Publications
Below you can find a recent publication list of the Department of Biomedicine.
If you are looking for publications of a specific group please refer to the corresponding research group.
August 2021 - September 2023
| An International Society for Cell and Gene Therapy Mesenchymal Stromal Cells (MSC) Committee perspectives on International Standards Organization/Technical Committee 276 Biobanking Standards for bone marrow-MSCs and umbilical cord tissue-derived MSCs for research purposes. S Viswanathan, K Le Blanc, R Ciccocioppo, G Dagher, AJ Filiano, J Galipeau, M Krampera, L Krieger, MM Lalu, J Nolta, VM Rodriguez Pardo, Y Shi, K Tarte, DJ Weiss, I Martin. Cytotherapy 2023 Aug; 25(8):803-807. doi: 10.1016/j.jcyt.2023.04.005. IF 4.5 www.isct-cytotherapy.org/article/S1465-3249(23)00100-7/fulltext |
| Immunoglobulin A Antibodies Against Myelin Oligodendrocyte Glycoprotein in a Subgroup of Patients With Central Nervous System Demyelination. AB Ayroza Galvão Ribeiro Gomes, L Kulsvehagen, P Lipps, A Cagol, N Cerdá-Fuertes, T Neziraj, J Flammer, J Lerner, AC Lecourt, N de Oliveira S Siebenborn, R Cortese, S Schaedelin, V Andreoli Schoeps, A de Moura Brasil Matos, N Trombini Mendes, C Dos Reis Pereira, ML Ribeiro Monteiro, SL Dos Apóstolos-Pereira, P Schindler, C Chien, C Schwake, R Schneider, T Pakeerathan, O Aktas, U Fischer, M Mehling, T Derfuss, L Kappos, I Ayzenberg, M Ringelstein, F Paul, D Callegaro, J Kuhle, A Papadopoulou, C Granziera, AK Pröbstel. JAMA Neurol. 2023 Aug 7:e232523. doi: 10.1001/jamaneurol.2023.2523. Online ahead of print.PMID: 37548987. IF 29 jamanetwork.com/journals/jamaneurology/fullarticle/2808235 |
| Serum neurofilament light chain reference database for individual application in paediatric care: a retrospective modelling and validation study. A Abdelhak, F Petermeier, P Benkert, S Schädelin, J Oechtering, A M Maceski, M Kabesch, T Geis, O Laub, G Leipold, C Gobbi, C Zecca, A Green, H Tumani, E Willemse, H Wiendl, C Granziera, L Kappos, D Leppert, E Waubant, S Wellmann, J Kuhle. Lancet Neurol. 2023 Sep;22(9):826-833. doi: 10.1016/S1474-4422(23)00210-7. Epub 2023 Jul 28. IF 48 www.sciencedirect.com/science/article/pii/S1474442223002107 |
| Targeting the Siglec–sialic acid axis promotes antitumor immune responses in preclinical models of glioblastoma. P Schmassmann, J Roux, A Buck, N Tatari, S Hogan, J Wang, N R Mantuano, R Wieboldt, S Lee, B Snijder, D Kaymak, T A Martins, M F Ritz, T Shekarian, M Mcdaid, M Weller, T Weiss, H Läubli, G Hutter. DOI: 10.1126/scitranslmed.adf5302. IF 17.1 www.science.org/doi/10.1126/scitranslmed.adf5302 |
| Failure of cartilage regeneration: emerging hypotheses and related therapeutic strategies. S Muthu, JV Korpershoek, EJ Novais, GF Tawy, AP Hollander, I Martin. Nat Rev Rheumatol. 2023 July 19;19(7):403-416 (2023). doi: 10.1038/s41584-023-00979-5. IF 33.7 www.nature.com/articles/s41584-023-00979-5 |
| Targeting the Siglec–sialic acid axis promotes antitumor immune responses in preclinical models of glioblastoma. P Schmassmann, J Roux, A Buck, N Tatari, S Hogan, J Wang, N Rodrigues Mantuano, R Wieboldt, S Lee, B Snijder, D Kaymak, T A Martins, M.-F. Ritz, T Shekarian, M McDaid, M Weller, T Weiss, H Läubli, G Hutter. Sci Transl Med. 2023 Jul 19;15(705):eadf5302. doi: 10.1126/scitranslmed.adf5302. Epub 2023 Jul 19. IF 17.1 www.science.org/doi/10.1126/scitranslmed.adf5302 |
