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The laboratory of Marc Donath and collaborators have revealed a signalling pathway in pancreatic immune cells
The laboratory of Marc Donath and collaborators have revealed a signalling pathway in pancreatic immune cells, which is is stimulating insulin secretion in pancreatic beta cells.
Because this mechanism is impaired in obese patients, selective activation of this pathway could offer new therapeutic avenues for the treatment of diabetes. Their discovery as recently published in Immunity