacobson, L.H., Bettler, B., Kaupmann, K. and Cryan J.F. (2006). GABA_B(1) receptor subunit isoforms exert a differential influence on baseline but not GABA_B receptor agonist-induced changes in mice.J. Pharmacol. Exp. Ther. 319(3), 1317-1326.

Vigot, R., Barbieri, S., Bräuner-Osborne, H., Turecek, R., Shigemoto, R., Zhang, Y.-P., Luján, R., Jacobson, L.H., Biermann, B., Fritschy, J.-M., Vacher, C.-M., Müller, M., Sansig, G., Guetg, N., Cryan, J.F., Kaupmann, K., Gassmann, M., Oertner, T.G. and Bettler, B. (2006). Differential compartmentalization and distinct functions of GABA_B receptor variants. Neuron 50(4), 589-601. Highlights in Neuron 50(4), 521-524 (2006); Nature 44, 387, (2006); Nature Reviews 7, 506, (2006).

Pérez-Garci, E., Gassmann, M., Bettler, B. and Larkum^. M. E. (2006). The GABA_B1b isoform mediates long-lasting inhibition of dendritic Ca²⁺ spikes in layer 5 somatosensory pyramidal neurons. Neuron 50(4), 603-16.

Shaban, H., Humeau, Y., Herry, C., Cassasus, G., Shigemoto, R., Ciocchi, S., Barbieri, S. van der Putten, H., Kaupmann, K., Bettler, B. and Lüthi A. (2006). Generalization of amygdala LTP and conditioned fear in the absence of presynaptic inhibition. Nature Neurosci. 9(8), 1028-1035.

Jacobson, L.H., Kelly, P.H., Bettler, B., Kaupmann, K. and Cryan J.F. (2006). GABA_B1 receptor isoforms differentially mediate the acquisition and extinction of aversive taste memories. J. Neurosci. 26(34), 8800-8803.

Vacher, C.-M., Gassmann, M., Desrayaud, S., Challet E., Bradaia, A., Hoyer, D., Waldmeier, P., Kaupmann, K., Pévet, P. andBettler, B. (2006). Hyperdopaminergia and altered locomotor activity in GABA_B1-deficient mice. J. Neurochem. 97, 979-991.

Kulik, A., Vida, I., Fukazawa, Y., Guetg, N., Kasugai, Y., Marker, C.L., Rigato, F., Bettler, B., Wickman, K., Frotscher, M. and Shigemoto, R. (2006). Compartment-dependent colocalization of Kir3.2-containing K⁺ channels and GABA_B receptors in hippocampal pyramidal cells. J. Neurosci., 26(16), 4289-4297.

Engle, M.P., Gassmann, M., Sykes K.T., Bettler, B. and Hammond, D.L. (2006). Spinal nerve ligation does not alter the expression or function of GABA_B receptors in spinal cord and dorsal root ganglia of the rat. Neuroscience 138 (4), 1277-1287.

Rey-Roldán, E.B., Bianchi, M.S., Bettler, B., Becu-Villalobos, D., Lux-Lantos, V.A. Libertun, C. (2006). Adenohypophyseal and hypothalamic GABA_B receptor subunits are downregulated by estradiol in adult female rats. Life Sci. 79, 342-350.

Catalano, P.N., Bonaventura, M.M., Silveyra P., Bettler, B., Libertun C. and Lux-Lantos, V.A. (2005). GABA_B1 knockout mice reveal alterations in prolactin levels, gonadotropic axis, and reproductive function. Neuroendocrinology 82, 294-305.

Sauter, K., Grampp, T., Fritschy J.-M., Kaupmann, K., Bettler, B., Mohler, H., Benke, D. (2005). Subtype-selective interaction with the transcription factor CCAAT/enhancer-binding protein (C/EBP) homologous protein (CHOP) regulates cell surface expression of GABA_B receptors. J. Biol. Chem. 280, 33566-33572.

Bianchi, M.S., Lux-Lantos, V.A., Bettler, B. and Libertun, C. (2005). Expression of γ-aminobutyric acid-B receptor subunits in hypothalamus of male and female developing rats. Dev Brain Res. 160, 124-129.

Gassmann, M., Haller, C., Stoll, Y., Aziz S.A., Biermann, B., Mosbacher, J., Kaupmann, K., Bettler, B. (2005). The RXR-Type endoplasmic reticulum-retention/retrieval signal of GABA_B1 requires distant spacing from the membrane to function. Mol. Pharmacol. 68,137-144.

