News

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Welcome to the Team – Felix Mahfoud Lab!

Prof. Felix Mahfoud has been appointed Professor of Cardiology at the University of Basel and Chief of Cardiology at the University Hospital Basel. He is also Chairman of the University Heart Center Basel. His research at the DBM focuses on…
Loss of presynaptic GABAB receptors in Ajap1-/- mice. Immunolabeling of AJAP1 and presynaptic GABAB1a (GB1a) protein in the hilus region of the hippocampus of Ajap1-/- and Ajap1+/+ mice.  Presynaptic GABAB receptors are lost in the absence of AJAP1 protein.

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Discovery of a new mechanism involving GABA-B receptors and the protein AJAP-1 in the localization of these receptors in the brain (Bettler Lab)

The DBM congratulates the Bettler Lab for their recent paper accepted by Science Advances. The authors have uncovered a novel mechanism involving GABA-B receptors and the protein AJAP-1, which maintains the receptors' placement in the…
Immunofluorescent image of the DG from Safb cKO mice stained with antibodies against GFP and NFIB and counter stained with DAPI. GFP expressing cells are Hes5::CreERT2-expressing NSC and their progeny.

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New study provides novel insight into molecular mechanisms regulating neural stem cell fate (Taylor Lab)

Adult murine brains and their neural stem cells (NSCs) from the hippocampus are thoroughly guided to either renew themselves or differentiate into neurons and astrocytes. However, unlike NSCs from the subventricular zone, they do not…
Newsletter Issue 07

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Department of Biomedicine Newsletter No. 7

We are pleased to announce the release of the seventh edition of our DBM Newsletter. We hope you enjoy reading it!
New approach to Epstein-Barr virus and resulting diseases

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New Approach to Epstein-Barr Virus and Resulting Diseases (Hess Lab)

The Epstein-Barr virus can cause a spectrum of diseases, including a range of cancers. Emerging data now show that inhibition of a specific metabolic pathway in infected cells can diminish latent infection and therefore the risk of…