Selected Publications
Please find below a selection of publications from the Department of Biomedicine.
If you are looking for publications of a specific group please refer to the corresponding research group.
August 2021 - April 2025
| Mitochondria regulate MR1 protein expression and produce self-metabolites that activate MR1-restricted T cells. Prota G, Berloffa G, Awad W, Vacchini A, Chancellor A, Schaefer V, Constantin D, Littler D.R., Colombo R, Nosi V, Mori L, Rossjohn J, De Libero G. Proc Natl Acad Sci U S A. 2025 May 20;122(20):e2418525122. doi: 10.1073/pnas.2418525122. Epub 2025 May 12. https://www.pnas.org/doi/10.1073/pnas.2418525122?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub++0pubmed | |
| Safety and Efficacy of Repeated Low-Dose LSD for ADHD Treatment in Adults: A Randomized Clinical Trial. Mueller L, Santos de Jesus J, Schmid Y, Müller F, Becker A, Klaiber A, Straumann I, Luethi D, Haijen E.C.H.M., Hurks P.P.M., Kuypers K.P.C., Liechti M.E. JAMA Psychiatry. 2025 Mar 19:e250044. doi: 10.1001/jamapsychiatry.2025.0044. Online ahead of print. https://jamanetwork.com/journals/jamapsychiatry/fullarticle/2831639 | |
| Toward Origami-Inspired In Vitro Cardiac Tissue Models. Sileo A, Montrone F, Rouchon A, Trueb D, Selvi J, Schmid M, Graef J, Züger F, Serino G , Massai D, Di Maggio N, Rodriguez G M, Köser J, Schoelkopf J, Banfi A, Marsano A, Gullo M. ACS Biomater Sci Eng. 2025 Mar 10;11(3):1583-1597. doi: 10.1021/acsbiomaterials.4c01594. Epub 2025 Feb 20. https://pubs.acs.org/doi/10.1021/acsbiomaterials.4c01594 | |
| Clinical relevance of engineered cartilage maturation in a randomized multicenter trial for articular cartilage repair. Mumme M, Wixmerten A, Ivkovic A, Peretti GM, Yilmaz T, Reppenhagen S, Pullig O, Miot S, Izadpanah K, Jakob M, Mangiavini L, Sosio C, Vuletić F, Bieri O, Biguzzi S, Gahl B, Lehoczky G, Vukojevic R, Häusner S, Gryadunova A, Haug M, Barbero A, Martin I. Sci Transl Med. 2025 Mar 5;17(788):eads0848. doi: 10.1126/scitranslmed.ads0848. Epub 2025 Mar 5. https://www.science.org/doi/10.1126/scitranslmed.ads0848 | |
| Active repression of cell fate plasticity by PROX1 safeguards hepatocyte identity and prevents liver tumorigenesis. Lim B, Kamal A, Gomez Ramos B, Segarra J.M.A., Ibarra I.L., Dignas L, Kindinger T, Volz K, Rahbari M, Rahbari N, Poisel E, Kafetzopoulou K, Böse L, Breinig M, Heide D, Gallage S, Avila J.E.B., Wiethoff H, Berest I, Schnabellehner S, Schneider M, Becker J, Helm D, Grimm D, Mäkinen T, Tschaharganeh D.F., Heikenwalder M., Zaugg J.B., Mall M. Nat Genet. 2025 Mar;57(3):668-679. doi: 10.1038/s41588-025-02081-w. Epub 2025 Feb 13. https://www.nature.com/articles/s41588-025-02081-w | |
| Background white noise increases neuronal activity by reducing membrane fluctuations and slow-wave oscillations in auditory cortex. Christensen RK, Studer F, Barkat TR. Prog Neurobiol. 2025 Mar:246:102720. doi: 10.1016/j.pneurobio.2025.102720. Epub 2025 Jan 24. https://pubmed.ncbi.nlm.nih.gov/39863149/ | |
| Occurrence of cellular senescence in chronic human shoulder tendinopathies and its attenuation ex vivo by inhibition of Enhancer of Zeste 2. Bühler D, Hilpert M, Barbero A, Müller SA, Martin I, Pelttari K. Bone Joint Res. 2025 Feb 25;14(2):143-154. doi: 10.1302/2046-3758.142.BJR-2023-0378.R2. https://pubmed.ncbi.nlm.nih.gov/39996291/ | |
| 5-aza-2-deoxycytidine improves skeletal muscle function in a mouse model for recessive RYR1-related congenital myopathy. Ruiz A, Noreen F, Meier H, Buczak K, Zorzato F, Treves S. Hum Mol Genet. 2025 Feb 13:ddaf021. doi: 10.1093/hmg/ddaf021. Online ahead of print. https://academic.oup.com/hmg/advance-article/doi/10.1093/hmg/ddaf021/8011499 | |
