Publications

Navarini, A. A., Hruz, P., Berger, C. T., Hou, T. Z., Schwab, C., Gabrysch, A., Higgins, R., Frede, N., Padberg Sgier, B.-C., Kämpe, O., Burgener, A.-V., Marquardsen, F., Baldin, F., Bigler, M., Kistner, A., Jauch, A., Bignucolo, O., Meyer, B., Meienberg, F., Mehling, M., Jeker, L. T., Heijnen, I., Daikeler, T. D., Gebbers, J.-O., Grimbacher, B., Sansom, D. M., Jeker, R., Hess, C. and Recher, M. (2017) ‘Vedolizumab as a successful treatment of CTLA-4-associated autoimmune enterocolitis’, The Journal of allergy and clinical immunology, 139(3), pp. 1043-1046e5. doi: 10.1016/j.jaci.2016.08.042.   
Pisarsky, L., Bill, R., Fagiani, E., Dimeloe, S., Goosen, R. W., Hagmann, J., Hess, C. and Christofori, G. (2016) ‘Targeting Metabolic Symbiosis to Overcome Resistance to Anti-angiogenic Therapy’, Cell Reports, 15(6), pp. 1161-1174. doi: 10.1016/j.celrep.2016.04.028.   edoc | Open Access
Recher, M., Berger, C. T., Daikeler, T., Hess, C. and Heijnen, I. A. F. M. (2016) ‘A “Too Negative” ANA Test Predicts Antibody Deficiency’, Journal of Clinical Immunology, 36(4), pp. 374-376. doi: 10.1007/s10875-016-0262-9.   edoc
Berger, C. T. and Hess, C. (2016) ‘Neglected for too long? - CD8+ Tregs release NOX2-loaded vesicles to inhibit CD4+ T cells’, The Journal for Clinical Investigation, 126(5), pp. 1646-1648. doi: 10.1172/JCI87429.   edoc
Balmer, M. L., Ma, E. H., Bantug, G. R., Grahlert, J., Pfister, S., Glatter, T., Jauch, A., Dimeloe, S., Slack, E., Dehio, P., Krzyzaniak, M. A., King, C. G., Burgener, A. V., Fischer, M., Develioglu, L., Belle, R., Recher, M., Bonilla, W. V., Macpherson, A. J., Hapfelmeier, S., Jones, R. G. and Hess, C. (2016) ‘Memory CD8(+) T Cells Require Increased Concentrations of Acetate Induced by Stress for Optimal Function’, Immunity, 44(6), pp. 1312-1324. doi: 10.1016/j.immuni.2016.03.016.   
Dimeloe, S., Mehling, M., Frick, C., Loeliger, J., Bantug, G. R., Sauder, U., Fischer, M., Belle, R., Develioglu, L., Tay, S., Langenkamp, A. and Hess, C. (2016) ‘The Immune-Metabolic Basis of Effector Memory CD4+ T Cell Function under Hypoxic Conditions’, J Immunol, 196(1), pp. 106-114. doi: 10.4049/jimmunol.1501766.   