Mombereau, C., Kaupmann, K., Gassmann, M., Bettler, B., Van der Putten, H., Cryan, J.F. (2005). Altered anxiety and depression-related behaviour in mice lacking GABA_B2 receptor subunits. NeuroReport 16(3), 307-310.

Deriu, D., Gassmann, M., Firbank, S., Ristig, D., Lampert, C., Mosbacher, J., Froestl W., Kaupmann, K., Bettler, B., Grütter, M.G. (2005). Determination of the minimal functional ligand-binding domain of the GABA_B(1b) receptor. Biochem. J. 386, 423-431.

Bianchi, M.S., Catalano, P.N., Bonaventura, M.M., Silveyra, P., Bettler, B., Libertun, C. , Lux-Lantos, V.A.R. (2004). Effect of androgens on sexual differentiation of pituitary γ-aminobutyric acid receptor subunit GABA_B expression. Neuroendocrinology 80, 129-142.

Tabata, T., Araishi, K., Hashimoto, K., Hashimotodani, Y., Van der Putten, H., Bettler, B., Kano, M. (2004). Ca²⁺ activity at GABA_B receptors constitutively promotes metabotropic glutamate signaling in the absence of GABA. Proc. Natl. Acad. Sci. USA 101, 16952-16957.

Haller, C., Casanova, E., Müller, M., Vacher, C.-M., Vigot, R., Doll, T., Barbieri, S., Gassmann, M., Bettler, B. (2004). Floxed allele for conditional inactivation of the GABA_B(1) gene. Genesis 40, 125-130.

Rüttimann E., Vacher^, C.-M., Gassmann M., Kaupmann, K., Van der Putten H., Bettler, B. (2004). Altered hippocampal expression of calbindin D-28k and calretinin in GABA_B(1)-deficient mice. Biochem. Pharmacol. 68(8), 1613-1620.

Fritschy, J.-M., Sidler, C., Parpan, F., Gassman, M., Kaupmann, K., Bettler, B., Benke, D. (2004). Independent maturation of the GABA_B receptor subunits GABA_B1 and GABA_B2 during postnatal development in rodent brain. J. Comp. Neurol. 477, 235-252.

Cryan, J.F., Kelly, P.H., Chaperon, F., Gentsch, C., Mombereau, C., Lingenhoehl, K., Froestl W., Bettler, B., Kaupmann, K. , Spooren, W.P.J.M. (2004). Behavioral characterization of the novel GABA_B receptor positive modulator GS39783 (N,N’-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine): anxiolytic-like activity without side-effects associated with baclofen or benzodiazepines. J. Pharmacol. Exp. Ther. 310, 952-963.

Gassmann, M., Shaban, H., Vigot, R., Sansig, G., Haller, C., Barbieri, S., Humeau, Y., Schuler, V., Müller, M., Kinzel, B., Klebs, K., Schmutz, M. , Froestl, W., Heid, J., Kelly, P. H., Gentry, C., Jaton, A.-L., Van der Putten, H., Mombereau, C., Lecourtier, L., Mosbacher, J., Cryan, J. F., Fritschy, J.-M., Lüthi, A., Kaupmann, K., Bettler, B. (2004). Redistribution of GABA_B(1) protein and atypical GABA_B responses in GABA_B(2)-deficient mice. J. Neurosci. 24, 6086-6097.

Kaupmann, K., Cryan, J.F., Wellendorph, P., Mombereau, C., Sansig, G., Klebs, K., Schmutz, M., Froestl, W., Van der Putten, H., Mosbacher, J., Bräuner-Osborne, H., Waldmeier, P., Bettler, B. (2003). Specific γ-hydroxybutyrate-binding sites but loss of pharmacological effects of γ-hydroxybutyrate in GABA_B(1)-deficient mice. Eur. J. Neurosci. 18, 2722-2730.

Furtinger, S.,Bettler, B., Sperk, G. (2003). Altered expression of GABA_B receptors in the hippocampus after kainic acid-induced seizures in rats. Mol. Brain. Res. 113, 107-115.