| Increased TIM-3 and GAL-9 serum levels in patients with advanced systemic mastocytosis. M Konantz, M Williams, T Merkel, A Reiss, S Dirnhofer, S C Meyer, P Valent, T I George, A Tzankov, K Hartmann. Journal of Allergy and Clinical Immunology, 2023, ISSN 0091-6749, doi.org/10.1016/j.jaci.2023.07.001. IF 14.2 www.sciencedirect.com/science/article/pii/S0091674923008606 |
| Upscaled Skeletal Muscle Engineered Tissue with In Vivo Vascularization and Innervation Potential. V Borisov, L Sole, G Reid, G Milan, G Hutter, M Grapow, F S Eckstein, G Isu, A Marsano. Bioengineering 2023, 10(7), 800; doi.org/10.3390/bioengineering10070800. IF 4.6 www.mdpi.com/2306-5354/10/7/800 |
| ER-mitochondria contacts and cholesterol metabolism are disrupted by disease-associated tau protein. L Szabo, N Cummins, P Paganetti, A Odermatt, A Papassotiropoulos, C Karch, J Götz, A Eckert, A Grimm. EMBO Rep. 2023 Aug 3;24(8):e57499. doi: 10.15252/embr.202357499. Epub 2023 Jul 4.PMID: 37401859. IF 7.7 www.embopress.org/doi/full/10.15252/embr.202357499 |
| Diesel Exhaust Particle (DEP)-induced glucose intolerance is driven by an intestinal innate immune response and NLRP3 activation in mice. A J T Bosch, T V Rohm, S AlAsfoor, A J Y L, Z Baumann, N Parayil, F Noreen, J Roux, D T Meier, C Cavelti-Weder. Part Fibre Toxicol 20, 25 (2023). doi.org/10.1186/s12989-023-00536-8. IF 10 particleandfibretoxicology.biomedcentral.com/articles/10.1186/s12989-023-00536-8 |
| Nicotinamide N-methyltransferase sustains a core epigenetic program that promotes metastatic colonization in breast cancer. J Pinto Couto, M Vulin, C Jehanno, MM Coissieux, B Hamelin, A Schmidt, R Ivanek, A Sethi, K Brautigam, A L Frei, C Hager, M Manivannan, J Gomez-Miragaya, M MS Obradović, Z Varga, V H Koelzer, K D Mertz, M Bentires-Al. EMBO J. 2023 Jul 3;42(13):e112559. doi: 10.15252/embj.2022112559. Epub 2023 Jun 1. IF 11.4 www.embopress.org/doi/full/10.15252/embj.2022112559 |
| A method for polyclonal antigen-specific T cell-targeted genome editing (TarGET) for adoptive cell transfer applications. D Palianina, R B Di Roberto, R Castellanos-Rueda, F Schlatter, S T Reddy, N Khanna. Molecular Therapy - Methods & Clinical Development, Volume 30, 2023, Pages 147-160, ISSN 2329-0501, doi.org/10.1016/j.omtm.2023.06.007. IF 12.4 www.sciencedirect.com/science/article/pii/S2329050123000979 |
| First-line treatment of unresectable or metastatic HER2 positive esophagogastric adenocarcinoma: liquid biomarker analysis of the phase 2 INTEGA trial. L Paschold, A Stein, B Thiele, J Tintelnot, S S Henkes, C Coith, C Schultheiß, K Pantel, S Riethdorf, M Binder. Journal for ImmunoTherapy of Cancer 2023;11:e006678. doi: 10.1136/jitc-2023-006678 IF 10.9 jitc.bmj.com/content/11/6/e006678 |
| Randomized Trial to Assess the Clinical Utility of Renal Allograft Monitoring by Urine CXCL10 Chemokine. P Hirt-Minkowski, J Handschin, S Stampf, H Hopfer, T Menter, L Senn, G Hönger, C Wehmeier, P Amico, J Steiger, M Koller, M Dickenmann, S Schaub. J Am Soc Nephrol. 2023 Aug 1;34(8):1456-1469. doi: 10.1681/ASN.0000000000000160. Epub 2023 May 25. PMID: 37228005. IF 13.6 journals.lww.com/jasn/Fulltext/2023/08000/Randomized_Trial_to_Assess_the_Clinical_Utility_of.16.aspx |
| Dual TLR9 and PD-L1 targeting unleashes dendritic cells to induce durable antitumor immunity. L Fernandez-Rodriguez, C Cianciaruso. R Bill, MP Trefny, R Klar, N Kirchhammer, M Buchi, J Festag, S Michel, R Kohler, E Jones, A Maaske, A Kashyap, F Jaschinski, K Dixon, M Pittet and A Zippelius. J Immunother Cancer. 2023 May;11(5):e006714. doi: 10.1136/jitc-2023-006714. IF 12.485 jitc.bmj.com/content/11/5/e006714 |
