Selected Publications
Please find below a selection of publications from the Department of Biomedicine.
If you are looking for publications of a specific group please refer to the corresponding research group.
August 2021 - September 2024
| Circovirus hepatitis in an immunocompromised patient, Switzerland. Hamelin B, Pérot P, Pichler I, Haslbauer JD, Hardy D, Hing D, Louliz S, Regnault B, Pieters A, Heijnen I, Berkemeier C, Mancuso M, Kufner V, Willi N, Jamet A, Dheilly N, Eloit M, Recher M, Huber M, Mertz KD. Emerg Infect Dis. 2024 Oct. doi: 10.3201/eid3010.240678. Online ahead of print. https://wwwnc.cdc.gov/eid/article/30/10/24-0678_article |
| The second international consensus guidelines on the management of BK polyomavirus in kidney transplantation. Kotton CN, Kamar N, Wojciechowski D, Eder M, Hopfer H, Randhawa P, Sester M, Comoli P, Tedesco Silva H, Knoll G, Brennan DC, Trofe-Clark J, Pape L, Axelrod D, Kiberd B, Wong G, Hirsch HH. Transplantation. 2024 Sept 108(9):p 1834-1866 doi: 10.1097/TP.0000000000004976. https://journals.lww.com/transplantjournal/fulltext/2024/09000/the_second_international_consensus_guidelines_on.7.aspx |
| T cell receptor architecture and clonal tiding provide insight into the transformation trajectory of peripheral T cell lymphomas. Willscher E, Schultheiß C, Paschold L, Schümann FL, Schmidt-Barbo P, Thiele B, Bauer M, Wickenhauser C, Weber T, Binder M. Haematologica. 2024 Aug 29. doi: 10.3324/haematol.2024.285395. Online ahead of print. https://haematologica.org/article/view/haematol.2024.285395 |
| Stem cell memory EBV-specific T cells control EBV tumor growth and persist in vivo. Palianina D, Mietz J, Stühler C, Arnold B, Bantug G, Münz C, Chijioke O, Khanna N. Sci Adv. 2024 Aug 23;10(34):eado2048. doi: 10.1126/sciadv.ado2048. Epub 2024 Aug 23. https://www.science.org/doi/full/10.1126/sciadv.ado2048 |
| Semaphorin 3A promotes the long-term persistence of human SVF-derived microvascular networks in engineered grafts. Schwager JM, Di Maggio N, Grosso A, Rasadurai A, Minder N, Hubbell JA, Kappos EA, Schaefer DJ, Briquez PS, Banfi A and Burger MG Front. Bioeng. Biotechnol. 12: 1396450 (2024)doi: 10.3389/fbioe.2024.1396450. https://www.frontiersin.org/journals/bioengineering-and-biotechnology/articles/10.3389/fbioe.2024.1396450/full |
| A20 haploinsufficiency disturbs immune homeostasis and drives the transformation of lymphocytes with permissive antigen receptors. Schultheiß C, Paschold L, Mohebiany AN, Escher M, Kattimani YM, Müller M, Schmidt-Barbo P, Mensa-Vilaró A, Aróstegui JI, Boursier G, de Moreuil C, Hautala T, Willscher E, Jonas H, Chinchuluun N, Grosser B, Märkl B, Klapper W, Oommen PT, Gössling K, Hoffmann K, Tiegs G, Czernilofsky F, Dietrich S, Freeman A, Schwartz DM, Waisman A, Aksentijevich I, Binder M. Sci Adv. 2024 Aug 23;10(34):eadl3975. doi: 10.1126/sciadv.adl3975. Epub 2024 Aug 21. https://www.science.org/doi/full/10.1126/sciadv.adl3975?rfr_dat=cr_pub++0pubmed&url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org |
| Polygenic susceptibility for multiple sclerosis is associated with working memory in low-performing young adults. Petrovska J, Coynel D, Freytag V, de Quervain D J-F, Papassotiropoulos A. J Neurol Sci. 2024 Jul 15:463:123138. doi: 10.1016/j.jns.2024.123138. Online ahead of print. https://www.sciencedirect.com/science/article/pii/S0022510X24002739?via%3Dihub |
| Engineered autologous nasal cartilage for repair of nasal septal perforations - a case series. Kaiser B, Miot S, Wixmerten A, Pullig O, Eyrich M, Fulco I, Vavrina J, Schaefer DJ, Martin I, Barbero A, Haug M. Int J Surg. 2024 Aug 5. doi: 10.1097/JS9.0000000000001843. Online ahead of print. https://journals.lww.com/international-journal-of-surgery/abstract/9900/engineered_autologous_nasal_cartilage_for_repair.1870.aspx |
| B cells expressing mutated IGHV1-69-encoded antigen receptors related to virus neutralization show lymphoma-like transcriptomes in patients with chronic HCV infection. Schultheiß C, Willscher E, Paschold L, Ackermann C, Escher M, Scholz R, Knapp M, Lützkendorf J, Müller LP, Schulze Zur Wiesch J, Binder M. Hepatol Commun. 2024 Jul 31;8(8):e0503. doi: 10.1097/HC9.0000000000000503. eCollection 2024 Aug 1. https://journals.lww.com/hepcomm/fulltext/2024/08010/b_cells_expressing_mutated_ighv1_69_encoded.19.aspx |
| Factor H-related protein 1 in systemic lupus erythematosus. Kleer JS, Klehr J, Dubler D, Infanti L, Chizzolini C, Huynh-Do U, Ribi C, Trendelenburg M. Front Immunol. 2024 Jul 29:15:1447991. doi: 10.3389/fimmu.2024.1447991. eCollection 2024. https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2024.1447991/full |
| Monoallelic de novo AJAP1 loss-of-function variants disrupt trans-synaptic control of neurotransmitter release. Früh S, Boudkkazi S, Koppensteiner P, Sereikaite V, Chen L-Y, Fernandez- Fernandez D, Rem P D, Ulrich D, Schwenk J, Chen Z, Le Monnier E, Fritzius T, Innocenti S M, Besseyrias V, Trovò L, Stawarski M, Argilli E, Sherr E H, van Bon B, Kamsteeg E-J, Iascone M, Pilotta A, Cutrì M R, Azamian M S, Hernández-García H, Lalani S R, Rosenfeld J A, Zhao X, Vogel T P, Ona H, Scott A D, Scheiffele P, Strømgaard K, Tafti M, Gassmann M, Fakler B,Shigemoto R, Bettler B. Sci Adv. 2024 Jul 12;10(28):eadk5462. doi: 10.1126/sciadv.adk5462. Epub 2024 Jul 10. https://www.science.org/doi/10.1126/sciadv.adk5462 |