Berger, C. T., Baldi, T., Aschwanden, M., Scherer, K., Recher, M., Hess, C. and Daikeler, T. (2015) ‘Diagnosis at your fingertips: splinters and microemboli – is it SLE?’, Lupus. Sage Publications, 24(3), pp. 341-342. doi: 10.1177/0961203314558862.   edoc
Hönger, G., Krähenbühl, N., Dimeloe, S., Stern, M., Schaub, S. and Hess, C. (2015) ‘Inter-individual differences in HLA expression can impact the CDC crossmatch’, Tissue Antigens, 85(4), pp. 260-266. doi: 10.1111/tan.12537.   edoc
Kolev, M., Dimeloe, S., Le Friec, G., Navarini, A., Arbore, G., Povoleri, G. A., Fischer, M., Belle, R., Loeliger, J., Develioglu, L., Bantug, G. R., Watson, J., Couzi, L., Afzali, B., Lavender, P., Hess, C. and Kemper, C. (2015) ‘Complement Regulates Nutrient Influx and Metabolic Reprogramming during Th1 Cell Responses’, Immunity. Cell Press; Elsevier, 42(6), pp. 1033-1047. doi: 10.1016/j.immuni.2015.05.024.   edoc | Open Access
Marschall, K., Hoernes, M., Bitzenhofer-Gruber, M., Jandus, P., Duppenthaler, A., Wuillemin, W. A., Rischewski, J., Boyman, O., Heininger, U., Hauser, T., Steiner, U., Posfay-Barbe, K., Seebach, J., Recher, M., Hess, C., Helbling, A., Reichenbach, J. and Swiss, P. I. D. R. W. G. (2015) ‘The Swiss National Registry for Primary Immunodeficiencies: report on the first 6 years’ activity from 2008 to 2014’, Clinical & Experimental Immunology. Wiley Blackwell - STM, 182(1), pp. 45-50. doi: 10.1111/cei.12661.   edoc | Open Access
Mehling, M., Burgener, A. V., Brinkmann, V., Bantug, G. R., Dimeloe, S., Hoenger, G., Kappos, L. and Hess, C. (2015) ‘Tissue Distribution Dynamics of Human NK Cells Inferred from Peripheral Blood Depletion Kinetics after Sphingosine-1-Phosphate Receptor Blockade’, Scandinavian Journal of Immunology. Wiley-Blackwell - STM, 82(5), pp. 460-466. doi: 10.1111/sji.12347.   edoc
Nowakowska, J., Stuehler, C., Egli, A., Battegay, M., Rauser, G., Bantug, G. R., Brander, C., Hess, C. and Khanna, N. (2015) ‘T cells specific for different latent and lytic viral proteins efficiently control Epstein-Barr virus-transformed B cells’, Cytotherapy. Elsevier, 17(9), pp. 1280-1291. doi: 10.1016/j.jcyt.2015.06.003.   edoc
Berger, C., Greiff, V., John, S., Koenig, K., Bigler, M., Recher, M., Hess, C. and Daikeler, T. (2015) ‘Risk factors for pneumocystis pneumonia in giant cell arteritis: a single-centre cohort study’, Clinical and Experimental Rheumatology. Clinical and Experimental Rheumatology, 33(2, Suppl 89), pp. 122-125.   edoc
Berger, C. T., Greiff, V., Mehling, M., Fritz, S., Meier, M. A., Hoenger, G., Conen, A., Recher, M., Battegay, M., Reddy, S. T. and Hess, C. (2015) ‘Influenza vaccine response profiles are affected by vaccine preparation and preexisting immunity, but not HIV infection’, Human Vaccines & Immunotherapeutics. Taylor & Francis, 11(2), pp. 391-396. doi: 10.1080/21645515.2015.1008930.   edoc | Open Access
Haering, M., Holbro, A., Todorova, M. G., Aschwanden, M., Kesten, F., Berger, C. T., Tyndall, A., Benz, D., Hess, C. and Daikeler, T. (2014) ‘Incidence and prognostic implications of diplopia in patients with giant cell arteritis’, J Rheumatol, 41(7), pp. 1562-1564. doi: 10.3899/jrheum.130983.   
Dimeloe, S., Frick, C., Fischer, M., Gubser, P. M., Razik, L., Bantug, G. R., Ravon, M., Langenkamp, A. and Hess, C. (2014) ‘Human regulatory T cells lack the cyclophosphamide-extruding transporter ABCB1 and are more susceptible to cyclophosphamide-induced apoptosis’, Eur J Immunol, 44(12), pp. 3614-3620. doi: 10.1002/eji.201444879.   