| HLA antibody affinity determination: From HLA-specific monoclonal antibodies to donor HLA specific antibodies (DSA) in patient serum. Hug MN, Keller S, Marty T, Gygax D, Meinel D, Spies P, Handschin J, Kleiser M, Vazquez N, Linnik J, Buchli R, Claas F, Heidt S, Kramer CSM, Bezstarosti S, Lee JH, Schaub S, Hönger G. HLA. 2023 May 16. doi: 10.1111/tan.15047. Epub ahead of print. PMID: 37191252. IF 8. onlinelibrary.wiley.com/doi/10.1111/tan.15047 |
| Generation of endogenously tagged E-cadherin cells using gene editing via non-homologous end joining. Rimmer N, Liang CY, Coelho R, Lopez MN, Jacob F. STAR Protoc. 2023 May 12;4(2):102305. doi: 10.1016/j.xpro.2023.102305. Online ahead of print.PMID: 37178110. IF 1.48 www.sciencedirect.com/science/article/pii/S2666166723002721 |
| Human epidermis organotypic cultures, a reproducible system recapitulating the epidermis in vitro. Experimental Dermatology. Rishika Agarwal, Tanja Dittmar, Hans-Dietmar Beer, Michael Kunz, Simon Müller, Elisabeth A. Kappos, Emmanuel Contassot, Alexander A. Navarini (2023). 2023;00:1-13. doi:10.1111/exd.14823 onlinelibrary.wiley.com/doi/10.1111/exd.14823 |
| "Impact of Clonal Architecture on Clinical Course and Prognosis in Patients With Myeloproliferative Neoplasms". D Luque Paz, M S Bader, R Nienhold, S Rai, T A Fonseca, J Stetka, H Hao-Shen, G Mild-Schneider, J R Passweg, R C Skoda. HemaSphere 7(5):p e885, May 2023. | DOI: 10.1097/HS9.0000000000000885. IF6.6 journals.lww.com/hemasphere/Fulltext/2023/05000/Impact_of_Clonal_Architecture_on_Clinical_Course.11.aspx |
| BK Polyomavirus Consensus. Hirsch HH, Mengel M, Kamar N. Clinical Infectious Diseases. Clin Infect Dis. 2022 Nov 30;75(11):2046-2047. doi: 10.1093/cid/ciac594. IF 20.999. 30.11.22 pubmed.ncbi.nlm.nih.gov/35856634/ |
| Defective Desmosomal Adhesion Causes Arrhythmogenic Cardiomyopathy by Involving an Integrin-αVβ6/TGF-β Signaling Cascade. Schinner C, Xu L, Franz H, Zimmermann A, Wanuske MT, Rathod M, Hanns P, Geier F, Pelczar P, Liang Y, Lorenz V, Stüdle C, Maly PI, Kauferstein S, Beckmann BM, Sheikh F, Kuster GM, Spindler V. Circulation. Circulation. 2022 Nov 22;146(21):1610-1626. doi: 10.1161/CIRCULATIONAHA.121.057329. IF 39.918. 22.11.22 pubmed.ncbi.nlm.nih.gov/36268721/ |
| Molecular Characterization of BK Polyomavirus Replication in Allogeneic Hematopoietic Cell Transplantation. Leuzinger K, Kaur A, Wilhelm M, Frank K, Hillenbrand CA, Weissbach FH, Hirsch HH. The Journal of Infectious Diseases. J Infect Dis. 2022 Nov 21;jiac450. doi: 10.1093/infdis/jiac450. Online ahead of print. IF 5.838. 21.11.22 pubmed.ncbi.nlm.nih.gov/36409589/ |
| Deciphering molecular and cellular ex vivo responses to bispecific antibodies PD1-TIM3 and PD1-LAG3 in human tumors. Natoli M, Hatje K, Gulati P, Junker F, Herzig P, Jiang Z, Davydov II, Germann M, Trüb M, Marbach D, Zwick A, Weber P, Seeber S, Wiese M, Lardinois D, Heinzelmann-Schwarz V, Rosenberg R, Tietze L, Mertz KD, Umaña P, Klein C, Codarri-Deak L, Kao H, Zippelius A. Journal for Immunotherapy of Cancer. J Immunother Cancer. 2022 Nov;10(11):e005548. doi: 10.1136/jitc-2022-005548. IF 12.485. 10.11.22 pubmed.ncbi.nlm.nih.gov/36319064/ |
