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Interferon-γ resistance and immune evasion in glioma develop via Notch-regulated co-evolution of malignant and immune cells (Taylor Lab)
Gliomas are aggressive brain tumors and resistant to current standard and targeted therapeutic interventions. Immune evasion is pronounced in glioma, but the underlying mechanisms remain poorly understood. Parmigiani et al. demonstrate that…
The Right Environment for Fighting Cancer (Zippelius Lab)
Cancer immunotherapy is a successful form of treatment in oncology, but it doesn't work for every patient. One problem may be the lack of a specific type of immune cell in the tumor, researchers in the Department of Biomedicine at the…
The national MD-PhD commission has awarded a grant to Deniz Kaymak and Lukas Kübler
Out of the 22 candidates proposed by the local MD-PhD commissions at the five university hospitals, the national MD-PhD commission has awarded a grant to 13 young doctors who are interested in doing research.
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Promising Therapeutic Strategy Against Glioblastoma (Hutter Lab)
Glioblastoma (GBM) is a lethal brain tumor without effective treatment options. Despite multimodal therapy including surgery, radiation and alkylating chemotherapy, tumors recur swiftly and are resistant to further treatments. In order to…