Cell and Gene Therapy


1)    Ozawa C.R.*, Banfi A.*, Glazer N., Thurston G., Springer M.L., Kraft P.E., McDonald D.M. and Blau H.M. (2004). Microenvironmental VEGF concentration, not total dose, determines a threshold between normal and aberrant angiogenesis. J. Clin. Invest. 113, 516-527.

2)    Banfi A., von Degenfeld G. and Blau H.M. (2005). Critical role of microenvironmental factors in angiogenesis. Curr. Atheroscler. Rep. 7, 227-234.

3)    von Degenfeld G., Banfi A., Springer M.L., Jacobi J., Ozawa C.R., Merchant M.J., Cooke J.P. and Blau H.M. (2006). Microenvironmental concentration of VEGF is critical to stable and functional vessel growth in ischemia. FASEB J. 20, 2657-2659, DOI: 10.1096/fj.06-6568fje.

4)    Misteli H., Wolff T., Füglistaler P., Gianni-Barrera R., Gürke L., Heberer M. and Banfi A. (2010). High-throughput FACS purification of transduced progenitors expressing defined VEGF levels induces controlled angiogenesis in vivo. Stem Cells 28, 611-619.

5)    Kupatt C., Hinkel R., Pfosser A., El-Aouni C., Wuchrer A., Fritz A., Globisch F., Thormann M., Horstkotte J., Lebherz C., Thein E., Banfi A., Boekstegers P. (2010). rAAV-cotransfection of VEGF-A and PDGF-B resolves chronic ischemic malperfusion: Role of vessel maturation. J. Am. Coll. Cardiol. 56, 414-422.

6)    Scherberich A., Müller A.M., Schäfer D.J., Banfi A. and Martin I. (2010) Adipose tissue-derived progenitors for engineering osteogenic and vasculogenic grafts. J. Cell. Physiol. 225, 348-353.

7)    Wolff T., Mujagic E., Gianni-Barrera R., Füglistaler P., Helmrich U., Misteli H., Gürke L., Heberer M. and Banfi A. (2011). FACS-purified myoblasts producing controlled VEGF levels induce safe and stable angiogenesis in chronic hind limb ischemia. J. Cell. Mol. Med. DOI: 10.1111/j.1582-4934.2011.01308.x

8)    Banfi A., von Degenfeld G., Gianni-Barrera R., Merchant M.J., McDonald D.M. and Blau H.M. Coordinated expression of VEGF and PDGF-BB ensures robust therapeutic angiogenesis and recovery form ischemia. Submitted

9)     Di Maggio N., Mehrkens A., Schaeren S., Heberer M., Banfi A.* and Martin I*. FGF-2 maintains a niche-dependent population of self-renewing highly potent non-adherent mesenchymal progenitors through FGFR2c. Submitted

10)     Melly L.F., Marsano A., Helmrich U., Heberer M., Eckstein F.S., Carrel T.P., Giraud-Flück M.N., Tevaearai H.T. and Banfi A. Controlled angiogenesis in the heart by cell-based expression of specific VEGF levels. Submitted