| Severe Neuro-COVID is associated with peripheral immune signatures, autoimmunity and neurodegeneration: a prospective cross-sectional study. Etter MM, Martins TA, Kulsvehagen L, Pössnecker E, Duchemin W, Hogan S, Sanabria-Diaz G, Müller J, Chiappini A, Rychen J, Eberhard N, Guzman R, Mariani L, Melie-Garcia L, Keller E, Jelcic I, Pargger H, Siegemund M, Kuhle J, Oechtering J, Eich C, Tzankov A, Matter MS, Uzun S, Yaldizli Ö, Lieb JM, Psychogios MN, Leuzinger K, Hirsch HH, Granziera C, Pröbstel AK, Hutter G. Nature Communications. Nat Commun. 2022 Nov 9;13(1):6777. doi: 10.1038/s41467-022-34068-0. IF 17.694. 09.11.22 pubmed.ncbi.nlm.nih.gov/36351919/ |
| Review: Combination cancer immunotherapies: Emerging treatment strategies adapted to the tumor microenvironment. Kirchhammer N, Trefny MP, Auf der Maur P, Läubli H, Zippelius A. Science Translational Medicine. Sci Transl Med. 2022 Nov 9;14(670):eabo3605. doi: 10.1126/scitranslmed.abo3605. Epub 2022 Nov 9. IF 19.343. 09.11.22 pubmed.ncbi.nlm.nih.gov/36350989/ |
| Targeting cancer glycosylation repolarizes tumor-associated macrophages allowing effective immune checkpoint blockade. Stanczak MA, Mantuano NR, Kirchhammer N, Sanin DE, Jacob F, Coelho R, Everest-Dass AV, Wang J, Trefny MP, Monaco G, Bärenwaldt A, Gray MA, Petrone A, Kashyap AS, Glatz K, Kasenda B, Normington K, Broderick J, Peng L, Pearce OMT, Pearce EL, Bertozzi CR, Zippelius A, Läubli H. Science Translational Medicine. Transl Med. 2022 Nov 2;14(669):eabj1270. doi: 10.1126/scitranslmed.abj1270. Epub 2022 Nov 2. IF 19.343. 02.11.22 pubmed.ncbi.nlm.nih.gov/36322632/ |
| «Overlapping gene dependencies for PARP inhibitors and carboplatin response identified by functional CRISPR-Cas9 screening in ovarian cancer». Coelho R, Tozzi A, Disler M, Lombardo F, Fedier A, López MN, Freuler F, Jacob F, Heinzelmann-Schwarz V. Cell, Death and Disease. Death Dis. 2022 Oct 28;13(10):909. doi: 10.1038/s41419-022-05347-x. IF 9.696. 28.10.22 pubmed.ncbi.nlm.nih.gov/36307400/ |
| Forced expression of the non-coding RNA miR-17~92 restores activation and function in CD28-deficient CD4+ T cells. Dölz M, Hasiuk M, Gagnon JD, Kornete M, Marone R, Bantug G, Kageyama R, Hess C, Ansel KM, Seyres D, Roux J, T Jeker LT. iScience. Science. 2022 Oct 17;25(11):105372. doi: 10.1016/j.isci.2022.105372. eCollection 2022 Nov 18. IF 6.107. 17.10.22 pubmed.ncbi.nlm.nih.gov/36388982/ |
| Stereospecific Synthesis of Substituted Sulfamidates as Privileged Morpholine Building Blocks. Stojiljkovic, U., Meyer, C., Boulay, P., Hebeisen, P., Rageot, D., Wymann, M., Borsari, C. Synthesis. Synthesis 2022, Doi: 10.1055/a-1915-7794. IF 3.019. 10.10.22 dx.doi.org/10.1055/a-1915-7794 |
| Comment: Two-drug trick to target the brain blocks toxicity in the body. Wymann MP, Borsari C. Nature. Comment Nature. 2022 Sep;609(7928):681-683. doi: 10.1038/d41586-022-02892-5. IF 69.504. 14.09.22 www.nature.com/articles/d41586-022-02892-5 |
| Receptor clustering and pathogenic complement activation in myasthenia gravis depend on synergy between antibodies with multiple subunit specificities. Rose N, Holdermann S, Callegari I, Kim H, Fruh I, Kappos L, Kuhle J, Müller M, Sanderson NSR, Derfuss T. Acta Neuropathologica. Acta Neuropathol. 2022 Nov;144(5):1005-1025. IF 15.887. 08.09.22 pubmed.ncbi.nlm.nih.gov/36074148/ |
| Low Baseline but Not Delta Cortisol Relates to 28-Day Transplant-Free Survival in Acute and Acute-on-Chronic Liver Failure. Roth S, Flint E, Ghataore L, Patel VC, Singanayagam A, Vincent RP, Triantafyllou E, Ma Y, Bernal W, Auzinger G, Heneghan M, Antoniades C, Christ-Crain M, McPhail MJW, Taylor DR, Wendon J, Bernsmeier C. Gastro Hep Advances. Gastro Hep Advances. 2022. Vol 2(1). p72-82. Published online: September 03, 2022, DOI:https://doi.org/10.1016/j.gastha.2022.08.006. 05.09.22 pubmed.ncbi.nlm.nih.gov/35857639/ www.sciencedirect.com/science/article/pii/S2772572322001479 |