| Detection of disease-specific signatures in B cell repertoires of lymphomas using machine learning. Schmidt-Barbo P, Kalweit G, Naouar M, Paschold L, Willscher E, Schultheiß C, Märkl B, Dirnhofer S, Tzankov A, Binder M, Kalweit M. PLoS Comput Biol. 2024 Jul 2;20(7):e1011570. doi: 10.1371/journal.pcbi.1011570. eCollection 2024 Jul. https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1011570 |
| Engineered human osteoarthritic cartilage organoids. Dönges L, Damle A, Mainardi A, Bock T, Schönenberger M, Martin I, Barbero A. Biomaterials. 2024 Jul:308:122549. doi: 10.1016/j.biomaterials.2024.122549. Epub 2024 Mar 22. https://www.sciencedirect.com/science/article/pii/S0142961224000838?via%3Dihub |
| Trifluridine/Tipiracil Based Chemoradiation in locally Advanced Rectal Cancer: The Phase I/II TARC Trial. Thiele B, Stein A, Schultheiß C, Paschold L, Jonas H, Goekkurt E, Rüssel J, Schuch G, Wierecky J, Sinn M, Tintelnot J, Petersen C, Rothkamm K, Vettorazzi E, Binder M. Clin Colorectal Cancer. 2024 Jun 22:S1533-0028(24)00059-8. doi: 10.1016/j.clcc.2024.06.003. Online ahead of print. https://www.sciencedirect.com/science/article/pii/S1533002824000598?via%3Dihub |
| Engineered phalangeal grafts for children with symbrachydactyly: A proof of concept. Schaller R, Moya A, Zhang G, Chaaban M, Paillaud R, Bartoszek EM, Schaefer DJ, Martin I, Kaempfen A, Scherberich A. J Tissue Eng. 2024 Jun 12:15:20417314241257352. doi: 10.1177/20417314241257352. eCollection 2024 Jan-Dec. https://journals.sagepub.com/doi/10.1177/20417314241257352?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed |
| TBX3 is essential for establishment of the posterior boundary of anterior genes and upregulation of posterior genes together with HAND2 during the onset of limb bud development. Soussi G, Girdziusaite A, Jhanwar S, Palacio V, Notaro M, Sheth R, Zeller R, Zuniga A. Development. 2024 Jun 1;151(11):dev202722. doi: 10.1242/dev.202722. Epub 2024 Jun 3. https://journals.biologists.com/dev/article/151/11/dev202722/352270/TBX3-is-essential-for-establishment-of-the |
| A metabolic dependency of EBV can be targeted to hinder B cell transformation. Müller-Durovic B, Jäger J, Christine E, Schuhmachers P, Altermatt S, Schlup Y, Duthaler U, Makowiec C, Unterstab G, Roffeis S, Xhafa E, Assmann N, Trulsson F, Steiner R, Edwards-Hicks J, West J, Turner L, Develioglu L, Ivanek R, Azzi T, Dehio P, Berger C, Kuzmin D, Saboz S, Mautner J, Löliger J, Geigges M, Palianina D, Khanna N, Dirnhofer S, Münz C, Bantug GR, Hess C. IF 56.9 Science. 2024 May 23:eadk4898. doi: 10.1126/science.adk4898. IF 56.9 https://www.science.org/doi/10.1126/science.adk4898 |
| Selective haematological cancer eradication with preserved haematopoiesis. Garaudé S, Marone R, Lepore R, Devaux A, Beerlage A, Seyres D, Dell’Aglio A, Juskevicius D, Zuin J, Burgold T, Wang S, Katta V, Manquen G, Li Y, Larrue C, Camus A, Durzynska I, Simonetta LCF, Urlinger S, Jeker LT. Science. 2024 May 23:eadk4898. doi: 10.1126/science.adk4898. IF 64.8 https://www.nature.com/articles/s41586-024-07456-3 |
| CaMKIIβ deregulation contributes to neuromuscular junction destabilization in Myotonic Dystrophy type I. Falcetta D, Quirim S, Cocchiararo I, Chabry F, Théodore M, Stiefvater A, Lin S, Tintignac L, Ivanek R, Kinter J, Rüegg MA, Sinnreich M, Castets P. Skelet Muscle. 2024 May 21;14(1):11. doi: 10.1186/s13395-024-00345-3. https://skeletalmusclejournal.biomedcentral.com/articles/10.1186/s13395-024-00345-3 |
| Nucleobase adducts bind MR1 and stimulate MR1-restricted T cells. Vacchini A, Chancellor A, Yang Q, Colombo R, Spagnuolo J, Berloffa G, Joss D, Øyås O, Lecchi C, De Simone G, Beshirova A, Nosi V, Loureiro JP, Morabito A, De Gregorio C, Pfeffer M, Schaefer V, Prota G, Zippelius A, Stelling J, Häussinger D, Brunelli L, Villalba P, Lepore M, Davoli E, Balbo S, Mori L, De Libero G. Sci Immunol. 2024 May 10;9(95):eadn0126. doi: 10.1126/sciimmunol.adn0126. IF 24.8 https://www.science.org/doi/10.1126/sciimmunol.adn0126 |
| Synaptotagmin-11 facilitates assembly of a presynaptic signaling complex in post-Golgi cargo vesicles. Trovò L, Kouvaros S, Schwenk J, Fernandez-Fernandez D, Fritzius T, Rem P D, Früh S, Gassmann M, Fakler B, Bischofberger J, Bettler B. EMBO Rep. 2024 Jun;25(6):2610-2634. doi: 10.1038/s44319-024-00147-0. Epub 2024 May 2. https://www.embopress.org/doi/full/10.1038/s44319-024-00147-0 |
| Inhibition of the transmembrane transporter ABCB1 overcomes resistance to doxorubicin in patient-derived organoid models of HCC. Blukacz L, Nuciforo S, Fucile G, Trulsson F, Duthaler U, Wieland S T, Heim M H. Hepatol Commun. 2024 May 2;8(5):e0437. doi: 10.1097/HC9.0000000000000437. eCollection 2024 May 1. https://journals.lww.com/hepcomm/fulltext/2024/05010/inhibition_of_the_transmembrane_transporter_abcb1.11.aspx |