Recher, M., Karjalainen-Lindsberg, M. L., Lindlof, M., Soderlund-Venermo, M., Lanzi, G., Vaisanen, E., Kumar, A., Sadeghi, M., Berger, C. T., Alitalo, T., Anttila, P., Kolehmainen, M., Franssila, R., Chen, T., Siitonen, S., Delmonte, O. M., Walter, J. E., Pessach, I., Hess, C., Simpson, M. A., Navarini, A. A., Giliani, S., Hedman, K., Seppanen, M. and Notarangelo, L. D. (2014) ‘Genetic variation in schlafen genes in a patient with a recapitulation of the murine Elektra phenotype’, J Allergy Clin Immunol, 133(5), pp. 1462-5,1465e1. doi: 10.1016/j.jaci.2013.10.052.   
Mehling, M., Eichin, D., Hafner, P., Honger, G., Kappos, L. and Hess, C. (2014) ‘Avidity of vaccine-induced influenza IgG fails to increase in fingolimod-treated patients with MS’, Neurol Neuroimmunol Neuroinflamm, 1(3), p. e28. doi: 10.1212/NXI.0000000000000028.   
Gonzalez, A., Schmitter, K., Hirsch, H. H., Garzoni, C., van Delden, C., Boggian, K., Mueller, N. J., Berger, C., Villard, J., Manuel, O., Meylan, P., Stern, M., Hess, C. and Swiss Transplant Cohort, S. (2014) ‘KIR-associated protection from CMV replication requires pre-existing immunity: a prospective study in solid organ transplant recipients’, Genes Immun, 15(7), pp. 495-499. doi: 10.1038/gene.2014.39.   
Donath, M. Y., Hess, C. and Palmer, E. (2014) ‘What is the role of autoimmunity in type 1 diabetes? A clinical perspective’, Diabetologia, 57(4), pp. 653-655. doi: 10.1007/s00125-013-3153-0.   
Mehling, M., Fritz, S., Hafner, P., Eichin, D., Yonekawa, T., Klimkait, T., Lindberg, R. L., Kappos, L. and Hess, C. (2013) ‘Preserved Antigen-Specific Immune Response in Patients with Multiple Sclerosis Responding to IFNbeta-Therapy’, PLoS ONE. Public Library of Science, 8(11), p. e78532. doi: 10.1371/journal.pone.0078532.   edoc
Gubser, P. M., Bantug, G. R., Razik, L., Fischer, M., Dimeloe, S., Hoenger, G., Durovic, B., Jauch, A. and Hess, C. (2013) ‘Rapid effector function of memory CD8+ T cells requires an immediate-early glycolytic switch’, Nature immunology. Nature America, 14(10), pp. 1064-1072. doi: 10.1038/ni.2687.   edoc
Gasser, O., Brander, C., Wolbers, M., Brown, N. V., Rauch, A., Gunthard, H. F., Battegay, M. and Hess, C. (2013) ‘Expansion of interferon-gamma-secreting HIV-specific T cells during successful antiretroviral therapy’, HIV medicine. Blackwell, 14(4), pp. 241-246. doi: 10.1111/j.1468-1293.2012.01040.x.   edoc
Mehling, M., Brinkmann, V., Burgener, A. V., Gubser, P., Luster, A. D., Kappos, L. and Hess, C. (2013) ‘Homing frequency of human T cells inferred from peripheral blood depletion kinetics after sphingosine-1-phosphate receptor blockade’, Journal of allergy and clinical immunology. Mosby, 131(5), pp. 1440-3.e7. doi: 10.1016/j.jaci.2012.12.1520.   edoc
Recher, M., Fried, A. J., Massaad, M. J., Kim, H. Y., Rizzini, M., Frugoni, F., Walter, J. E., Mathew, D., Eibel, H., Hess, C., Giliani, S., Umetsu, D. T., Notarangelo, L. D. and Geha, R. S. (2013) ‘Intronic SH2D1A mutation with impaired SAP expression and agammaglobulinemia’, Clinical immunology. Elsevier, 146(2), pp. 84-89. doi: 10.1016/j.clim.2012.11.007.   edoc
Durovic, B., Gasser, O., Gubser, P., Sigle, J., Hirsch, H. H., Stern, M., Buser, A. and Hess, C. (2013) ‘Epstein-Barr virus negativity among individuals older than 60 years is associated with HLA-C and HLA-Bw4 variants and tonsillectomy’, Journal of virology. American Society for Microbiology, 87(11), pp. 6526-6529. doi: 10.1128/jvi.00169-13.   edoc
Henn, M. R., Boutwell, C. L., Charlebois, P., Lennon, N. J., Power, K. A., Macalalad, A. R., Berlin, A. M., Malboeuf, C. M., Ryan, E. M., Gnerre, S., Zody, M. C., Erlich, R. L., Green, L. M., Berical, A., Wang, Y., Casali, M., Streeck, H., Bloom, A. K., Dudek, T., Tully, D., Newman, R., Axten, K. L., Gladden, A. D., Battis, L., Kemper, M., Zeng, Q., Shea, T. P., Gujja, S., Zedlack, C., Gasser, O., Brander, C., Hess, C., Gunthard, H. F., Brumme, Z. L., Brumme, C. J., Bazner, S., Rychert, J., Tinsley, J. P., Mayer, K. H., Rosenberg, E., Pereyra, F., Levin, J. Z., Young, S. K., Jessen, H., Altfeld, M., Birren, B. W., Walker, B. D. and Allen, T. M. (2012) ‘Whole genome deep sequencing of HIV-1 reveals the impact of early minor variants upon immune recognition during acute infection’, PLoS Pathogens. Public Library of Science, 8(3), p. e1002529. doi: 10.1371/journal.ppat.1002529.   edoc
Holbro, A., Jauch, A., Lardinois, D., Tzankov, A., Dirnhofer, S. and Hess, C. (2012) ‘High prevalence of infections and autoimmunity in patients with thymoma’, Human immunology. Elsevier, 73(3), pp. 287-290. doi: 10.1016/j.humimm.2011.12.022.   edoc
Stern, M., Czaja, K., Rauch, A., Rickenbach, M., Gunthard, H. F., Battegay, M., Fellay, J., Hirschel, B., Hess, C. and Swiss, H. I. V. C. S. G. (2012) ‘HLA-Bw4 identifies a population of HIV-infected patients with an increased capacity to control viral replication after structured treatment interruption’, HIV medicine. Blackwell, 13(10), pp. 589-595. doi: 10.1111/j.1468-1293.2012.01019.x.   edoc
Durovic, B., Zenhaeusern, G., Hoenger, G., Gasser, O., Schaub, S. and Hess, C. (2011) ‘Allo-induced acute-phase response : IL-6 identifies a subset of individuals at risk for graft injury’, Scandinavian journal of immunology. Blackwell, 73(2), pp. 156-158. doi: 10.1111/j.1365-3083.2010.02489.x.   edoc
Daikeler, T., Tzankov, A., Hoenger, G., Gasser, O., Tyndall, A., Gratwohl, A. and Hess, C. (2011) ‘Minimal T-cell requirements for triggering haemophagocytosis associated with Epstein-Barr virus-driven B-cell proliferation : a clinical case study’, Annals of the rheumatic diseases. British Medical Association, 70(7), pp. 1338-1339. doi: 10.1136/ard.2010.139246.   edoc
Mehling, M., Hilbert, P., Fritz, S., Durovic, B., Eichin, D., Gasser, O., Kuhle, J., Klimkait, T., Lindberg, R. L. P., Kappos, L. and Hess, C. (2011) ‘Antigen-specific adaptive immune responses in fingolimod-treated multiple sclerosis patients’, Annals of neurology. Wiley-Liss, 69(2), pp. 408-413. doi: 10.1002/ana.22352.   edoc
Daikeler, T., Hoenger, G., Oehri, I., Tyndall, A., Gratwohl, A., Brander, C., Klimkait, T., Gasser, O. and Hess, C. (2011) ‘Dominant Epstein-Barr virus-specific T-cell responses are maintained during moderate and intense immunosuppressive treatment’, Annals of the rheumatic diseases. British Medical Association, 70(2), pp. 395-396. doi: 10.1136/ard.2010.129734.   edoc
Stern, M., Hadaya, K., Honger, G., Martin, P. Y., Steiger, J., Hess, C. and Villard, J. (2011) ‘Telomeric rather than centromeric activating KIR genes protect from cytomegalovirus infection after kidney transplantation’, American journal of transplantation. Munksgaard, 11(6), pp. 1302-1307. doi: 10.1111/j.1600-6143.2011.03516.x.   edoc
Kesten, F., Aschwanden, M., Gubser, P., Glatz, K., Daikeler, T. and Hess, C. (2011) ‘Giant cell arteritis : a changing entity’, Swiss Medical Weekly. EMH, Vol. 141 , w13272. doi: 10.4414/smw.2011.13272.   edoc
Gasser, O., Zenhaeusern, G., Hönger, G., Brander, C. and Hess, C. (2011) ‘Immunosuppressive drugs asymmetrically impact circulating T cell counts and function’, Scandinavian journal of immunology. Blackwell, 73(1), pp. 76-77. doi: 10.1111/j.1365-3083.2010.02472.x.   edoc
Aschwanden, M., Kesten, F., Stern, M., Thalhammer, C., Walker, U. A., Tyndall, A., Jaeger, K. A., Hess, C. and Daikeler, T. (2010) ‘Vascular involvement in patients with giant cell arteritis determined by duplex sonography of 2x11 arterial regions’, Annals of the rheumatic diseases. British Medical Association, 69(7), pp. 1356-1359. doi: 10.1136/ard.2009.122135.   edoc
Fritz, S., Mossdorf, E., Durovic, B., Zenhaeusern, G., Conen, A., Steffen, I., Battegay, M., Nüesch, R. and Hess, C. (2010) ‘Virosomal influenza-vaccine induced immunity in HIV-infected individuals with high versus low CD4+ T-cell counts : clues towards a rational vaccination strategy’, AIDS. Current Science, 24(14), pp. 2287-2289. doi: 10.1097/QAD.0b013e32833c6f92.   edoc
Mehling, M., Lindberg, R., Raulf, F., Kuhle, J., Hess, C., Kappos, L. and Brinkmann, V. (2010) ‘Th17 central memory T cells are reduced by FTY720 in patients with multiple sclerosis’, Neurology. Lancet Publications, 75(5), pp. 403-410. doi: 10.1212/WNL.0b013e3181ebdd64.   edoc
Stern, M., Opelz, G., Döhler, B. and Hess, C. (2010) ‘Natural killer-cell receptor polymorphisms and posttransplantation non-Hodgkin lymphoma’, Blood. American Society of Hematology, 115(19), pp. 3960-3965. doi: 10.1182/blood-2009-10-250134.   edoc
Cantoni, N., Meyer, P., Katan, M., Kappos, L., Hess, C. and Daikeler, T. (2010) ‘A confusing patient’s history : small or large vessel vasculitis?’, Rheumatology international. Springer International, 30(12), pp. 1681-1683. doi: 10.1007/s00296-009-1144-8.   edoc
Zenhaeusern, G., Hönger, G., Gasser, O., Steiger, J., Schaub, S. and Hess, C. (2009) ‘CD56(bright) natural killer cells expand and contract irrespective of CD25 antibody treatment in kidney allograft recipients’, Scandinavian journal of immunology. Blackwell, 69(5), pp. 465-467. doi: 10.1111/j.1365-3083.2009.02236.x.   edoc
Berger, C. T., Wolbers, M., Meyer, P., Daikeler, T. and Hess, C. (2009) ‘High incidence of severe ischaemic complications in patients with giant cell arteritis irrespective of platelet count and size, and platelet inhibition’, Rheumatology : official journal of the British Society for Rheumatology. Univ. Press, 48(3), pp. 258-261.   edoc
Mayr, M., Kim, M. J., Wanner, D., Helmut, H., Schroeder, J. and Mihatsch, M. J. (2009) ‘Argyria and decreased kidney function: are silver compounds toxic to the kidney?’, American journal of kidney diseases : the official journal of the National Kidney Foundation, 53(5), pp. 890-894.   edoc
Zenhaeusern, G., Gasser, O., Hönger, G., Durovic, B., Stern, M. and Hess, C. (2009) ‘Regulatory allospecific NK cell function is differentially associated with HLA C allotypes’, American journal of transplantation : official journal of the American Society of Transplant Surgeons (ASTS) and the American Society of Transplantation (AST). Munksgaard, 9(11), pp. 2624-2630.   edoc
Gasser, O., Bihl, F., Sanghavi, S., Rinaldo, C., Rowe, D., Hess, C., Stablein, D., Roland, M., Stock, P. and Brander, C. (2009) ‘Treatment-dependent loss of polyfunctional CD8+ T-cell responses in HIV-infected kidney transplant recipients is associated with herpesvirus reactivation’, American journal of transplantation : official journal of the American Society of Transplant Surgeons (ASTS) and the American Society of Transplantation (AST). Munksgaard, 9(4), pp. 794-803.   edoc
Holbro, A., Schuetz, P., Berger, C., Hess, C. and Daikeler, T. (2009) ‘Lymphocyte counts in patients with ANCA-associated vasculitis’, Rheumatology international : clinical and experimental investigations. Springer International, 29(7), pp. 807-810.   edoc
Schaub, S., Nickerson, P., Rush, D., Mayr, M., Hess, C., Golian, M., Stefura, W. and Hayglass, K. (2009) ‘Urinary CXCL9 and CXCL10 levels correlate with the extent of subclinical tubulitis’, American journal of transplantation : official journal of the American Society of Transplant Surgeons (ASTS) and the American Society of Transplantation (AST). Munksgaard, 9(6), pp. 1347-1353.   edoc
Daikeler, T., Regenass, S., Tyndall, A., Gencay, M. M., Roth, M., Christ-Crain, M., Müller, B. and Hess, C. (2008) ‘Increased serum levels of soluble triggering receptor expressed on myeloid cells-1 in antineutrophil cytoplasmic antibody-associated vasculitis’, Annals of the rheumatic diseases. British Medical Association, 67(5), pp. 723-724. doi: 10.1136/ard.2007.076547.   edoc
Gasser, O., Berger, C., Zenhaeusern, G., Elsässer, H., Oehri, I., Schaub, S. and Hess, C. (2008) ‘Testing the “cytokine-ome” theory : a longitudinal pilot study in renal transplant recipients’, Transplantation. Lippincott Williams & Wilkins, 85(3), pp. 491-492. doi: 10.1097/TP.0b013e318160eeb6.   edoc
Eken, C., Gasser, O., Zenhaeusern, G., Oehri, I., Hess, C. and Schifferli, J. A. (2008) ‘Polymorphonuclear neutrophil-derived ectosomes interfere with the maturation of monocyte-derived dendritic cells’, Journal of immunology. American Assoc. of Immunologists, 180(2), pp. 817-824.   edoc
Stern, M., Elsässer, H., Hönger, G., Steiger, J., Schaub, S. and Hess, C. (2008) ‘The number of activating KIR genes inversely correlates with the rate of CMV infection/reactivation in kidney transplant recipients’, American journal of transplantation. Munksgaard, 8(6), pp. 1312-1317.   edoc