| Targeted transcript analysis in muscles from patients with genetically diverse congenital myopathies. Bachmann C, Franchini M, Van den Bersselaar LR, Kruijt N, Voermans NC, Bouman K, Kamsteeg EJ, Knop KC, Ruggiero L, Santoro L, Nevo Y, Wilmshurst J, Vissing J, Sinnreich M, Zorzato D, Muntoni F, Jungbluth H, Zorzato F, Treves S. Brain Communications. Brain Communications, Volume 4, Issue 5, 2022, fcac224, doi.org/10.1093/braincomms/fcac224. IF 1.010. 02.09.22 academic.oup.com/braincomms/article/4/5/fcac224/6687656 |
| Small-diameter bacterial cellulose-based vascular grafts for coronary artery bypass grafting in a pig model. Fusco D, Meissner F, Podesser BK, Marsano A, Grapow M, Eckstein F, Winkler B. frontiers. Front Cardiovasc Med. 2022 Sep 26;9:881557. doi: 10.3389/fcvm.2022.881557. eCollection 2022. IF 5.848. 26.08.22 pubmed.ncbi.nlm.nih.gov/36225961/ |
| Mycobacterium abscessus pathogenesis identified by phenogenomic analyses. Boeck L, Burbaud S, Skwark M, Pearson WH, Sangen J, Wuest AW, Marshall EKP, Weimann A, Everall I, Bryant JM, Malhotra S, Bannerman BP, Kierdorf K, Blundell TL, Dionne MS, Parkhill J, Andres Floto R. Nature Microbiology. Nat Microbiol. 2022 Sep;7(9):1431-1441. IF 30.964. 25.08.22. www.nature.com/articles/s41564-022-01204-x |
| Review: Siglec receptors as new immune checkpoints in cancer. Stanczak MA, Läubli H. Molecular Aspects of Medicine. Mol Aspects Med. 2022 Aug 7;101112. doi: 10.1016/j.mam.2022.101112. IF 16.337. 07.08.22 pubmed.ncbi.nlm.nih.gov/35948467/ |
| C1q as a target molecule to treat human disease: What do mouse studies teach us? Schulz K, Trendelenburg M. Front Immunol. Front Immunol. 2022 Aug 3;13:958273. doi: 10.3389/fimmu.2022.958273. IF 8.787. 03.08.22 pubmed.ncbi.nlm.nih.gov/35990646/ |
| Anti-C1q autoantibodies from systemic lupus erythematosus patients enhance CD40-CD154-mediated inflammation in peripheral blood mononuclear cells invitro. Rabatscher PA, Trendelenburg M. Clinical & Translational Immunology. Clin Transl Immunology. 2022 Aug 2;11(8):e1408. doi: 10.1002/cti2.1408. IF 6.515. 02.08.22 pubmed.ncbi.nlm.nih.gov/35928801/ |
| NK cells with tissue-resident traits shape response to immunotherapy by inducing adaptive antitumor immunity. Kirchhammer N, Trefny MP, Natoli M, Brücher D, Smith SN, Werner F, Koch V, Schreiner D, Bartoszek E, Buchi M, Schmid M, Breu D, Hartmann KP, Zaytseva P, Thommen DS, Läubli H, Böttcher JP, Stanczak MA, Kashyap AS, Plückthun A, Zippelius A. Science Translational Medicine. Sci Transl Med. 2022 Jul 13;14(653):eabm9043. doi: 10.1126/scitranslmed.abm9043. Epub 2022 Jul 13. IF 19.343. 13.07.22 pubmed.ncbi.nlm.nih.gov/35857639/ |
| Safe administration of subsequent mRNA COVID-19 vaccine doses following a possible allergic reaction to the first dose. Roth MS, Chantraine S, Morales Mateluna CA, Hartmann K*, Berger CT* (*equally). The Journal of the European Academy of Dermatology and Venereology. J Eur Acad Dermatol Venereol. 2022 Nov;36(11):e880-e883. doi: 10.1111/jdv.18387. Epub 2022 Jul 12. IF 9.228. 20.06.22 onlinelibrary.wiley.com/doi/10.1111/jdv.18387 |