| Clonal heterogeneity leads to secondary resistance in a melanoma patient after adoptive cell therapy with tumor-infiltrating lymphocytes. König D., Sandholzer M., Uzun S., Zingg A., Ritschard R., Thut H., Glatz K., Kappos E.A., Schaefer D.J., Kettelhack C., Passweg J.R., Holbro A., Baur K., Medinger M., Buser A., Lardinois D., Jeker L.T., Khanna N., Stenner F., Kasenda B., Homicsko K., Matter M., Rodrigues Mantuano N., Zippelius A., Läubli H. Cancer Immunol Res. 2024 Apr 17. doi: 10.1158/2326-6066.CIR-23-0757. Online ahead of print. IF 10.1 https://aacrjournals.org/cancerimmunolres/article/doi/10.1158/2326-6066.CIR-23-0757/743089/Melanoma-clonal-heterogeneity-leads-to-secondary |
| Neurofilaments as biomarkers in neurological disorders — towards clinical application. Khalil M ,Teunissen Ch E, Lehmann S, Otto M, Piehl F, Ziemssen T, Bittner St, Sormani M P, Gattringer T, Abu-Rumeileh S, Thebault S, Abdelhak A, Green A, Benkert P, Kappos L, Comabella M, Tumani H, Freedman M S, Petzold A, Blennow K, Zetterberg H, Leppert D & Kuhle J. Nat Rev Neurol. 2024 Apr 12. doi: 10.1038/s41582-024-00955-x. IF 38.1 https://www.nature.com/articles/s41582-024-00955-x |
| Role of GLR-1 in Age-Dependent Short-Term Memory Decline. Gharat V, Peter F, de Quervain D , Papassotiropoulos A and Stetak A. eNeuro. 2024 Apr 9;11(4):ENEURO.0420-23.2024. doi: 10.1523/ENEURO.0420-23.2024. Print 2024 Apr. IF 3.4 https://www.eneuro.org/content/11/4/ENEURO.0420-23.2024 |
| Preassembly of specific Gβγ subunits at GABAB receptors through auxiliary KCTD proteins accelerates channel gating. Fritzius T, Tureček R, Fernandez-Fernandez D, Isogai S, Rem P D, Kralikova M, Gassmann M, Bettler B. Biochem Pharmacol. 2024 Mar 28:116176. doi: 10.1016/j.bcp.2024.116176. Online ahead of print. https://www.sciencedirect.com/science/article/pii/S000629522400159X?via%3Dihub |
| Engineered human osteoarthritic cartilage organoids. Doenges L, Damle A, Mainardi A, Bock T, Schoenenberger M, Martin I, Barbero A. Biomaterials. 2024 Jul:308:122549. doi: 10.1016/j.biomaterials.2024.122549. Epub 2024 Mar 22. IF 14 https://www.sciencedirect.com/science/article/pii/S0142961224000838?via%3Dihub |
| Structural implications of BK polyomavirus sequence variations in the major viral capsid protein Vp1 and large T-antigen: a computational study. Durairaj J, Follonier OM, Leuzinger K, Alexander LT, Wilhelm M, Pereira J, Hillenbrand CA, Weissbach FH, Schwede T, Hirsch HH. mSphere. 2024 Apr 23;9(4):e0079923. doi: 10.1128/msphere.00799-23. Epub 2024 Mar 19. IF 4.8 https://journals.asm.org/doi/10.1128/msphere.00799-23 |
| T helper cells exhibit a dynamic and reversible 3'-UTR landscape. Seyres D, Gorka O, Schmidt R, Marone R, Zavolan M, Jeker LT. RNA. 2024 Mar 18;30(4):418-434. doi: 10.1261/rna.079897.123. IF 4.5 https://rnajournal.cshlp.org/content/30/4/418 |
| Loss of Dnmt3a increased self-renewal and resistance to pegIFNα in JAK2-V617F-positive myeloproliferative neoplasms. Usart M, Stetka J, Luque Paz D, Hansen N, Kimmerlin Q, Almeida Fonseca T, Lock M, Kubovcakova L, Karjalainen R, Hao-Shen H, Börsch A, El Taher A, Schulz J, Leroux JC, Dirnhofer S, Skoda RC. Blood. 2024 Mar 17:blood.2023020270. doi: 10.1182/blood.2023020270. Online ahead of print. PMID: 38493481 IF 20.3 https://ashpublications.org/blood/article/doi/10.1182/blood.2023020270/515323/Loss-of-Dnmt3a-increased-self-renewal-and |
| Management of Patients with Hypersensitivity to Platinum Salts and Taxane in Gynecological Cancers: A Cross-Sectional Study by the European Network of Young Gynaecologic Oncologists (ENYGO). Zwimpfer TA, Bilir E, Gasimli K, Cokan A, Bizzarri N, Razumova Z, Kacperczyk-Bartnik J, Nikolova T, Pletnev A, Kahramanoglu I, Shushkevich A, Strojna A, Theofanakis C, Cicakova T, Vetter M, Montavon C, Morgan G, Heinzelmann-Schwarz V. Cancers (Basel). 2024 Mar 14;16(6):1155. doi: 10.3390/cancers16061155. https://www.mdpi.com/2072-6694/16/6/1155 |
| Engagement of sialylated glycans with Siglec receptors on suppressive myeloid cells inhibits anticancer immunity via CCL2. Wieboldt R., Sandholzer M., Carlini E., Lin C.-W., Börsch A., Zingg A., Lardinois D., Herzig P., Don L., Zippelius A., Läubli H. , Rodrigues Mantuano N. Cell Mol Immunol, 2024 Mar 6. doi: 10.1038/s41423-024-01142-0. Online ahead of print. IF 24.1 https://www.nature.com/articles/s41423-024-01142-0 |
| B cell depletion with anti-CD20 promotes neuroprotection in a BAFF-dependent manner in mice and humans. Wang AA, Luessi F, Neziraj T, Pössnecker E, Zuo M, Engel S, Hanuscheck N, Florescu A, Bugbee E, Ma XI, Rana F, Lee D, Ward LA, Kuhle J, Himbert J, Schraad M, van Puijenbroek E, Klein C, Urich E, Ramaglia V, Pröbstel AK, Zipp F, Gommerman JL. Sci Transl Med. 2024 Mar 6;16(737):eadi0295. doi: 10.1126/scitranslmed.adi0295. Epub 2024 Mar 6. IF 17.1 https://www.science.org/doi/10.1126/scitranslmed.adi0295 |