Saghatelyan A.K., Snapyan M., Gorissen S., Meigel I., Mosbacher J., Kaupmann K., Bettler, B., Kornilov A.V., Nifantiev N.E., Sakanyan V., Schachner M., Dityatev A. (2003). Recognition molecule associated carbohydrate inhibits postsynaptic GABA_B receptors: a mechanism for homeostatic regulation of GABA release in perisomatic synapses. Mol. Cell. Neurosci. 24, 271-282.

Froestl, W., Bettler, B., Bittiger, H., Heid, J., Kaupmann, K., Mickel, S.J., Strub, D. (2003). Ligands for expression cloning and isolation of GABA_B receptors. Farmaco 58, 173-183.

Havlickova, M., Prezeau, L., Duthey, B., Bettler, B., Pin, J.-P., Blahos, J. (2002). The intracellular loops of the GB2 subunit are crucial for G-protein coupling of the heteromeric gamma-aminobutyrate B receptor. Mol. Pharmacol. 62, 343-350.

Jensen, A.A., Mosbacher, J., Elg, S., Lingenhoehl, K., Lohmann, T., Johansen, T.N., Abrahamsen, B., Mattson, J.P., Lehmann, A., Bettler, B., Bräuner-Osborne, H. (2002). The anticonvulsant gabapentin (Neurontin) does not act through GABA_B receptors. Mol. Pharmacol. 61, 1377-1384.

Kulik, A., Nakadate, K., Nyiri, G., Notomi, T., Malitschek, B., Bettler, B., Shigemoto, R. (2002). Distinct localization of GABA_B receptors relative to synaptic sites in the rat cerebellum and ventrobasal thalamus.Europ. J. Neurosci. 15, 291-307.

Duthey, B., Caudron, S., Perroy, J., Bettler, B., Fagni, L., Pin, J.-P., Prézeau, L. (2002). A single subunit (GB2) is required for G-protein activation by the heterodimeric GABA_B receptor. J. Biol. Chem. 277, 3236-3241.

Urwyler, S., Mosbacher J., Lingenhoehl K., Heid, J. Hofstetter, K. Froestl, W., Bettler, B., Kaupmann K. (2001). Positive allosteric modulation of native and recombinant GABA_B receptors by 2,6-Di-tert.-butyl-4-(3-hydroxy-2,2-dimethyl-propyl)-phenol (CGP7930) and its aldehyde analog CGP13501. Mol. Pharmacol. 60, 963-971. (With accompanying “Perspectives” Article).

Schuler, V., Lüscher C., Blanchet, C, Klix, N., Sansig, G., Klebs, K., Schmutz, M,. Heid, J., Gentry, C., Urban, L., Fox, A., Spooren, W., Jaton, A.-L., Vigouret, J.-M., Pozza, M., Kelly, P.H., Mosbacher, J., Fröstl, W., Käslin, E., Korn, R., Bischoff, S., Kaupmann, K., Van der Putten, H., Bettler, B. (2001). Epilepsy, hyperalgesia, impaired memory, and loss of pre-and postsynaptic GABA_B responses in mice lacking GABA_B(1). Neuron 31, 47-58.

Froestl, W., Bettler, B., Bittiger, H., Heid, J., Kaupmann, K., Mickel, S.J., Strub, D. (2001). Ligands for expression cloning and isolation of GABA_B receptors. Farmaco 56 (1-2), 101-105.

Galvez, T., Duthey, B., Kniazeff, J., Blahos, J., Rovelli, G., Bettler, B., Prézeau, L., Pin, J.-P. (2001). Allosteric interactions between GB1 and GB2 subunits are required for optimal GABA_B receptor function. EMBO J. 20 (9), 2152-2159.

Gonchar, Y., Pang, L., Malitschek, B., Bettler, B., Burkhalter, A. (2001). Subcellular localization of GABA_B receptor subunits in rat visual cortex. J. Comp. Neurol. 431 (2), 182-197.

Pagano, A., Rovelli, G., Mosbacher, J., Lohmann, T., Duthey, B,, Stauffer, D., Ristig, D., Schuler, V., Meigel, I., Lampert, C., Stein, T., Prézeau, L., Blahos, J., Pin, J.-P., Froestl, W., Kuhn, R., Heid, J. Kaupmann, K., Bettler, B. (2001). C-terminal interaction is essential for surface trafficking but not for heteromeric assembly of GABA_B receptors. J. Neurosci. 21 (4), 1189-1202.