| Integrative proteogenomic characterization of hepatocellular carcinoma across etiologies and stages. Ng CKY, Dazert E, Boldanova T, Coto-Llerena M, Nuciforo S, Ercan C, Suslov A, Meier MA, Bock T, Schmidt A, Ketterer S, Wang X, Wieland S, Matter MS, Colombi M, Piscuoglio S, Terracciano LM, Hall MN, Heim MH. Nat Commun. 2022 May 4;13(1):2436. IF 14.919 www.nature.com/articles/s41467-022-29960-8 |
| Alterations in homologous recombination repair genes in prostate cancer brain metastases. Rodriguez-Calero A, Gallon J, Akhoundova D, Maletti S, Ferguson A, Cyrta J, Amstutz U, Garofoli A, Paradiso V, Tomlins SA, Hewer E, Genitsch V, Fleischmann A, Vassella E, Rushing EJ, Grobholz R, Fischer I, Jochum W, Cathomas G, Osunkoya AO, Bubendorf L, Moch H, Thalmann G, Ng CKY, Gillessen S, Piscuoglio S, Rubin MA. Nat Commun. 2022 May 3;13(1):2400. IF 14.919 www.nature.com/articles/s41467-022-30003-5.pdf |
| Targeting colonic macrophages improves glycemic control in high-fat diet-induced obesity. Rohm TV, Keller L, Bosch AJT, AlAsfoor S, Baumann Z, Thomas A, Wiedemann SJ, Steiger L, Dalmas E, Wehner J, Rachid L, Mooser C, Yilmaz B, Fernandez Trigo N, Jauch AJ, Wueest S, Konrad D, Henri S, Niess JH, Hruz P, Ganal-Vonarburg SC, Roux J, Meier DT, Cavelti-Weder C. Commun Biol. 2022 Apr 19;5(1):370. IF 6.268 www.nature.com/articles/s42003-022-03305-z |
| Identification of TPM2 and CNN1 as Novel Prognostic Markers in Functionally Characterized Human Colon Cancer-Associated Stromal Cells. Mele V, Basso C, Governa V, Glaus Garzon JF, Muraro MG, Däster S, Nebiker CA, Mechera R, Bolli M, Schmidt A, Geiger R, Spagnoli GC, Christoforidis D, Majno PE, Borsig L, Iezzi G. Cancers (Basel). 2022 Apr 16;14(8):2024. IF: 6.639 www.ncbi.nlm.nih.gov/pmc/articles/PMC9025001/ |
| Covalent Proximity Scanning of a Distal Cysteine to Target PI3Kα. Borsari C, Keles E, McPhail JA, Schaefer A, Sriramaratnam R, Goch W, Schaefer T, De Pascale M, Bal W, Gstaiger M, Burke JE, Wymann MP. J Am Chem Soc. 2022 Apr 13;144(14):6326-6342. IF 15.419 pubs.acs.org/doi/10.1021/jacs.1c13568 |
| Serum neurofilament light chain for individual prognostication of disease activity in people with multiple sclerosis: a retrospective modelling and validation study. Benkert P, Meier S, Schaedelin S, Manouchehrinia A, Yaldizli Ö, Maceski A, Oechtering J, Achtnichts L, Conen D, Derfuss T, Lalive PH, Mueller C, Müller S, Naegelin Y, Oksenberg JR, Pot C, Salmen A, Willemse E, Kockum I, Blennow K, Zetterberg H, Gobbi C, Kappos L, Wiendl H, Berger K, Sormani MP, Granziera C, Piehl F, Leppert D, Kuhle J; NfL Reference Database in the Swiss Multiple Sclerosis Cohort Study Group. Lancet Neurol. 2022 Mar;21(3):246-257. IF: 44.182 www.sciencedirect.com/science/article/pii/S1474442222000096 |
| Determinants of SARS-CoV-2 transmission to guide vaccination strategy in an urban area. Brüningk SC, Klatt J, Stange M, Mari A, Brunner M, Roloff TC, Seth-Smith HMB, Schweitzer M, Leuzinger K, Søgaard KK, Albertos Torres D, Gensch A, Schlotterbeck AK, Nickel CH, Ritz N, Heininger U, Bielicki J, Rentsch K, Fuchs S, Bingisser R, Siegemund M, Pargger H, Ciardo D, Dubuis O, Buser A, Tschudin-Sutter S, Battegay M, Schneider-Sliwa R, Borgwardt KM, Hirsch HH, Egli A. Virus Evol. 2022 Mar 17;8(1):veac002. IF 7.98 academic.oup.com/ve/article/8/1/veac002/6549831 |
| Epithelial GPR35 protects from Citrobacter rodentium infection by preserving goblet cells and mucosal barrier integrity. Melhem H, Kaya B, Kaymak T, Wuggenig P, Flint E, Roux J, Oost KC, Cavelti-Weder C, Balmer ML, Walser JC, Morales RA, Riedel CU, Liberali P, Villablanca EJ, Niess JH. Mucosal Immunol. 2022 Mar;15(3):443-458. IF 7.313 www.nature.com/articles/s41385-022-00494-y |