| Central tolerance shapes the neutralizing B cell repertoire against a persisting virus in its natural host. Florova M, Abreu-Mota T, Paesen GC, Beetschen AN, Cornille K, Marx AF , Narr K , Sahin M, Dimitrova M, Swarnalekha N, Beil-Wagner J, Savic N, Pelczar P, Buch T, King CG, A Bowden T, Pinschewer DD. Proc Natl Acad Sci U S A.2024 Mar 12;121(11):e2318657121. doi: 10.1073/pnas.2318657121. Epub 2024 Mar 6. IF 11.1 https://www.pnas.org/doi/10.1073/pnas.2318657121 |
| A novel, patient-derived RyR1 mutation impairs muscle function and calcium homeostasis in mice. Benucci S, Ruiz A, Franchini M, Ruggiero L, Zoppi D, Sitsapesan R, Lindsay Ch, Pelczar P, Pietrangelo L, Protasi F, Treves S, Zorzato F. J Gen Physiol. 2024 Apr 1;156(4):e202313486. doi: 10.1085/jgp.202313486. Epub 2024 Mar 4. IF 3.8 https://rupress.org/jgp/article-abstract/156/4/e202313486/276594/A-novel-patient-derived-RyR1-mutation-impairs?redirectedFrom=fulltext |
| Cell-binding IgM in CSF is distinctive of multiple sclerosis and targets the iron transporter SCARA5. Callegari I, Oechtering J, Schneider M, Perriot S, Mathias A, Voortman MM, Cagol A, Lanner U, Diebold M, Holdermann S, Kreiner V, Becher B, Granziera C, Junker A, Du Pasquier R, Khalil M, Kuhle J, Kappos L, Sanderson NSR, Derfuss T. Brain. 2024 Mar 1;147(3):839-848. doi: 10.1093/brain/awad424. IF 14.5 https://academic.oup.com/brain/article/147/3/839/7484616?login=true |
| IL-1β promotes MPN disease initiation by favoring early clonal expansion of JAK2-mutant hematopoietic stem cells. Rai S, Zhang Y, Grockowiak E, Kimmerlin Q, Hansen N, Stoll CB, Usart M, Luque Paz D, Hao-Shen H, Zhu Y, Roux J, Bader MS, Dirnhofer S, Farady CJ, Schroeder T, Méndez-Ferrer S, Skoda RC. Blood Adv. 2024 Mar 12;8(5):1234-1249. doi: 10.1182/bloodadvances.2023011338. IF 7.6 https://ashpublications.org/bloodadvances/article/8/5/1234/507118/IL-1-promotes-MPN-disease-initiation-by-favoring |
| Tolerability and Efficacy of the Cancer Vaccine UV1 in Patients With Recurrent or Metastatic PD-L1 positive Head and Neck Squamous Cell Carcinoma Planned for First-line Treatment with Pembrolizumab -the Randomized Phase 2 FOCUS Trial. Brandt A, Schultheiß C, Klinghammer K, Schafhausen P, Busch CJ, Blaurock M, Hinke A, Tometten M, Dietz A, Müller-Richter U, Hahn D, Alt J, Stein A, Binder M. Front Oncol. 2024 Feb 7:14:1283266. doi: 10.3389/fonc.2024.1283266. eCollection 2024. https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2024.1283266/full |
| SARS-CoV-2 vaccination may mitigate dysregulation of IL-1 family cytokines and gastrointestinal symptoms of the post-COVID-19 condition. Fischer C, Willscher E, Paschold L, Gottschick C, Klee B, Diexer S, Bosurgi L, Dutzmann J, Sedding D, Frese T, Girndt M, Hoell JI, Gekle M, Addo MM, Schulze zur Wiesch J, Mikolajczyk R, Binder M, Schultheiß C. NPJ Vaccines. 2024 Feb 5;9(1):23. doi: 10.1038/s41541-024-00815-1. https://www.nature.com/articles/s41541-024-00815-1 |
| Mutation-specific CAR T cells as precision cell therapy for IGLV3-21R110 expressing high-risk chronic lymphocytic leukemia. Märkl F, Schultheiß C, Ali M, Chen SS, Zintchenko M, Egli L, Mietz J, Chijioke O, Paschold L, Spajic S, Holtermann A, Dörr J, Stock S, Piseddu I, Anz D, Dühren-von Minden M, Zhang T, Nerreter T, Hudecek M, Minguet S, Chiorazzi N, Kobold S, Binder M. Nat Commun. 2024 Feb 2;15(1):993. doi: 10.1038/s41467-024-45378-w. https://www.nature.com/articles/s41467-024-45378-w |
| Development of Resistance to Type II JAK2 Inhibitors in MPN Depends on AXL Kinase and Is Targetable. Codilupi T, Szybinski J, Arunasalam S, Jungius S, Dunbar AC, Stivala S, Brkic S, Albrecht C, Vokalova L, Yang JL, Buczak K, Ghosh N, Passweg JR, Rovo A, Angelillo-Scherrer A, Pankov D, Dirnhofer S, Levine RL, Koche R, Meyer SC. Clin Cancer Res. 2024 Feb 1;30(3):586-599. doi: 10.1158/1078-0432.CCR-23-0163. https://aacrjournals.org/clincancerres/article/30/3/586/733543/Development-of-Resistance-to-Type-II-JAK2 |
| SARS-CoV-2-associated T-cell infiltration in the central nervous system. Mohme M, Schultheiß C, Piffko A, Fitzek A, Paschold L, Thiele B, Püschel K, Glatzel M, Westphal M, Lamszus K, Matschke J, Binder M. Clin Transl Immunology. 2024 Jan 31;13(2):e1487. doi: 10.1002/cti2.1487. eCollection 2024. https://onlinelibrary.wiley.com/doi/10.1002/cti2.1487 |
| The glutaminase inhibitor CB-839 targets metabolic dependencies of JAK2-mutant hematopoiesis in MPN. Usart M, Hansen N, Stetka J, Almeida Fonseca T, Guy A, Kimmerlin Q, Rai S, Hao-Shen H, Roux J, Dirnhofer S, Skoda RC. Blood Adv. 2024 Jan 31:bloodadvances.2023010950. doi: 10.1182/bloodadvances.2023010950. Online ahead of print. PMID: 38295283 https://ashpublications.org/bloodadvances/article/8/9/2312/514787/The-glutaminase-inhibitor-CB-839-targets-metabolic |
| Single-cell characterization of human GBM reveals regional differences in tumor-infiltrating leukocyte activation. Schmassmann P, Roux J, Dettling S, Hogan S, Shekarian T, Martins TA, Ritz MF, Herter S, Bacac M, Hutter G. Elife.2023 Dec 21:12:RP92678. doi: 10.7554/eLife.92678. https://elifesciences.org/articles/92678 |