Bianchi. M., Rey-Roldán, E., Bettler, B., Ristig, D., Malitschek, B, Libertun C., Lux-Lantos, V. (2001). Ontogenic expression of anterior pituitary GABA_B receptor subunits. Neuropharmacology 40, 185-192.

Galvez, T., Pezeau, L., Milioti, G., Franek, M., Joly, C., Froestl, W., Bettler, B., Bertrand, H.-O., Blahos, J., Pin, J.-P. (2000). Mapping the Agonist-Binding Site of GABA_B type 1 Subunit Sheds Light on the Activation Process of GABA_B Receptors. J. Biol. Chem. 275, 41166-41174.

Mulle, C., Sailer, A., Swanson, G.T., Brana, C., O'Gorman, S., Bettler, B., Heinemann, S.F. (2000). Subunit composition of kainate receptors in hippocampal interneurons. Neuron 28, 475-484.

Lorente, P., Lacampagne, A., Pouzeratte Y., Richards, S., Malitschek, B., Kuhn, R., Bettler, B., Vassort, G. (2000). γ-aminobutyric acid type B receptors are expressed and functional in mammalian cardiomyocytes. Proc. Natl. Acad Sci. USA 97, 8664-8669.

Towers, S., Princivalle, A., Billinton, A., Edmunds, M., Bettler, B., Urban, L., Castro-Lopes, J., Bowery, N.G. (2000). GABA_B receptor protein and mRNA distribution in rat spinal cord and dorsal root ganglia.Europ. J. Neurosci. 12, 3201-3210.

Galvez, T., Urwyler, S., Prézeau L., Mosbacher, J., Joly, C., Malitschek, B., Heid, J., Brabet, I., Froestl, W., Bettler, B., Kaupmann, K., Pin, J.-P. (2000). Ca²⁺ requirement for high-affinity γ-aminobutyric acid (GABA) binding at GABA_B receptors: Involvement of serine 269 of the GABA_BR1 subunit. Mol. Pharmacol. 57, 419-426.

Keir, M.J., Barakat, M.J., Dev, K.K., Bittiger, H., Bettler, B., Henley, H. (1999). Characterization and partial purification of the GABA_B receptor from the rat cerebellum using the novel antagonist [³H]CGP62349. Mol. Brain Res. 71 (2), 279-289.

Franek, M., Pagano, A., Kaupmann, K., Bettler, B., Pin, J.-P., Blahos, J. (1999). The heteromeric GABA_B receptor recognizes G-protein α subunit C-termini. Neuropharmacology 38, 1657-1666.

Froestl, W., Bettler, B., Bittiger, H., Heid, J. Kaupmann, K. Mickel, S. J, Strub, D. (1999). Ligands for the isolation of GABA_B receptors. Neuropharmacology 38, 1641-1646.

Lingenhoehl, K., Brom, R., Heid, J., Beck, P., Froestl, W., Kaupmann, K., Bettler, B., Mosbacher, J. (1999). γ-Hydroxybutyrate is a weak agonist at recombinant GABA_B receptors. Neuropharmacology 38, 1667-1673.

Benke, D., Honer, M., Michel, B., Bettler, B. and Möhler, H. (1999). γ-Aminobutyric acid type B receptor splice variant proteins GBR1a and GBR1b are both associated with GBR2 in situ and display differential regional and subcellular distribution. J. Biol. Chem. 274, 27323-27330.

Pfaff, T., Malitschek, B., Kaupmann, K., Prézeau, L., Pin, J.-P., Bettler, B., Karschin, A. (1999). Alternative splicing generates a novel isoform of the rat metabotropic GABA_BR1 receptor. Europ. J. Neurosci. 11, 2874-2882.

Bischoff, S, Leonhard, S., Reymann, N., Schuler, V., Shigemoto, R., Kaupmann, K., Bettler, B. (1999). Spatial distribution of GABA_BR1 receptor mRNA and binding sites in the rat brain. J. Comp. Neurol. 412, 1-16.

Malitschek, B., Schweizer, C., Keir, M., Heid, J., Froestl, W., Mosbacher, J., Kuhn, R., Henley, J., Joly, C., Pin, J.-P., Kaupmann, K., Bettler, B. (1999). The N-terminal domain of GABA_B receptors is sufficient to specifiy agonist and antagonist binding. Mol. Pharmacol. 56 (2), 448-454.

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