| T-cadherin Expressing Cells in the Stromal Vascular Fraction of Human Adipose Tissue: Role in Osteogenesis and Angiogenesis. Guerrero J, Dasen B, Frismantiene A, Pigeot S, Ismail T, Schaefer DJ, Philippova M, Resink TJ, Martin I, Scherberich A. Stem Cells Transl Med. 11(2): 213-229 (2022). IF 6.940 academic.oup.com/stcltm/article/11/2/213/6544662 |
| Siglec receptors modulate dendritic cell activation and antigen presentation to T cells in cancer. Wang J, Manni M, Bärenwaldt A, Wieboldt R, Kirchhammer N, Ivanek R, Stanczak M, Zippelius A, König D, Rodrigues Manutano N, Läubli H. Front Cell Dev Biol. 2022 Mar 3;10:828916. IF 6.684 www.frontiersin.org/articles/10.3389/fcell.2022.828916/full |
| Improvement of muscle strength in a mouse model for congenital myopathy treated with HDAC and DNA methyltransferase inhibitors. Ruiz A, Benucci S, Duthaler U, Bachmann C, Franchini M, Noreen F, Pietrangelo L, Protasi F, Treves S, Zorzato F. eLife. 2022 Mar 3;11:e73718. IF 8.146 elifesciences.org/articles/73718 |
| Engineering of Tracheal Grafts Based on Recellularization of Laser-Engraved Human Airway Cartilage Substrates. Baranovskii D, Demner J, Nürnberger S, Lyundup A, Redl H, Hilpert M, Pigeot S, Krasheninnikov M, Krasilnikova O, Klabukov I, Parshin V, Martin I, Lardinois D, Barbero A. Cartilage. 1-12 (2022). IF 6.634 journals.sagepub.com/doi/10.1177/19476035221075951+ |
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| Nose to Spine: spheroids generated by human nasal chondrocytes for scaffold-free nucleus pulposus augmentation. Gryadunova A, Kasamkattil J, Gay MHP, Dasen B, Pelttari K, Mironov V, Martin I, Schären S, Barbero A, Krupkova O, Mehrkens A. Acta Biomater. 134: 240-251 (2021). IF 8.947 www.sciencedirect.com/science/article/pii/S174270612100502X |
| The Genomic Landscape of Serrated Lesion of the Colorectum: Similarities and Differences With Tubular and Tubulovillous Adenomas. Tornillo L, Lehmann FS, Garofoli A, Paradiso V, Ng CKY, Piscuoglio S. Front Oncol. 2021 Oct 12;11:668466. IF 6.244 www.frontiersin.org/articles/10.3389/fonc.2021.668466/full |
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| Engineering of fully humanized and vascularized 3D bone marrow niches sustaining undifferentiated human cord blood hematopoietic stem and progenitor cells. Born G, Nikolova M, Scherberich A, Treutlein B, García-García A, Martin I. J Tissue Eng. 12: 1-11 (2021). IF 7.813 journals.sagepub.com/doi/10.1177/20417314211044855 |
| Culturing patient-derived malignant hematopoietic stem cells in engineered and fully humanized 3D niches. García-García A, Klein T, Born G, Hilpert M, Scherberich A, Lengerke C, Skoda RC, Bourgine PE, Martin I. Proc Nat Acad Sci USA. 118(40), e2114227118: 1-10 (2021). IF 10.700 www.pnas.org/doi/10.1073/pnas.2114227118 |
| Spatial regulation by multiple Gremlin1 enhancers provides digit development with cis-regulatory robustness and evolutionary plasticity. Malkmus J, Ramos Martins L, Jhanwar S, Kircher B, Palacio V, Sheth R, Leal F, Duchesne A, Lopez-Rios J, Peterson KA, Reinhardt R, Onimaru K, Cohn MJ, Zuniga A, Zeller R. Nature Commun 12, 5557. IF 14.919 www.ncbi.nlm.nih.gov/pmc/articles/PMC8455560/ |