Development of resistance to type II JAK2 inhibitors in MPN depends on AXL kinase and is targetable. Codilupi T, Szibinki J, Arunasalam S, Jungius S, Dunbar AC, Stivala S, Brkic S, Albrecht C, Vokalova L, Yang JL, Buczak K, Ghosh N, Passweg JR, Rovo A, Angelillo-Scherrer A, Pankov D, Dirnhofer S, Levine RL, Koche R, Meyer SC. Clin Cancer Res. 2024 Feb 1;30(3):586-599. doi: 10.1158/1078-0432.CCR-23-0163. https://aacrjournals.org/clincancerres/article/30/3/586/733543/Development-of-Resistance-to-Type-II-JAK2 |
| Sequential maturation of stimulus-specific adaptation in the mouse lemniscal auditory system. Valerio P, Rechenmann J, Joshi S, De Franceschi G, Barkat Rinaldi T. Sci Adv. 2024 Jan 5;10(1):eadi7624. doi: 10.1126/sciadv.adi7624. Epub 2024 Jan 3. https://pubmed.ncbi.nlm.nih.gov/38170771/ |
| Effects of calibrated blue–yellow changes in light on the human circadian clock. Blume Ch, Cajochen Ch, Schöllhorn I, Slawik H C, Spitschan M. Nat Hum Behav. 2023 Dec 22. doi: 10.1038/s41562-023-01791-7. Online ahead of print. https://www.nature.com/articles/s41562-023-01791-7#author-information |
| The Flt3-inhibitor quizartinib augments apoptosis and promotes maladaptive remodeling after myocardial infarction in mice. Belik DM, Bernasconi R, Xu L, Verde GD, Lorenz V, Grüterich V, Balzarolo M, Mochizuki M, Pfister O, Kuster GM. Apoptosis (2023). doi.org/10.1007/s10495-023-01911-8 https://link.springer.com/article/10.1007/s10495-023-01911-8 |
| Harnessing human adipose-derived stromal cell chondrogenesis in vitro for enhanced endochondral ossification. Chaaban M, Moya A, García-García A, Paillaud R, Schaller R, Klein T, Power L, Buczak K, Schmidt A, Kappos E, Ismail T, Schaefer DJ, Martin I, Scherberich A. Biomaterials. 2023 Dec:303:122387. doi: 10.1016/j.biomaterials.2023.122387. Epub 2023 Nov 6. https://www.sciencedirect.com/science/article/pii/S0142961223003952 |
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| A method for polyclonal antigen-specific T cell-targeted genome editing (TarGET) for adoptive cell transfer applications. Palianina D, Di Roberto RB, Castellanos-Rueda R, Schlatter F, Reddy ST, Khanna N. Mol Ther Methods Clin Dev. 2023 Jun 19:30:147-160. doi: 10.1016/j.omtm.2023.06.007. eCollection 2023 Sep 14. https://www.sciencedirect.com/science/article/pii/S2329050123000979?via%3Dihub |
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| An Animal Model for Chronic Meningeal Inflammation and Inflammatory Demyelination of the Cerebral Cortex. Enz LS, Winkler A, Wrzos C, Dasen B, Nessler S, Stadelmann C, Schaeren-Wiemers N. Int J Mol Sci. 2023 Sep 9;24(18):13893. doi: 10.3390/ijms241813893. https://www.mdpi.com/1422-0067/24/18/13893 |
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| Exogenous humanin and MOTS-c function as protective agents against gentamicin-induced hair cell damage. Waldmann D, Lu Y, Cortada M, Bodmer D, Huaman SL. Biochem Biophys Res Commun. 2023 Oct 20:678:115-121. doi: 10.1016/j.bbrc.2023.08.033. Epub 2023 Aug 17. https://www.sciencedirect.com/science/article/pii/S0006291X23009798?via%3Dihub |
| Characterization of engraftment dynamics in myelofibrosis after allogeneic hematopoietic cell transplantation including novel conditioning schemes. Jungius S, Adam FC, Grosheintz K, Medinger M, Buser A, Passweg JR, Halter JP, Meyer SC. Front Oncol. 2023 Aug 10:13:1205387. doi: 10.3389/fonc.2023.1205387. eCollection 2023. https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2023.1205387/full |
| Urine CXCL10 to Assess BK Polyomavirus Replication After Kidney Transplantation. Haller J, Diebold M, Leuzinger K, Wehmeier C, Handschin J, Amico P, Hirt-Minkowski P, Steiger J, Dickenmann M, Hirsch HH, Schaub S. Transplantation. 2023 Dec 1;107(12):2568-2574. doi: 10.1097/TP.0000000000004712. Epub 2023 Jul 6. https://journals.lww.com/transplantjournal/fulltext/2023/12000/urine_cxcl10_to_assess_bk_polyomavirus_replication.27.aspx |
Regulator of G-protein signaling 1 critically supports CD8+TRM cell-mediated intestinal immunity. von Werdt D, Gungor B, Barreto de Albuquerque J, Gruber T, Zysset D, Kwong Chung CKC, Corrêa-Ferreira A, Berchtold R, Page N, Schenk M, Kehrl JH, Merkler D, Imhof BA, Stein JV, Abe J, Turchinovich G, Finke D, Hayday AC, Corazza N, Mueller C. Front Immunol. 2023 Apr 20:14:1085895. doi: 10.3389/fimmu.2023.1085895. eCollection 2023. https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2023.1085895/full |
| Targeting the Siglec–sialic acid axis promotes antitumor immune responses in preclinical models of glioblastoma. P Schmassmann, J Roux, A Buck, N Tatari, S Hogan, J Wang, N R Mantuano, R Wieboldt, S Lee, B Snijder, D Kaymak, T A Martins, M F Ritz, T Shekarian, M Mcdaid, M Weller, T Weiss, H Läubli, G Hutter. DOI: 10.1126/scitranslmed.adf5302. https://www.science.org/doi/10.1126/scitranslmed.adf5302 |
| Human epidermis organotypic cultures, a reproducible system recapitulating the epidermis in vitro. Experimental Dermatology. Rishika Agarwal, Tanja Dittmar, Hans-Dietmar Beer, Michael Kunz, Simon Müller, Elisabeth A. Kappos, Emmanuel Contassot, Alexander A. Navarini (2023). 2023;00:1-13. doi:10.1111/exd.14823 https://onlinelibrary.wiley.com/doi/full/10.1111/exd.14823 |
