Publications
Falcetta, D. et al. (2024) “CaMKIIβ deregulation contributes to neuromuscular junction destabilization in Myotonic Dystrophy type I”, Skeletal Muscle, 14(1). Available at: 10.1186/s13395-024-00345-3.
Müller-Durovic, B. et al. (2024) “A metabolic dependency of EBV can be targeted to hinder B cell transformation”, Science (New York, N.Y.), 385, p. eadk4898. Available at: 10.1126/science.adk4898.
Mainardi, A. et al. (2023) “Modelling Osteoarthritis pathogenesis through Mechanical Loading in an Osteochondral Unit-on-Chip”. Cold Spring Harbor Laboratory. Available at: 10.1101/2023.08.29.555292.
Couto, J.P. et al. (2023) “Nicotinamide N-methyltransferase sustains a core epigenetic program that promotes metastatic colonization in breast cancer”, EMBO Journal, 42(13). Available at: 10.15252/embj.2022112559.
Piqué-Borràs, M.-R. et al. (2023) “The NFIA-ETO2 fusion blocks erythroid maturation and induces pure erythroid leukemia in cooperation with mutant TP53”, Blood, 141(18), pp. 2245–2260. Available at: 10.1182/blood.2022017273.
Rodrigues, P.F. et al. (2023) “pDC-like cells are pre-DC2 and require KLF4 to control homeostatic CD4 T cells”, Science Immunology, 8(80). Available at: 10.1126/sciimmunol.add4132.
Wang, J. et al. (2022) “Siglec Receptors Modulate Dendritic Cell Activation and Antigen Presentation to T Cells in Cancer”, Frontiers in Cell and Developmental Biology, 10. Available at: 10.3389/fcell.2022.828916.
Lett, M.J. et al. (2022) “Stimulatory MAIT cell antigens reach the circulation and are efficiently metabolised and presented by human liver cells”, Gut, 71(12), pp. 2526–2538. Available at: 10.1136/gutjnl-2021-324478.
Parmigiani, E. et al. (2022) “Interferon-γ resistance and immune evasion in glioma develop via Notch-regulated co-evolution of malignant and immune cells”, Developmental Cell, 57, pp. 1847–1865.e9. Available at: 10.1016/j.devcel.2022.06.006.
Lüönd, F. et al. (2021) “Distinct contributions of partial and full EMT to breast cancer malignancy”, Developmental Cell, 56(23), pp. 3203–3221.e11. Available at: 10.1016/j.devcel.2021.11.006.
Saxena, M. et al. (2021) “The long non-coding RNA ET-20 mediates EMT by impairing desmosomes in breast cancer cells”, Journal of Cell Science, 134(21). Available at: 10.1242/jcs.258418.
Leonards, K. et al. (2020) “Nuclear interacting SET domain protein 1 inactivation impairs GATA1-regulated erythroid differentiation and causes erythroleukemia”, Nature Communications, 11(1), p. 2807. Available at: 10.1038/s41467-020-16179-8.
Lehmann, F. et al. (2020) “Microbiota-induced tissue signals regulate ILC3-mediated antigen presentation”, Nature Communications, 11(1), p. 1794. Available at: 10.1038/s41467-020-15612-2.
Meyer-Schaller, N. et al. (2020) “A dual role of Irf1 in maintaining epithelial identity but also enabling EMT and metastasis formation of breast cancer cells”, Oncogene, 39(24), pp. 4728–4740. Available at: 10.1038/s41388-020-1326-0.
Reinhardt, R. et al. (2019) “Molecular signatures identify immature mesenchymal progenitors in early mouse limb buds that respond differentially to morphogen signaling”, Development (Cambridge), 146(10). Available at: 10.1242/dev.173328.
Meyer-Schaller, N. et al. (2019) “A Hierarchical Regulatory Landscape during the Multiple Stages of EMT”, Developmental Cell, 48(4), pp. 539–553.e6. Available at: 10.1016/j.devcel.2018.12.023.
Ishay-Ronen, D. et al. (2019) “Gain Fat—Lose Metastasis: Converting Invasive Breast Cancer Cells into Adipocytes Inhibits Cancer Metastasis”, Cancer Cell, 35(1), pp. 17–32.e6. Available at: 10.1016/j.ccell.2018.12.002.