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| Manufacturing of Human Tissues as off-the-Shelf Grafts Programmed to Induce Regeneration. Pigeot S, Klein T, Gullotta F, Dupard SJ, Garcia Garcia A, García-García A, Prithiviraj S, Lorenzo P, Filippi M, Jaquiery C, Kouba L, Asnaghi MA, Raina DB, Dasen B, Isaksson H, Önnerfjord P, Tägil M, Bondanza A, Martin I, Bourgine PE. Adv Mater. 33, 2103737: 1-13 (2021). IF 30.849 onlinelibrary.wiley.com/doi/10.1002/adma.202103737 |
| Dual targeting of JAK2 and ERK interferes with the myeloproliferative neoplasm clone and enhances therapeutic efficacy. Brkic S, Stivala S, Santopolo A, Szybinski J, Jungius S, Passweg JR, Tsakiris D, Dirnhofer S, Hutter G, Leonards K, Lischer HEL, Dettmer MS, Neel BG, Levine RL, Meyer SC. Leukemia. 2021 Oct;35(10):2875-2884. IF 11.528 www.nature.com/articles/s41375-021-01391-2 |
| Engineered nasal cartilage for the repair of osteoarthritic knee cartilage defects. Acevedo Rua L, Mumme M, Manferdini C, Darwiche S, Khalil A, Hilpert M, Buchner DA, Lisignoli G, Occhetta P, von Rechenberg B, Haug M, Schaefer DJ, Jakob M, Caplan A, Martin I, Barbero A, Pelttari K. Sci Transl Med. 13(609), eaaz4499:1-14 (2021). IF 17.992 www.science.org/doi/10.1126/scitranslmed.aaz4499 |
| Persistent RNA virus infection is short-lived at the single-cell level but leaves transcriptomic footprints. Reuther P, Martin K, Kreutzfeldt M, Ciancaglini M, Geier F, Calabrese D, Merkler D, Pinschewer DD. J Exp Med. (2021) 218 (10): e20210408. IF 14.307 rupress.org/jem/article/218/10/e20210408/212556/Persistent-RNA-virus-infection-is-short-lived-at |
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| Thymus extracellular matrix-derived scaffolds support graft-resident thymopoesis and long-term in vitro culure of adult thymic epithelial cells. Asnaghi MA, Barthlott T, Gullotta F, Strusi V, Amovilli A, Hafen K, Srivastava G, Oertle P, Toni R, Wendt D, Holländer GA, Martin I. Adv Funct Mater 31(20):2010747 (1-15) (2021). IF 18.808 www.ncbi.nlm.nih.gov/pmc/articles/PMC8436951/ |
| Deep learning enables the automation of grading histological tissue engineered cartilage images for quality control standardization. Power L, Acevedo L, Yamashita R, Rubin D, Martin I, Barbero A. Osteoarthritis Cartilage. 29:433-443 (2021). IF 6.576 www.sciencedirect.com/science/article/pii/S1063458421000042 |
| Mass Cytometry of CSF Identifies an MS-Associated B-cell Population. Johansson D, Rauld C, Roux J, Regairaz C, Galli E, Callegari I, Raad L, Waldt A, Cuttat R, Roma G, Diebold M, Becher B, Kuhle J, Derfuss T, Carballido JM, Sanderson NSR. Neurol Neuroimmunol Neuroinflamm. 2021 Feb 15;8(2):e943. IF 8.485 nn.neurology.org/content/8/2/e943.long |
| Adenylosuccinate lyase is oncogenic in colorectal cancer by causing mitochondrial dysfunction and independent activation of NRF2 and mTOR-MYC-axis. Taha-Mehlitz S, Bianco G, Coto-Llerena M, Kancherla V, Bantug GR, Gallon J, Ercan C, Panebianco F, Eppenberger-Castori S, von Strauss M, Staubli S, Bolli M, Peterli R, Matter MS, Terracciano LM, von Flüe M, Ng CKY, Soysal SD, Kollmar O, Piscuoglio S. Theranostics. 2021 Feb 15;11(9):4011-4029. IF 11.556 www.thno.org/v11p4011.htm |
| Presence of SARS-CoV-2 transcripts in the choroid plexus independent of multiple sclerosis. Fuchs V, Kutza M, Wischnewski S, Deigendesch N, Lutz L, Kulsvehagen L, Ricken G, Kappos L, Tzankov A, Hametner S, Frank S, Schirmer L, Pröbstel AK. Neurol Neuroimmunol Neuroinflamm. 2021; 8(2):e957. IF 8.485 nn.neurology.org/content/8/2/e957.long |