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Carolyn King’s research group shows that specialized helper cells contribute to immunological memory

Marko Künzli, David Schreiner, and collaborators from Basel, Cambridge and the US demonstrated in a recent article published in Science Immunology that T follicular helper cells (Tfh) live much longer than previously thought and contribute...
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Nicola Aceto receives Friedrich Miescher Award 2020

The DBM congratulates Prof. Nicola Aceto, research group leader of the Cancer Metastasis research group, with this achievement for his research on circulating tumor cell clusters. The Friedrich Miescher Award honors Swiss or Swiss-based...
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The European Research Council awards Claudia Lengerke an ERC Consolidator Grant

With nearly 2 million Euro, Claudia Lengerke and her team will investigate how leukemia stem cells can be more efficiently targeted. This is the first individual ERC Grant for a clinical professorship at the University of Basel. Uni News
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/ Research

National Center of Competence in Research (NCCR): “AntiResist”

Basel will host the new NCCR that focuses on novel approaches to combat antibiotic-resistant bacteria. Prof. Nina Khanna and Prof. Adrian Egli from the Department of Biomedicine and University Hospital will have a leading role in the...
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Tanja Rinaldi Barkat’s research group shows white noise improves hearing

In collaboration with researchers from the University of Copenhagen, Rasmus Kordt Christensen and colleagues revealed that hearing pure sounds becomes more precise with a background of continuous white noise, better than in a quiet...
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Jürg Schwaller and collaborators explain why some forms of leukemia develop only in infants. (Journal of Cancer Discovery)

Why some forms of leukemia only affect children
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Autoimmunkrankheiten: Basel ist wichtiger Partner bei grosser europäischer Forschungsoffensive

Autoimmune, entzündliche und allergische Erkrankungen sind verbreitete chronische Erkrankungen, die das Leben von Millionen Menschen in aller Welt beeinträchtigen. Sie sind auch ein signifikanter Faktor bei den Gesundheitskosten. Nun will...
Kashyap Cell Reports 2019

/ News, Research

Members of the Zippelius lab and collaborators revealed how microtubule destabilitzing chemotherapy promotes protective anti-tumor immunity.

In collaboration with researchers from Massachusetts General Hospital and Harvard Medical School, Abhishek Kashyap and colleagues found that microtubule destabilization in dendritic cells results in the release of the guanine nucleotide...
SDHA-SDHB

/ News, Research

The Hess and Recher labs identify the disease mechanism of a hitherto unknown primary antibody defciency

The researchers identified a gain-of-function mutation in the metabolic enzyme SDHA, which leads to an accumulation of fumarate and causes inflamatory mitochondrial retrograde signaling as a disease modifier in primary antibody...
The image depicts Id4 (blue) and GFAP (black) expression in genetically labeled stem cells and their progeny (magenta) in the hippocampus of the mouse brain. The image presents an artistic coloration of the spatial and molecular factors in a niche. (Image: University of Basel)

/ News, Research

Verdon Taylor and collaborators identified a signalling pathway that maintains neural stem cell quiescence in adult mouse brain

In their study that was recently published in Cell Reports they discovered a central role fot the Notch2 effector Id4. Id4 not only blocks cell cycle entry but also promotes astrocytic differentiation of hippocampal neural stem cells. ...