| Iron is a modifier of the phenotypes of JAK2-mutant myeloproliferative neoplasms. Stetka J, Usart M,Kubovcakova L,Rai S, Nageswara Rao T, Sutter J, Hao-Shen H,Dirnhofer S, Geier F, Bader M, Passweg J, Manolova V, Dürrenberger F, Ahmed N, Schroeder T, Ganz T, Nemeth E, Silvestri L, Nai A, Camaschella C and Skoda R. Blood. 2023 Apr 27;141(17):2127-2140. doi: 10.1182/blood.2022017976. 27.04.23 https://pubmed.ncbi.nlm.nih.gov/36758212/ |
| N-acetylcysteine overcomes NF1 loss-driven resistance to PI3Kα inhibition in breast cancer. Auf der Maur P, Trefny MP, Baumann Z, Vulin M, Correia AL, Diepenbruck M, Kramer N, Volkmann K, Preca BT, Ramos P, Leroy C, Eichlisberger T, Buczak K, Zilli F, Okamoto R, Rad R, Jensen MR, Fritsch C, Zippelius A, Stadler MB, Bentires-Alj M. Cell Rep Med. 2023 Apr 18;4(4):101002. doi: 10.1016/j.xcrm.2023.101002. Epub 2023 Apr 11. PMID: 37044095 18.04.23 https://pubmed.ncbi.nlm.nih.gov/37044095/ |
| DNA methylation landscapes of prostate cancer brain metastasis are shaped by early driver genetic alterations. Gallon J, Rodriguez-Calero A, Benjak A, Akhoundova D, Maletti S, Amstutz U, Hewer E, Genitsch V, Fleischmann A, Rushing EJ, Grobholz R, Fischer I, Jochum W, Cathomas G, Osunkoya AO, Bubendorf L, Moch H, Thalmann G, Feng FY, Gillessen S, Ng CKY, Rubin MA, Piscuoglio S. Cancer Res. 2023 Apr 14;83(8):1203-1213. doi: 10.1158/0008-5472.CAN-22-2236. 14.04.23 https://pubmed.ncbi.nlm.nih.gov/36749655/ |
| Pharmacokinetics and Pharmacodynamics of Oral Psilocybin Administration in Healthy Participants. Holze F, Becker AM, Kolaczynska KE, Duthaler U and Liechti ME. Clin Pharmacol Ther. 2023 Apr;113(4):822-831. doi: 10.1002/cpt.2821. Epub 2022 Dec 31. 01.04.23 https://pubmed.ncbi.nlm.nih.gov/36507738/ |
| AXL expression on homeostatic resident liver macrophages is reduced in cirrhosis following GAS6 production by hepatic stellate cells. Holze F, Becker AM, Kolaczynska KE, Duthaler U and Liechti ME. Cell Mol Gastroenterol Hepatol. 2023 Mar 31;S2352-345X(23)00047-4. doi: 10.1016/j.jcmgh.2023. 03.007. Online ahead of print. 31.03.23 https://www.sciencedirect.com/science/article/pii/S2352345X23000474?via%3Dihub |
| Autoimmunity and immunodeficiency associated with monoallelic LIG4 mutations via haploinsufficiency. Jauch A, Bignucolo O, Seki S, Ghraichy M, Delmonte O, von Niederhäusern V, Higgins R, Ghosh A, Nishizawa M, Tanaka M, Baldrich A, Köppen J, Hirsiger J, Hupfer R, Ehl S, Rensing-Ehl A, Hopfer H, Savic Prince S, Daley S, Marquardsen F, Meyer B, Tamm M, Daikeler T, Diesch T, Kühne T, Helbling A, Berkemeier C, Heijnen I, Navarini A, Trück J, de Villartay J.-P., Oxenius A, Berger Ch, Hess Ch, D Notarangelo L, Yamamoto H, Recher M. Allergy Clin Immunol. 2023 Mar 31;S0091-6749(23)00422-0. doi: 10.1016/j.jaci.2023.03.022. Online ahead of print. 31.03.23 https://pubmed.ncbi.nlm.nih.gov/37004747/ |
| VEGF dose controls the coupling of angiogenesis and osteogenesis in engineered bone. Grosso A, Lunger A, Burger MG, Briquez PS, Mai F, Hubbell JA, Schaefer DJ, Banfi A, Di Maggio N. NPJ Regen Med. 2023 Mar 13;8(1):15. doi: 10.1038/s41536-023-00288-1. 13.03.23 https://pubmed.ncbi.nlm.nih.gov/36914692/ |
| Lung versus gut exposure to air pollution particles differentially affect metabolic health in mice. Bosch AJT, Rohm TV, AlAsfoor S, Low AJY, Keller L, Baumann Z, Parayil N, Stawiski M, Rachid L, Dervos T, Mitrovic S, Meier DT, Cavelti-Weder C. Part Fibre Toxicol. 2023 Mar 9;20(1):7. doi: 10.1186/s12989-023-00518-w. 09.03.23 https://pubmed.ncbi.nlm.nih.gov/36895000/ |
| Good Manufacturing Practice-compliant change of raw material in the manufacturing process of a clinically used advanced therapy medicinal product-a comparability study. Wixmerten A, Miot S, Bittorf P, Wolf F, Feliciano S, Hackenberg S, Häusner S, Krenger W, Haug M, Martin I, Pullig O, Barbero A. Cytotherapy. 2023 May;25(5):548-558. doi: 10.1016/j.jcyt.2023.01.003. Epub 2023 Mar 7. PMID: 36894437. 07.03.23 https://pubmed.ncbi.nlm.nih.gov/36894437/ |
| Quantitative proteomic analysis of skeletal muscles from wild-type and transgenic mice carrying recessive Ryr1 mutations linked to congenital myopathies. Eckhardt J, Ruiz A, Koenig S, Frieden M, Meier H, Schmidt A, Treves S, Zorzato F. Elife. 2023 Mar 2;12:e83618. doi: 10.7554/eLife.83618. 02.03.23 https://pubmed.ncbi.nlm.nih.gov/36862731/ |
| T-cadherin is a novel regulator of pericyte function during angiogenesis. Dasen B, Pigeot S, Born GM, Verrier S, Rivero O, Dittrich PS, Martin I, Filippova M. Am J Physiol Cell Physiol, Feb 20, Online, ahead of print (2023). doi: 10.1152/ajpcell.00326.2022. PMID: 36802732. 20.02.23 https://pubmed.ncbi.nlm.nih.gov/36802732/ |
| Doublecortin and Glypican-2 concentrations in the cerebrospinal fluid from infants are developmentally downregulated. Brégère C, Fisch U, Halbeisen FS, Schneider C, Dittmar T, Stricker S, Aghlmandi S, Guzman R. PLoS One. 2023 Feb 17;18(2):e0279343. doi: 10.1371/journal.pone.0279343. eCollection 2023. 17.02.23 https://pubmed.ncbi.nlm.nih.gov/36800341/ |
