Development and Evolution

Dr. Javier Lopez-Rios

Department of Biomedicine
University of Basel
Mattenstrasse 28 4058 Basel
T:+41 (0)61 207 50 34

Research Focus

A fascinating challenge in biology is to unravel the mechanisms underlying the evolutionary diversification of animal form. We combine functional genomics in mouse, cow and pig embryos with the strengths of mouse genetics to gain mechanistic knowledge into gene regulatory networks operating in development and how they have been rewired for morphological evolution of the vertebrate limb skeleton. Most importantly, by studying how form is genetically encoded, our goal is to gain fundamental insight into the etiology of human congenital malformations.