Publications
Honeycutt, D. et al. (2024) “Letter to the editor: fasting decreases expression of microRNAs linked to endothelial pathophysiology in mononuclear cells of healthy subjects”, Apoptosis, 29(7-8), pp. 935–937. Available at: 10.1007/s10495-024-01971-4.
Kropfl, J. et al. (2022) “Lymphocytes are less sensitive to autophagy than monocytes during fasting and exercise conditions”, Apoptosis, 27(9-10), pp. 730–739. Available at: 10.1007/s10495-022-01752-x.
Isu, G. et al. (2020) “Fatty acid-based monolayer culture to promote in vitro neonatal rat cardiomyocyte maturation”, Biochimica et Biophysica Acta - Molecular Cell Research, 1867(3). Available at: 10.1016/j.bbamcr.2019.118561.
Heim, P. et al. (2020) “Neuregulin-1 triggers GLUT4 translocation and enhances glucose uptake independently of insulin receptor substrate and ErbB3 in neonatal rat cardiomyocytes”, Biochimica et Biophysica Acta - Molecular Cell Research, 1867(3), p. 118562. Available at: 10.1016/j.bbamcr.2019.118562.
Brink, M., Zuppinger, C. (2020) “9th Ascona International Workshop on Cardiomyocyte Biology”. Available at: 10.1016/j.bbamcr.2019.118618.
De, K.G. et al. (2019) “Mechanisms of the Multitasking Endothelial Protein NRG-1 as a Compensatory Factor during Chronic Heart Failure”, Circulation: Heart Failure, 12(10). Available at: 10.1161/circheartfailure.119.006288.
Whitehead, N. et al. (2018) “Moderate Modulation of Cardiac PGC-1α Expression Partially Affects Age-Associated Transcriptional Remodeling of the Heart”, Frontiers in Physiology, 9, p. 242. Available at: 10.3389/fphys.2018.00242. edoc | Open Access
Pentassuglia, L. et al. (2016) “Neuregulin-1β promotes glucose uptake via PI3K/Akt in neonatal rat cardiomyocytes”, American Journal of Physiology - Endocrinology and Metabolism, 310(9), pp. E782-E794. Available at: 10.1152/ajpendo.00259.2015.
Shende, P. et al. (2016) “Cardiac mTOR complex 2 preserves ventricular function in pressure-overload hypertrophy”, Cardiovascular Research, 109(1), pp. 103–114. Available at: 10.1093/cvr/cvv252. edoc | Open Access
Xu, L., Brink, M. (2016) “mTOR, cardiomyocytes and inflammation in cardiac hypertrophy”, Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1863(7 Pt B), pp. 1894–903. Available at: 10.1016/j.bbamcr.2016.01.003. edoc
Lopez, R.J. et al. (2016) “An RYR1 mutation associated with malignant hyperthermia is also associated with bleeding abnormalities”, Science Signaling, 9(435), p. ra68. Available at: 10.1126/scisignal.aad9813. edoc | Open Access
Pentassuglia, L. et al. (2016) “Neuregulin-1β promotes glucose uptake via PI3K/Akt in neonatal rat cardiomyocytes”, American Journal of Physiology: Endocrinology and Metabolism, 310(9), pp. E782–94. Available at: 10.1152/ajpendo.00259.2015. edoc
Gosselin-Badaroudine, P. et al. (2012) “A proton leak current through the cardiac sodium channel is linked to mixed arrhythmia and the dilated cardiomyopathy phenotype”, PLoS ONE, 7(5). Available at: 10.1371/journal.pone.0038331.
Brink, M., Nicholls, M. (2011) “Spotlight: Marijke Brink, PhD”. LIPPINCOTT WILLIAMS & WILKINS.
Brink, M. (2011) “Team 2011: Professor Brink’s Team, Department of Biomedicine, University Hospital Basel, Basel, Switzerland”. LIPPINCOTT WILLIAMS & WILKINS.
Shende, P. et al. (2011) “Cardiac raptor ablation impairs adaptive hypertrophy, alters metabolic gene expression, and causes heart failure in mice”, Circulation, 123(10), pp. 1073–82. Available at: 10.1161/circulationaha.110.977066. edoc
Häuselmann, S.P. et al. (2011) “β1-Integrin is up-regulated via Rac1-dependent reactive oxygen species as part of the hypertrophic cardiomyocyte response”, Free radical biology & medicine, 51(3), pp. 609–18. Available at: 10.1016/j.freeradbiomed.2011.05.007. edoc
Grussenmeyer, T. et al. (2011) “Proteome analysis in cardiovascular pathophysiology using Dahl rat model”, Journal of proteomics, 74(5), pp. 672–82. Available at: 10.1016/j.jprot.2011.02.015. edoc
Meili-Butz, S. et al. (2010) “Acute effects of urocortin 2 on cardiac function and propensity for arrhythmias in an animal model of hypertension-induced left ventricular hypertrophy and heart failure”, European journal of heart failure, 12(8), pp. 797–804. Available at: 10.1093/eurjhf/hfq054. edoc
Meili-Butz, S. et al. (2009) “Chronic Administration of Urocortin 2 in Hypertension-Induced Hypertrophy: Effects on Intracellular Calcium Handling and Hemodynamics”. LIPPINCOTT WILLIAMS & WILKINS.