| Dynamics of antibody titers to SARS-CoV-2 and clinical outcomes after sotrovimab pre-exposure prophylaxis early after allogeneic hematopoietic stem cell transplantation. Capoferri G, Walti CS, Urwyler P, Ragozzino S, Passweg JR, Halter J, Battegay M, Baettig V, Weisser M, Arnold B, Morin B, Guetlin Y, Torres DA, Barut GT, Thiel V, Egli A, Drexler B, Khanna N. Bone Marrow Transplant. 2023 Feb 16;1-3. doi: 10.1038/s41409-023-01936-2. Online ahead of print. 16.02.23 https://pubmed.ncbi.nlm.nih.gov/36797421/ |
| Impact of nucleic acid extraction procedures on human papillomavirus (HPV) detection and genotyping. Naegele K, Weissbach FH, Leuzinger K, Gosert R, Bubendorf L, Hirsch HH. J Med Virol. 2023 Feb;95(2):e28583. doi: 10.1002/jmv.28583.PMID: 36794677. 16.02.23 https://pubmed.ncbi.nlm.nih.gov/36794677/ |
| The alarmin interleukin-33 promotes the expansion and preserves the stemness of Tcf-1+ CD8+ T cells in chronic viral infection. AF Marx, Kallert SM, Brunner TM, Villega JA, Geier F, Fixemer J, Abreu-Mota T, Reuther P, Bonilla WV, Fadejeva J, Kreutzfeldt M, Wagner I, Aparicio-Domingo P, Scarpellino L, Charmoy M, Utzschneider DT, Hagedorn C, Lu M, Cornille K, Stauffer K, Kreppel F, Merkler D, Zehn D, Held W, Luther SA, Löhning M, D Pinschewer DD. Immunity. 2023 Feb 14;S1074-7613(23)00041-9. doi: 10.1016/j.immuni.2023.01.029. Online ahead of print. 14.02.23 https://pubmed.ncbi.nlm.nih.gov/36809763/ |
| Ketanserin Reverses the Acute Response to LSD in a Randomized, Double-Blind, Placebo-Controlled, Crossover Study in Healthy Participants. Becker AM, Klaiber A, Holze F, Istampoulouoglou I, Duthaler U, Varghese N, Eckert A, Liechti ME. Int J Neuropsychopharmacol. 2023 Feb 14;26(2):97-106. doi: 10.1093/ijnp/pyac075. 14.02.23 https://pubmed.ncbi.nlm.nih.gov/36342343/ |
| Human 3D nucleus pulposus microtissue model to evaluate the potential of pre-conditioned nasal chondrocytes for the repair of degenerated intervertebral disc. Kasamkattil J, Gryadunova A, Schmid R, Gay-Dujak MHP, Dasen B, Hilpert M, Pelttari K, Martin I, Schären S, Barbero A, Krupkova O, Mehrkens A. " Front Bioeng Biotechnol. 2023 Feb 14;11:1119009. doi: 10.3389/fbioe.2023.1119009. eCollection 2023. ". 14.02.23 https://pubmed.ncbi.nlm.nih.gov/36865027/ |
| MRGPRX2: A novel biomarker in mastocytosis? Konantz M, Merkel T, Meyer SC, Hartmann K. J Allergy Clin Immunol Pract. 2023 Feb;11(2):669-671. doi: 10.1016/j.jaip.2022.10.053. PMID: 36759088. 11.02.23 https://pubmed.ncbi.nlm.nih.gov/36759088/ |
| Serum Glial Fibrillary Acidic Protein Compared With Neurofilament Light Chain as a Biomarker for Disease Progression in Multiple Sclerosis. Meier S, Willemse EAJ, Schaedelin S, Oechtering J, Lorscheider J, Melie-Garcia L, Cagol A, Barakovic M, Galbusera R, Subramaniam S, Barro C, Abdelhak A, Thebault S, Achtnichts L, Lalive P, Müller S, Pot C, Salmen A, Disanto G, Zecca C, D'Souza M, Orleth A, Khalil M, Buchmann A, Du Pasquier R, Yaldizli Ö, Derfuss T, Berger K, Hermesdorf M, Wiendl H, Piehl F, Battaglini M, Fischer U, Kappos L, Gobbi C, Granziera C, Bridel C, Leppert D, Maceski AM, Benkert P, Kuhle J. JAMA Neurol. 2023 Feb 6;80(3):287-297. doi: 10.1001/jamaneurol.2022.5250. Online ahead of print. 06.02.23 https://pubmed.ncbi.nlm.nih.gov/36745446/ |
| The NFIA-ETO2 fusion blocks erythroid maturation and induces pure erythroid leukemia in cooperation with mutant TP53. Piqué-Borràs MR, Jevtic Z, Otzen Bagger F, Seguin J, Sivalingam R, Bezerra MF, Louwaige A, Juge S, Nellas I, Ivanek R, Tzankov A, Moll U, Cantillo OV, Schulz-Heddergott R, Fagnan A, Mercher T, Schwaller J. Blood. 2023 Feb 3:blood.2022017273. doi: 10.1182/blood.2022017273. Online ahead of print. 03.02.23 https://www.sciencedirect.com/science/article/pii/S0006497123003105?via%3Dihub |
| Deletion of SNX9 alleviates CD8 T cell exhaustion for effective cellular cancer immunotherapy. Marcel P. Trefny, Nicole Kirchhammer, Priska Auf der Maur, Marina Natoli, Dominic Schmid, Markus Germann, Laura Fernandez Rodriguez, Petra Herzig, Jonas Lötscher, Maryam Akrami, Jane C. Stinchcombe, Michal A. Stanczak, Andreas Zingg, Melanie Buchi, Julien Roux, Romina Marone, Leyla Don, Didier Lardinois, Mark Wiese, Lukas T. Jeker, Mohamed Bentires-Alj, Jérémie Rossy, Daniela S. Thommen, Gillian M. Griffiths, Heinz Läubli, Christoph Hess, Alfred Zippelius. Nat Commun 14, 86 (2023). https://doi.org/10.1038/s41467-022-35583-w. 02.02.23 https://www.nature.com/articles/s41467-022-35583-w |
| A patient-centric modeling framework captures recovery from SARS-CoV-2 infection. Ruffieux H, Hanson AL, Lodge S, Lawler NG, Whiley L, Gray N, Nolan TH, Bergamaschi L, Mescia F, Turner L, de Sa A, Pelly VS, The Cambridge Institute of Therapeutic Immunology and Infectious Disease-National Institute of Health Research (CITIID-NIHR) BioResource COVID-19 Collaboration*, Kotagiri P, Kingston N, Bradley JR, Holmes E, Wist J, Nicholson JK, Lyons PA, Smith KGC, Richardson S, Bantug GR & Hess C. Nat Immunol. 2023 Feb;24(2):349-358. doi: 10.1038/s41590-022-01380-2. Epub 2023 Jan 30. 30.01.23 https://pubmed.ncbi.nlm.nih.gov/36717723/ |