Burgener, A.-V. et al. (2019) “SDHA gain-of-function engages inflammatory mitochondrial retrograde signaling via KEAP1-Nrf2”, Nature Immunology, 20(10), pp. 1311–1321. Available at: 10.1038/s41590-019-0482-2. edoc
Tiede, S. et al. (2018) “The FAK inhibitor BI 853520 exerts anti-tumor effects in breast cancer”., Oncogenesis, 7(9), p. 73. Available at: 10.1038/s41389-018-0083-1.
Drobek, A. et al. (2018) “Strong homeostatic TCR signals induce formation of self-tolerant virtual memory CD8 T cells”., The EMBO journal, 37(14). Available at: 10.15252/embj.201798518.
Rodrigues, P. et al. (2018) “Distinct progenitor lineages contribute to the heterogeneity of plasmacytoid dendritic cells”., Nature immunology, 19(7), pp. 711–722. Available at: 10.1038/s41590-018-0136-9.
Raykova, A. et al. (2017) “Interleukins 12 and 15 induce cytotoxicity and early NK-cell differentiation in type 3 innate lymphoid cells”, Blood Advances, 1(27), pp. 2679–2691. Available at: 10.1182/bloodadvances.2017008839.
Alberti-Servera, L. et al. (2017) “Single-cell RNA sequencing reveals developmental heterogeneity among early lymphoid progenitors”., The EMBO journal, 36(24), pp. 3619–3633. Available at: 10.15252/embj.201797105.
Däster, S. et al. (2017) “Induction of hypoxia and necrosis in multicellular tumor spheroids is associated with resistance to chemotherapy treatment”, Oncotarget, 8(1), pp. 1725–1736. Available at: 10.18632/oncotarget.13857. edoc
Mochizuki, M. et al. (2017) “Polo-Like Kinase 2 is Dynamically Regulated to Coordinate Proliferation and Early Lineage Specification Downstream of Yes-Associated Protein 1 in Cardiac Progenitor Cells”, Journal of the American Heart Association, 6(10), p. e005920. Available at: 10.1161/jaha.117.005920. edoc
Diepenbruck, M. et al. (2017) “miR-1199-5p and Zeb1 function in a double-negative feedback loop potentially coordinating EMT and tumour metastasis”, Nature Communications, 8(1), p. 1168. Available at: 10.1038/s41467-017-01197-w. edoc
Thakurela, S. et al. (2016) “Mapping gene regulatory circuitry of Pax6 during neurogenesis”., Cell discovery, 2, p. 15045. Available at: 10.1038/celldisc.2015.45.
Hahne, F., Ivanek, R. (2016) “Visualizing Genomic Data Using Gviz and Bioconductor”., Methods in molecular biology (Clifton, N.J.), 1418, pp. 335–51. Available at: 10.1007/978-1-4939-3578-9_16.
Swiss Institute of Bioinformatics Members, S., Swiss Institute of Bioinformatics Members, S. (2016) “The SIB Swiss Institute of Bioinformatics’ resources: focus on curated databases”, Nucleic acids research, 44(D1), pp. D27-D37. Available at: 10.1093/nar/gkv1310. edoc | Open Access
Moretti, F. et al. (2015) “Growth Cone Localization of the mRNA Encoding the Chromatin Regulator HMGN5 Modulates Neurite Outgrowth”, Molecular and Cellular Biology, 35(11), pp. 2035–50. Available at: 10.1128/mcb.00133-15. edoc
Fagiani, E. et al. (2015) “An immature B cell population from peripheral blood serves as surrogate marker for monitoring tumor angiogenesis and anti-angiogenic therapy in mouse models”, Angiogenesis, 18(3), pp. 327–345. Available at: 10.1007/s10456-015-9470-9. edoc
Giachino, C. et al. (2015) “A tumor suppressor function for Notch signaling in forebrain tumor subtypes”, Cancer Cell, 28(6), pp. 730–742. Available at: 10.1016/j.ccell.2015.10.008. edoc
Hirt, C. et al. (2015) “Bioreactor-engineered cancer tissue-like structures mimic phenotypes, gene expression profiles and drug resistance patterns observed ‘in vivo’”, Biomaterials, 62, pp. 138–146. Available at: 10.1016/j.biomaterials.2015.05.037. edoc
Vigano, M.A. et al. (2014) “An epigenetic profile of early T-cell development from multipotent progenitors to committed T-cell descendants”., European journal of immunology, 44(4), pp. 1181–93. Available at: 10.1002/eji.201344022. edoc
Lopez-Rios, J. et al. (2014) “Attenuated sensing of SHH by Ptch1 underlies evolution of bovine limbs”, Nature, 511(7507), pp. 46–51. Available at: 10.1038/nature13289. edoc
Diepenbruck, M. et al. (2014) “Tead2 expression levels control the subcellular distribution of Yap and Taz, zyxin expression and epithelial-mesenchymal transition”, Journal of Cell Science, 127(Pt 7), pp. 1523–36. Available at: 10.1242/jcs.139865. edoc | Open Access
Osterwalder, M. et al. (2014) “HAND2 targets define a network of transcriptional regulators that compartmentalize the early limb bud mesenchyme”, Developmental Cell, 31(3), pp. 345–357. Available at: 10.1016/j.devcel.2014.09.018. edoc
Baubec, T. et al. (2013) “Methylation-dependent and -independent genomic targeting principles of the MBD protein family”., Cell, 153(2), pp. 480–92. Available at: 10.1016/j.cell.2013.03.011.
Molinsky, J. et al. (2013) “Roscovitine sensitizes leukemia and lymphoma cells to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis”, Leukemia and Lymphoma, 54(2), pp. 372–380. Available at: 10.3109/10428194.2012.710331.
Dertschnig, S. et al. (2013) “Epithelial cytoprotection sustains ectopic expression of tissue-restricted antigens in the thymus during murine acute GVHD”, Blood, 122(5), pp. 837–41. Available at: 10.1182/blood-2012-12-474759. edoc
Feldmann, A. et al. (2013) “Transcription factor occupancy can mediate active turnover of DNA methylation at regulatory regions”., PLoS genetics, 9(12), p. e1003994. Available at: 10.1371/journal.pgen.1003994.
Stadler, M.B. et al. (2012) “Erratum: DNA-binding factors shape the mouse methylome at distal regulatory regions (Nature (2011) 480 (490-495))”, Nature, 484(7395). Available at: 10.1038/nature11086.
Tippmann, S.C. et al. (2012) “Chromatin measurements reveal contributions of synthesis and decay to steady-state mRNA levels”, Molecular systems biology, 8, p. 593. Available at: 10.1038/msb.2012.23. edoc
Homolka, D. et al. (2011) “Differential expression of non-coding rnas and continuous evolution of the x chromosome in testicular transcriptome of two mouse species”, PLoS ONE, 6(2). Available at: 10.1371/journal.pone.0017198.
Stadler, M.B. et al. (2011) “DNA-binding factors shape the mouse methylome at distal regulatory regions”, Nature, 480(7378), pp. 490–5. Available at: 10.1038/nature10716. edoc
Homolka, D. et al. (2010) “Comparison of testicular transcriptome between two mouse species shows dysregulation of protein-non-coding RNAs and confirms continuous evolution of the X chromosome”, New Biotechnology, 27, p. S52. Available at: 10.1016/j.nbt.2010.01.084.
Pekova, S. et al. (2009) “Molecular variability of FLT3/ITD mutants and their impact on the differentiation program of 32D cells: Implications for the biological properties of AML blasts”, Leukemia Research, 33(10), pp. 1409–1416. Available at: 10.1016/j.leukres.2009.01.004.
Petrak, J. et al. (2008) “Déjà vu in proteomics. A hit parade of repeatedly identified differentially expressed proteins”, Proteomics, 8(9), pp. 1744–1749. Available at: 10.1002/pmic.200700919.
Homolka, D. et al. (2007) “Chromosomal rearrangement interferes with meiotic X chromosome inactivation”, Genome Research, 17(10), pp. 1431–1437. Available at: 10.1101/gr.6520107.