Bühler, K. et al. (2009) “The human urocortin 2 gene is regulated by hypoxia : identification of a hypoxia-responsive element in the 3’-flanking region”, Biochemical journal : BJ, 424(1), pp. 119–27. Available at: 10.1042/bj20090311. edoc
Keller, D.I. et al. (2009) “Characterization of novel KCNH2 mutations in type 2 long QT syndrome manifesting as seizures”, The Canadian journal of cardiology = Journal canadien de cardiologie, 25(8), pp. 455–62. Available at: 10.1016/s0828-282x(09)70117-5. edoc
Dieterle, T. et al. (2009) “Immediate and sustained blood pressure lowering by urocortin 2 : a novel approach to antihypertensive therapy?”, Hypertension, 53(4), pp. 739–44. Available at: 10.1161/hypertensionaha.108.125211. edoc
Meill-Butz, S. et al. (2008) “Chronic Administration of Urocortln 2 Prevents the Development of Heart Failure In an Animal Model of Hypertensive Heart Disease”. LIPPINCOTT WILLIAMS & WILKINS.
Plaisance, I., Morandi, C., Brink, M. (2008) “IGF-I-induced AKT activation abolishes TNF-alpha/p38-mediated increases in atrogin-1 gene expression in muscle”. ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD. Available at: 10.1016/j.yjmcc.2008.02.258.
Meili-Butz, S. et al. (2008) “Dimethyl fumarate, a small molecule drug for psoriasis, inhibits Nuclear Factor-kappaB and reduces myocardial infarct size in rats”, European Journal of Pharmacology, 586(1-3), pp. 251–8. Available at: 10.1016/j.ejphar.2008.02.038. edoc
Plaisance, I. et al. (2008) “TNF-alpha increases protein content in C2C12 and primary myotubes by enhancing protein translation via the TNF-R1, PI3K, and MEK”, American journal of physiology. Endocrinology and metabolism, 294(2), pp. E241–50. Available at: 10.1152/ajpendo.00129.2007. edoc
Bentzinger, C.F. et al. (2008) “Skeletal muscle-specific ablation of raptor, but not of rictor, causes metabolic changes and results in muscle dystrophy”, Cell Metabolism, 8(5), pp. 411–24. Available at: 10.1016/j.cmet.2008.10.002. edoc
Dieterle, T. et al. (2007) “Immediate and sustained blood pressure lowering by CRF-receptor stimulation: A novel approach to anti hypertensive therapy?”. LIPPINCOTT WILLIAMS & WILKINS.
Plaisance, I. et al. (2007) “IGF-1 prevents TNF-alpha-induced atrogin-1 gene expression in C2C12 myotubes”. ELSEVIER SCIENCE BV.
Keller, D. et al. (2006) “A novel SCN5A mutation, F1344S, identified in a patient with Brugada syndrome and fever-induced ventricular fibrillation”, Cardiovascular Research, 70(3), pp. 521–529. Available at: 10.1016/j.cardiores.2006.02.030.
Keller, D. et al. (2005) “A novel nonsense mutation in the SCN5A gene leads to Brugada syndrome and a silent gene mutation carrier state”, Canadian Journal of Cardiology, 21(11), pp. 925–931.
Brink, M. (2005) “The Ubiquitin-Proteasome Pathway”, in, pp. 511–542.
Delafontaine, P., Brink, M., H Song, Y. (2004) “Mechanisms of cardiac hypertrophy and the development of heart failure - Role of insulin-like growth factor-I and angiotensin II”, in Human Press Inc., Totowa, NJ, pp. 311–329.
Myit, S. et al. (2003) “Different growth properties of neointimal and medial smooth muscle cells in response to growth factors”, Journal of Vascular Research, 40(2), pp. 97–104. Available at: 10.1159/000070706.
Anwar, A. et al. (2002) “Effect of congestive heart failure on the insulin-like growth factor-1 system”, American Journal of Cardiology, 90(12), pp. 1402–1405. Available at: 10.1016/S0002-9149(02)02885-0.
Brink, M., Anwar, A., Delafontaine, P. (2002) “Neurohormonal factors in the development of catabolic/anabolic imbalance and cachexia”, International Journal of Cardiology, 85(1), pp. 111–121. Available at: 10.1016/S0167-5273(02)00239-5.
Anwar, A. et al. (2002) “Tumor necrosis factor-α regulates insulin-like growth factor-1 and insulin-like growth factor binding protein-3 expression in vascular smooth muscle”, Circulation, 105(10), pp. 1220–1225. Available at: 10.1161/hc1002.105187.
Du, J. et al. (2001) “Thrombin regulates insulin-like growth factor-1 receptor transcription in vascular smooth muscle characterization of the signaling pathway”, Circulation Research, 88(10), pp. 1044–1052. Available at: 10.1161/hh1001.090840.
Giraud, S. et al. (2001) “Translation Initiation of the Insulin-like Growth Factor I Receptor mRNA Is Mediated by an Internal Ribosome Entry Site”, Journal of Biological Chemistry, 276(8), pp. 5668–5675. Available at: 10.1074/jbc.M005928200.
Brink, M. et al. (2001) “Angiotensin II induces skeletal muscle wasting through enhanced protein degradation and down-regulates autocrine insulin-like growth factor I”, Endocrinology, 142(4), pp. 1489–1496. Available at: 10.1210/endo.142.4.8082.
Okura, Y. et al. (2001) “Decreased expression of insulin-like growth factor-1 and apoptosis of vascular smooth muscle cells in human atherosclerotic plaque”, Journal of Molecular and Cellular Cardiology, 33(10), pp. 1777–1789. Available at: 10.1006/jmcc.2001.1441.
Okura, Y. et al. (2000) “Oxidized low-density lipoprotein is associated with apoptosis of vascular smooth muscle cells in human atherosclerotic plaques”, Circulation, 102(22), pp. 2680–2686. Available at: 10.1161/01.CIR.102.22.2680.
Delafontaine, P., Brink, M. (2000) “The growth hormone and insulin-like growth factor 1 axis in heart failure”, Annales d’Endocrinologie, 61(1), pp. 22–26.
Freudenthaler, S. et al. (2000) “Dose-dependent effect of angiotensin II on human erythropoietin production”, Pflugers Archiv European Journal of Physiology, 439(6), pp. 838–844. Available at: 10.1007/s004249900238.
Delafontaine, P. et al. (1999) “Growth factors and receptors in allograft arteriosclerosis”, Transplantation Proceedings, 31(1-2), pp. 111–114. Available at: 10.1016/S0041-1345(98)01464-X.
Brink, M. et al. (1999) “Angiotensin II stimulates gene expression of cardiac insulin-like growth factor I and its receptor through effects on blood pressure and food intake”, Hypertension, 34(5), pp. 1053–1059. Available at: 10.1161/01.HYP.34.5.1053.
Brink, M., Wellen, J., Delafontaine, P. (1996) “Angiotensin II causes weight loss and decreases circulating insulin-like growth factor I in rats through a pressor-independent mechanism”, Journal of Clinical Investigation, 97(11), pp. 2509–2516. Available at: 10.1172/JCI118698.
Brink, M. et al. (1996) “Localization of the angiotensin II receptor subtypes in the human atrium”, Journal of Molecular and Cellular Cardiology, 28(8), pp. 1789–1799. Available at: 10.1006/jmcc.1996.0168.
Delafontaine, P., Brink, M., Du, J. (1996) “Angiotensin II modulation of insulin-like growth factor I expression in the cardiovascular system”, Trends in Cardiovascular Medicine, 6(6), pp. 187–193. Available at: 10.1016/s1050-1738(96)00058-8.
Brink, M. et al. (1995) “Localization of angiotensin II receptor subtypes in the rabbit heart”, Journal of Molecular and Cellular Cardiology, 27(1), pp. 459–470. Available at: 10.1016/S0022-2828(08)80042-9.
van, S.B. et al. (1995) “Localization of the glucocorticoid receptor in discrete clusters in the cell nucleus”, Journal of Cell Science, 108(9), pp. 3003–3011. Available at: 10.1242/jcs.108.9.3003.
de, G.M. et al. (1994) “Angiotensin II receptor subtypes and cardiac function”, European Heart Journal, 15(SUPPL. D), pp. 98–103. Available at: 10.1093/eurheartj/15.suppl_d.98.
Brink, M. et al. (1992) “The unliganded glucocorticoid receptor is localized in the nucleus, not in the cytoplasm”, Endocrinology, 130(6), pp. 3575–3581. Available at: 10.1210/endo.130.6.1597154.
Brink, M. et al. (1990) “A Dictyostelium mutant lacking an F-actin cross-linking protein, the 120-kD gelation factor”, Journal of Cell Biology, 111(4), pp. 1477–1489. Available at: 10.1083/jcb.111.4.1477.
André, E. et al. (1989) “A Dictyostelium mutant deficient in severin, an F-actin fragmenting protein, shows normal motility and chemotaxis”., The Journal of cell biology, 108(3), pp. 985–995. Available at: 10.1083/jcb.108.3.985.
Schleicher, M. et al. (1988) “A Dictyostelium mutant with severe defects in alpha-actinin: its characterization using cDNA probes and monoclonal antibodies”., Journal of cell science, 90 ( Pt 1), pp. 59–71. Available at: 10.1242/jcs.90.1.59.
van, P.-V.E. et al. (1986) “Time course of arterial repair following endothelial denudation in the rat carotid artery - A morphometric study in Wistar and Sprague-Dawley rats”, Virchows Archiv A Pathological Anatomy and Histopathology, 408(6), pp. 559–574. Available at: 10.1007/BF00705336.
Claviez, M., Brink, M., Gerisch, G. (1986) “Cytoskeletons from a mutant of Dictyostelium discoideum with flattened cells”., Journal of cell science, 86, pp. 69–82. Available at: 10.1242/jcs.86.1.69.