Bioinformatics Core Facility
The Bioinformatics Core Facility provides a centralized resource of expertise in computational biology and statistics. It offers solutions for analysis, visualization, management and interpretation of high-throughput genomic data (microarrays and next generation sequencing). Beside the standardized approaches, the platform can also provide customized solutions tailored towards the needs of individual research projects.
The facility also provides regular bioinformatics training. Together with bioinformaticians from the Friedrich Miescher Institute for Biomedical Research we organize "R Introductory Course". This five-day practical course provides beginners with basic knowledge of the R software environment and with training on how to explore and visualize the data and perform wide range of statistical tests. We also offer a lecture once per semester entitled “Introduction to Bioconductor”. Here we cover several topics of genomics data analysis including differential expression using microarray or RNA-seq, ChIP-seq analysis and an overview of the Bioconductor infrastructure.
The platform's mission is to build and maintain an infrastructure that enables application of strong bioinformatics analysis to enhance and empower the biomedical research at the DBM. However, the rapid technological advances and the growing number of bioinformatics approaches and tools make it difficult to keep track of with limited resources at the facility. Therefore the Bioinformatics Core Facility closely interacts with other bioinformatics units in the Basel area, namely with the group of Dr. Michael Stadler (Friedrich Miescher Institute for Biomedical Research) and the group of Prof. Torsten Schwede (Center for scientific computing at the University of Basel - sciCORE) in order to implement the latest bioinformatics approaches.
The facility is part of Swiss Institute of Bioinformatics since January 2017.