| Durable lymphocyte subset elimination upon a single dose of AAV-delivered depletion antibody dissects immune control of chronic viral infection. Kastner A.L., Marx A.-F., Dimitrova M, Abreu-Mota T, Ertuna Y.I., Bonilla W.V., Stauffer K, Künzli M, Wagner I, Kreutzfeldt M, Merkler D, Pinschewer D.D. Immunity. 2025 Feb 11;58(2):481-498.e10. doi: 10.1016/j.immuni.2024.11.021. Epub 2024 Dec 23. https://www.cell.com/immunity/pdfExtended/S1074-7613(24)00536-3 | |
| Adiponectin reduces immune checkpoint inhibitor-induced inflammation without blocking anti-tumor immunity. Braun LM, Giesler S, Andrieux G, Riemer R, Talvard-Balland N, Duquesne S, Rückert T, Unger S, Kreutmair S, Zwick M, Follo M, Hartmann A, Osswald N, Melchinger W, Chapman S, Hutchinson JA, Haferkamp S, Torster L, Kött J, Gebhardt C, Hellwig D, Karantzelis N, Wallrabenstein T, Lowinus T, Yücel M, Brehm N, Rawluk J, Pfeifer D, Bronsert P, Rogg M, Mattern S, Heikenwälder M, Fusco S, Malek NP, Singer S, Schmitt-Graeff A, Ceteci F, Greten FR, Blazar BR, Boerries M, Köhler N, Duyster J, Ihorst G, Lassmann S, Keye P, Minguet S, Schadendorf D, Ugurel S, Rafei-Shamsabadi D, Thimme R, Hasselblatt P, Bengsch B, Schell C, Pearce EL, Meiss F, Becher B, Funke-Lorenz C, Placke JM, Apostolova P, Zeiser R. Cancer Cell. 2025 Feb 10;43(2):269-291.e19. doi: 10.1016/j.ccell.2025.01.004. https://pubmed.ncbi.nlm.nih.gov/39933899/ | |
| Deficiency of adenosine deaminase 2 skews adaptive immune repertoires toward specific sets of T- and B-cell receptors. Schultheiß C, Schmidt-Barbo P, Paschold L, Esperanzate C, Behn A, Mikolajczyk R, Kastner D.L. , Aksentijevich I, Binder M. J Allergy Clin Immunol. 2025 Feb 7:S0091-6749(25)00124-1. doi: 10.1016/j.jaci.2025.01.032. Online ahead of print. https://www.jacionline.org/article/S0091-6749(25)00124-1/fulltext | |
| Blood-Based Biomarkers for Identifying Disease Activity in AQP4-IgG-Positive Neuromyelitis Optica Spectrum Disorder. Kim SH, Gomes ABAGR, Schindler P, Hyun JW, Kim KH, Lee DE, Schoeps VA, Matos AMB, Mendes NT, Apóstolos-Pereira SLD, Callegaro D, Lerner J, Benkert P, Kuhle J, Ruprecht K, Paul F, Pröbstel AK, Kim HJ. JAMA Neurol. 2025 Feb 1;82(2):168-175. doi: 10.1001/jamaneurol.2024.4400. https://pubmed.ncbi.nlm.nih.gov/39714824/ | |
| mTORC2 Regulates Actin Polymerization in Auditory Cells. Lanz M, Cortada M, Yu L, Levano S, Bodmer D. J Neurochem. 2025 Feb;169(2):e70012. doi: 10.1111/jnc.70012. https://pubmed.ncbi.nlm.nih.gov/39921391/ | |
| Single-cell profiling of penta- and tetradactyl mouse limb buds identifies mesenchymal progenitors controlling digit numbers and identities. Palacio V, Pancho A, Morabito A, Malkmus J, He Z, Soussi G, Zeller R, Treutlein B, Zuniga A. Nat Commun. 2025 Jan 31;16(1):1226. doi: 10.1038/s41467-025-56221-1. https://www.nature.com/articles/s41467-025-56221-1 | |
| A human metabolic map of pharmacological perturbations reveals drug modes of action. Schuhknecht L, Ortmayr K, Jänes J, Bläsi M, Panoussis E, Bors S, Dorčáková T, Fuhrer T, Beltrao P & Zampieri M. Nat Biotechnol. 2025 Jan 28. doi: 10.1038/s41587-024-02524-5. Online ahead of print. https://www.nature.com/articles/s41587-024-02524-5 | |
| Fedratinib and gandotinib induce apoptosis and enhance the efficacy of tyrosine kinase inhibitors in human mast cells. Makeeva A, Stivala S, Ratti E, Clauss L, Sheremeti E, Arock M, Konantz M, Hartmann K. Am J Cancer Res. 2025 Jan 15;15(1):84-98. doi: 10.62347/TYTU4465. eCollection 2025. https://pmc.ncbi.nlm.nih.gov/articles/PMC11815366/ | |
| Neurofilament Light Chain as a Discriminator of Disease Activity Status in MOG Antibody-Associated Disease. Gomes ABAGR, Kim SH, Pretzsch R, Kulsvehagen L, Schaedelin S, Lerner J, Wetzel NS, Benkert P, