Publications

Liu, L., Sun, Q., Bao, R., Roth, M., Zhong, B., Lan, X., Tian, J., He, Q., Li, D., Sun, J., Yang, X. and Lu, S. (2016) ‘Specific regulation of PRMT1 expression by PIAS1 and RKIP in BEAS-2B epithelia cells and HFL-1 fibroblasts in lung inflammation’, Sci Rep, 6, p. 21810. doi: 10.1038/srep21810.   edoc
Movassagh, H., Tatari, N., Shan, L., Koussih, L., Alsubait, D., Khattabi, M., Redhu, N. S., Roth, M., Tamm, M., Chakir, J. and Gounni, A. S. (2016) ‘Human airway smooth muscle cell proliferation from asthmatics is negatively regulated by semaphorin3A’, Oncotarget, 7(49), pp. 80238-80251. doi: 10.18632/oncotarget.12884.   edoc | Open Access
Papakonstantinou, E., Klagas, I., Roth, M., Tamm, M. and Stolz, D. (2016) ‘Acute Exacerbations of COPD Are Associated With Increased Expression of Heparan Sulfate and Chondroitin Sulfate in BAL’, Chest, 149(3), pp. 685-695. doi: 10.1378/chest.14-2868.   edoc
Seidel, P., Sun, Q., Costa, L., Lardinois, D., Tamm, M. and Roth, M. (2016) ‘The MNK-1/eIF4E pathway as a new therapeutic pathway to target inflammation and remodelling in asthma’, Cellular Signalling, 28(10), pp. 1555-1562. doi: 10.1016/j.cellsig.2016.07.004.   edoc
Sun, Q., Liu, L., Mandal, J., Molino, A., Stolz, D., Tamm, M., Lu, S. and Roth, M. (2016) ‘PDGF-BB induces PRMT1 expression through ERK1/2 dependent STAT1 activation and regulates remodeling in primary human lung fibroblasts’, Cellular Signalling, 28(4), pp. 307-315. doi: 10.1016/j.cellsig.2016.01.004.   edoc
Papakonstantinou, E., Karakiulakis, G., Batzios, S., Savic, S., Roth, M., Tamm, M. and Stolz, D. (2015) ‘Acute exacerbations of COPD are associated with significant activation of matrix metalloproteinase 9 irrespectively of airway obstruction, emphysema and infection’, Respiratory Research, 16, p. 78. doi: 10.1186/s12931-015-0240-4.   edoc
Papakonstantinou, E., Roth, M., Klagas, I., Karakiulakis, G., Tamm, M. and Stolz, D. (2015) ‘COPD Exacerbations Are Associated With Proinflammatory Degradation of Hyaluronic Acid’, Chest, 148(6), pp. 1497-1507. doi: 10.1378/chest.15-0153.   edoc
Roth, M. (2015) ‘Airway and lung remodelling in chronic pulmonary obstructive disease: a role for muscarinic receptor antagonists?’, Drugs, 75(1), pp. 1-8. doi: 10.1007/s40265-014-0319-0.   edoc
Roth, M., Zhao, F., Zhong, J., Lardinois, D. and Tamm, M. (2015) ‘Serum IgE Induced Airway Smooth Muscle Cell Remodeling Is Independent of Allergens and Is Prevented by Omalizumab’, PLoS One, 10(9), p. e0136549. doi: 10.1371/journal.pone.0136549.   edoc
Sun, Q., Liu, L., Roth, M., Tian, J., He, Q., Zhong, B., Bao, R., Lan, X., Jiang, C., Sun, J., Yang, X. and Lu, S. (2015) ‘PRMT1 Upregulated by Epithelial Proinflammatory Cytokines Participates in COX2 Expression in Fibroblasts and Chronic Antigen-Induced Pulmonary Inflammation’, The Journal of Immunology, 195(1), pp. 298-306. doi: 10.4049/jimmunol.1402465.   edoc
Zhao, F., Zhou, G., Ouyang, H., Liu, Y., Wang, A., Cai, L., Ti, X., Song, L., Shi, J., Wu, C., Chen, L., Roth, M. and Li, Z. (2015) ‘Association of the glucocorticoid receptor D641V variant with steroid-resistant asthma: a case-control study’, Pharmacogenetics and Genomics. Lippincott Williams & Wilkins, 25(6), pp. 289-295. doi: 10.1097/FPC.0000000000000130.   edoc
Mandal, J., Malla, B., Steffensen, R., Costa, L., Egli, A., Trendelenburg, M., Blasi, F., Kostikas, K., Welte, T., Torres, A., Louis, R., Boersma, W., Milenkovic, B., Aerts, J., Rohde, G. G., Lacoma, A., Rentsch, K., Roth, M., Tamm, M. and Stolz, D. (2015) ‘Mannose-binding lectin protein and its association to clinical outcomes in COPD: a longitudinal study’, Respir Res, 16, p. 150. doi: 10.1186/s12931-015-0306-3.   edoc | Open Access
Gazdhar, A., Lebrecht, D., Roth, M., Tamm, M., Venhoff, N., Foocharoen, C., Geiser, T. and Walker, U. A. (2014) ‘Time-dependent and somatically acquired mitochondrial DNA mutagenesis and respiratory chain dysfunction in a scleroderma model of lung fibrosis’, Scientific reports. Nature Publishing Group, 4, p. 5336. doi: 10.1038/srep05336.   edoc
Hostettler, K. E., Zhong, J., Papakonstantinou, E., Karakiulakis, G., Tamm, M., Seidel, P., Sun, Q., Mandal, J., Lardinois, D., Lambers, C. and Roth, M. (2014) ‘Anti-fibrotic effects of nintedanib in lung fibroblasts derived from patients with idiopathic pulmonary fibrosis’, Respiratory research. BioMed Central, 15(1), p. 157. doi: 10.1186/s12931-014-0157-3.   edoc
Lambers, C., Qi, Y., Eleni, P., Costa, L., Zhong, J., Tamm, M., Block, L. H. and Roth, M. (2014) ‘Extracellular matrix composition is modified by beta(2)-agonists through cAMP in COPD’, Biochemical Pharmacology. Elsevier, 91(3), pp. 400-408. doi: 10.1016/j.bcp.2014.07.026.   edoc
Zhong, J. and Roth, M. (2014) ‘Lung remodeling mechanisms in chronic lung diseases’, Current opinion in allergy and clinical immunology. Lippincott Williams & Wilkins, 14(1), pp. 69-76. doi: 10.1097/ACI.0000000000000022.   edoc
Costa, L., Roth, M., Miglino, N., Keglowich, L., Zhong, J., Lardinois, D., Tamm, M. and Borger, P. (2014) ‘Tiotropium sustains the anti-inflammatory action of olodaterol via the cyclic AMP pathway’, Pulmonary pharmacology & therapeutics. Elsevier, 27(1), pp. 29-37. doi: 10.1016/j.pupt.2013.11.001.   edoc
Movassagh, H., Shan, L., Halayko, A. J., Roth, M., Tamm, M., Chakir, J. and Gounni, A. S. (2014) ‘Neuronal chemorepellent Semaphorin 3E inhibits human airway smooth muscle cell proliferation and migration’, Journal of allergy and clinical immunology. Mosby, 133(2), pp. 560-567. doi: 10.1016/j.jaci.2013.06.011.   edoc
Hostettler, K. E., Halter, J. P., Gerull, S., Lardinois, D., Savic, S., Roth, M. and Tamm, M. (2014) ‘Calcineurin inhibitors in bronchiolitis obliterans syndrome following stem cell transplantation’, The European respiratory journal. Munksgaard, 43(1), pp. 221-232. doi: 10.1183/09031936.00199312.   edoc
Seidel, P. and Roth, M. (2013) ‘Anti-inflammatory dimethylfumarate : a potential new therapy for asthma?’, Mediators of inflammation. Hindawi Publishing Corp., 2013, ID 875403. doi: 10.1155/2013/875403.   edoc
Gazdhar, A., Susuri, N., Hostettler, K., Gugger, M., Knudsen, L., Roth, M., Ochs, M. and Geiser, T. (2013) ‘HGF Expressing Stem Cells in Usual Interstitial Pneumonia Originate from the Bone Marrow and Are Antifibrotic’, PLoS ONE. Public Library of Science, 8(6), p. e65453. doi: 10.1371/journal.pone.0065453.   edoc
Lambers, C., Roth, M., Zhong, J., Campregher, C., Binder, P., Burian, B., Petkov, V. and Block, L. H. (2013) ‘The interaction of endothelin-1 and TGF-beta1 mediates vascular cell remodeling’, PLoS ONE. Public Library of Science, Vol. 8, H. 8 , e73399. doi: 10.1371/journal.pone.0073399.   edoc
Roth, M., Zhong, J., Zumkeller, C., S’Ng C, T., Goulet, S. and Tamm, M. (2013) ‘The role of IgE-receptors in IgE-dependent airway smooth muscle cell remodelling’, PLoS ONE. Public Library of Science, 8(2). doi: 10.1371/journal.pone.0056015.   edoc
Rudiger, J. J., Gencay, M., Yang, J. Q., Bihl, M., Tamm, M. and Roth, M. (2013) ‘Fast beneficial systemic anti-inflammatory effects of inhaled budesonide and formoterol on circulating lymphocytes in asthma’, Respirology. Blackwell, 18(5), pp. 840-847. doi: 10.1111/resp.12104.   edoc
Kumawat, K., Menzen, M. H., Bos, I. S., Baarsma, H. A., Borger, P., Roth, M., Tamm, M., Halayko, A. J., Simoons, M., Prins, A., Postma, D. S., Schmidt, M. and Gosens, R. (2013) ‘Noncanonical WNT-5A signaling regulates TGF-beta-induced extracellular matrix production by airway smooth muscle cells’, The FASEB journal. FASEB, 27(4), pp. 1631-1643. doi: 10.1096/fj.12-217539.   edoc
Seidel, P., Hostettler, K. E., Hughes, J. M., Tamm, M. and Roth, M. (2013) ‘Dimethylfumarate inhibits CXCL10 via haem oxygenase-1 in airway smooth muscle’, The European respiratory journal. Munksgaard, 41(1), pp. 195-202. doi: 10.1183/09031936.00068411.   edoc
Karakiulakis, G. and Roth, M. (2012) ‘Muscarinic receptors and their antagonists in COPD: anti-inflammatory and antiremodeling effects’, Mediators of inflammation. Hindawi Publishing Corp., 2012, ID 409580. doi: 10.1155/2012/409580.   edoc
Papakonstantinou, E., Roth, M. and Karakiulakis, G. (2012) ‘Hyaluronic acid: A key molecule in skin aging’, Dermato-endocrinology. Landes Bioscience, 4(3), pp. 253-258. doi: 10.4161/derm.21923.   edoc
Miglino, N., Roth, M., Tamm, M. and Borger, P. (2012) ‘Asthma and COPD - The C/EBP Connection’, The open respiratory medicine journal. Bentham Open, Vol. 6, pp. 1-13. doi: 10.2174/1874306401206010001.   edoc
Papakonstantinou, E., Klagas, I., Karakiulakis, G., Hostettler, K., S’Ng C, T., Kotoula, V., Savic, S., Tamm, M. and Roth, M. (2012) ‘Steroids and beta2-agonists regulate hyaluronan metabolism in asthmatic airway smooth muscle cells’, American journal of respiratory cell and molecular biology. American Thoracic Society, 47(6), pp. 759-767. doi: 10.1165/rcmb.2012-0101OC.   edoc
Miglino, N., Roth, M., Lardinois, D., Sadowski, C., Tamm, M. and Borger, P. (2012) ‘Cigarette smoke inhibits lung fibroblast proliferation by translational mechanisms’, The European respiratory journal. Munksgaard, 39(3), pp. 705-711. doi: 10.1183/09031936.00174310.   edoc
Miglino, N., Roth, M., Baty, F., Brutsche, M., Tamm, M. and Borger, P. (2012) ‘Asthma and the regulated retrotransposon transcriptome’, The European respiratory journal. Munksgaard, 40(3), pp. 788-790. doi: 10.1183/09031936.00189811.   edoc
Miglino, N., Roth, M., Lardinois, D., Tamm, M. and Borger, P. (2012) ‘Calreticulin is a negative regulator of bronchial smooth muscle cell proliferation’, Journal of allergy. Hindawi, Vol. 2012, 783290. doi: 10.1155/2012/783290.   edoc
Roth, M. (2011) ‘Is there a regulatory role of immunoglobulins on tissue forming cells relevant in chronic inflammatory lung diseases?’, Journal of allergy. Hindawi, Vol. 2011, p. 721517. doi: 10.1155/2011/721517.   edoc
Seidel, P., Roth, M., Ge, Q., Merfort, I., S’Ng C, T. and Ammit, A. J. (2011) ‘IκBα glutathionylation and reduced histone H3 phosphorylation inhibit eotaxin and RANTES’, The European respiratory journal. Munksgaard, 38(6), pp. 1444-1452. doi: 10.1183/09031936.00129610.   edoc
Miglino, N., Roth, M., Tamm, M. and Borger, P. (2011) ‘House dust mite extract downregulates C/EBPα in asthmatic bronchial smooth muscle cells’, The European respiratory journal. Munksgaard, 38(1), pp. 50-58. doi: 10.1183/09031936.00068010.   edoc
Brellier, F., Hostettler, K., Hotz, H.-R., Ozcakir, C., Çöloğlu, S. A., Togbe, D., Ryffel, B., Roth, M. and Chiquet-Ehrismann, R. (2011) ‘Tenascin-C triggers fibrin accumulation by downregulation of tissue plasminogen activator’, FEBS Letters. Elsevier, 585(6), pp. 913-920. doi: 10.1016/j.febslet.2011.02.023.   edoc
Zhong, J., Lardinois, D., Szilard, J., Tamm, M. and Roth, M. (2011) ‘Rat mesothelioma cell proliferation requires p38δ mitogen activated protein kinase and C/EBP-α’, Lung cancer. Elsevier, 73(2), pp. 166-170. doi: 10.1016/j.lungcan.2010.12.003.   edoc
Roth, M. and Tamm, M. (2010) ‘Airway smooth muscle cells respond directly to inhaled environmental factors’, Swiss medical weekly, Vol. 140 , w13066.   edoc
Roth, M. and Tamm, M. (2010) ‘The effects of omalizumab on IgE-induced cytokine synthesis by asthmatic airway smooth muscle cells’, Annals of allergy, asthma, and immunology. ACAAI, 104(2), pp. 152-160. doi: 10.1016/j.anai.2009.11.022.   edoc
Seidel, P., Goulet, S., Hostettler, K., Tamm, M. and Roth, M. (2010) ‘DMF inhibits PDGF-BB induced airway smooth muscle cell proliferation through induction of heme-oxygenase-1’, Respiratory research. BioMed Central, Vol. 11, p. 145. doi: 10.1186/1465-9921-11-145.   edoc
Seidel, P., Merfort, I., Tamm, M. and Roth, M. (2010) ‘Inhibition of NF- B and AP-1 by dimethylfumarate correlates with down-regulated IL-6 secretion and proliferation in human lung fibroblasts’, Swiss medical weekly. EMH, Vol. 140 , w13132.   edoc
Gencay, M., Roth, M., Christ-Crain, M., Mueller, B., Tamm, M. and Stolz, D. (2010) ‘Single and multiple viral infections in lower respiratory tract infection’, Respiration. Karger, 80(6), pp. 560-567. doi: 10.1159/000321355.   edoc | Open Access