| Soluble amyloid-β precursor peptide does not regulate GABAB receptor activity. Rem PD, Sereikaite V, Fernández-Fernández D, Reinartz S, Ulrich D, Fritzius T, Trovo L, Roux S, Chen Z, Rondard P, Pin JP, Schwenk J, Fakler B, Gassmann M, Rinaldi Barkat T, Strømgaard K, Bettler B. Elife. 2023 Jan 23;12:e82082. doi: 10.7554/eLife.82082. 23.01.23 https://pubmed.ncbi.nlm.nih.gov/36688536/ |
| Classic psychedelics do not affect T cell and monocyte immune responses. Rudin D, Areesanan A, Liechti ME and Gründemann C. Front Psychiatry. 2023 Jan 20;14:1042440. doi: 10.3389/fpsyt.2023.1042440. eCollection 2023. 20.01.23 https://pubmed.ncbi.nlm.nih.gov/36741125/ |
| Investigation of morpholine isosters for the development of a potent, selective and metabolically stable mTOR kinase inhibitor. De Pascale M, Bissegger L, Tarantelli C, Beaufils F, Prescimone A, Hedad HMS, Kayali O, Orbegozo C, Raguž L, Schaefer T, Hebeisen P, Bertoni F, Wymann MP, Borsari C. European Journal of Medicinal Chemistry. Volume 248, 15 February 2023, 115038, doi: 10.1016/j.ejmech.2022.115038. 28.12.22 |
| Engineering of immunoinstructive extracellular matrices for enhanced osteoinductivity. Garcia-Garcia A, Pigeot S, Martin I. Bioactive Materials, 24: 174-184 (2023). doi: 10.1016/j.bioactmat.2022.12.017. PMID: 36606254. 21.12.22 https://pubmed.ncbi.nlm.nih.gov/36606254/ |
| Liraglutide Lowers Endothelial Vascular Cell Adhesion Molecule-1 in Murine Atherosclerosis Independent of Glucose Levels. Punjabi M, Kosareva A, Xu L, Ochoa-Espinosa A, Decembrini S, Hofmann G, Wyttenbach S, Rolin B, Nyberg M, Kaufmann BA. JACC Basic Transl Sci. 2022 Dec 7;8(2):189-200. doi: 10.1016/j.jacbts.2022.08.002. eCollection 2023 Feb. 07.12.23 https://www.sciencedirect.com/science/article/pii/S2452302X22003023 |
| BK Polyomavirus Consensus. Hirsch HH, Mengel M, Kamar N. Clinical Infectious Diseases. Clin Infect Dis. 2022 Nov 30;75(11):2046-2047. doi: 10.1093/cid/ciac594. 30.11.22 https://pubmed.ncbi.nlm.nih.gov/35856634/ |
| Mini- and macro-scale direct perfusion bioreactors with optimized flow for engineering 3D tissues. Born G, Plantier E, Nannini G, Caimi A, Mazzoleni A, Asnaghi MA, Muraro MG, Scherberich A, Martin I, García-García A. Biotechnol. Feb;18(2): e2200405. doi: 10.1002/biot.202200405. Epub Feb 2023. doi: 10.1002/biot.202200405. PMID 36428229. 25.11.22 https://pubmed.ncbi.nlm.nih.gov/36428229/ |
| Defective Desmosomal Adhesion Causes Arrhythmogenic Cardiomyopathy by Involving an Integrin-αVβ6/TGF-β Signaling Cascade. Schinner C, Xu L, Franz H, Zimmermann A, Wanuske MT, Rathod M, Hanns P, Geier F, Pelczar P, Liang Y, Lorenz V, Stüdle C, Maly PI, Kauferstein S, Beckmann BM, Sheikh F, Kuster GM, Spindler V. Circulation. Circulation. 2022 Nov 22;146(21):1610-1626. doi: 10.1161/CIRCULATIONAHA.121.057329. 22.11.22 https://pubmed.ncbi.nlm.nih.gov/36268721/ |
| Molecular Characterization of BK Polyomavirus Replication in Allogeneic Hematopoietic Cell Transplantation. Leuzinger K, Kaur A, Wilhelm M, Frank K, Hillenbrand CA, Weissbach FH, Hirsch HH. The Journal of Infectious Diseases. J Infect Dis. 2022 Nov 21;jiac450. doi: 10.1093/infdis/jiac450. Online ahead of print. 21.11.22 https://pubmed.ncbi.nlm.nih.gov/36409589/ |
| Deciphering molecular and cellular ex vivo responses to bispecific antibodies PD1-TIM3 and PD1-LAG3 in human tumors. Natoli M, Hatje K, Gulati P, Junker F, Herzig P, Jiang Z, Davydov II, Germann M, Trüb M, Marbach D, Zwick A, Weber P, Seeber S, Wiese M, Lardinois D, Heinzelmann-Schwarz V, Rosenberg R, Tietze L, Mertz KD, Umaña P, Klein C, Codarri-Deak L, Kao H, Zippelius A. Journal for Immunotherapy of Cancer. J Immunother Cancer. 2022 Nov;10(11):e005548. doi: 10.1136/jitc-2022-005548. 10.11.22 https://pubmed.ncbi.nlm.nih.gov/36319064/ |
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| Review: Combination cancer immunotherapies: Emerging treatment strategies adapted to the tumor microenvironment. Kirchhammer N, Trefny MP, Auf der Maur P, Läubli H, Zippelius A. Science Translational Medicine. Sci Transl Med. 2022 Nov 9;14(670):eabo3605. doi: 10.1126/scitranslmed.abo3605. Epub 2022 Nov 9. 09.11.22 https://pubmed.ncbi.nlm.nih.gov/36350989/ |
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| Nose to Spine: spheroids generated by human nasal chondrocytes for scaffold-free nucleus pulposus augmentation. Gryadunova A, Kasamkattil J, Gay MHP, Dasen B, Pelttari K, Mironov V, Martin I, Schären S, Barbero A, Krupkova O, Mehrkens A. Acta Biomater. 134: 240-251 (2021). https://www.sciencedirect.com/science/article/pii/S174270612100502X?via%3Dihub |
| The Genomic Landscape of Serrated Lesion of the Colorectum: Similarities and Differences With Tubular and Tubulovillous Adenomas. Tornillo L, Lehmann FS, Garofoli A, Paradiso V, Ng CKY, Piscuoglio S. Front Oncol. 2021 Oct 12;11:668466. https://www.frontiersin.org/articles/10.3389/fonc.2021.668466/full |
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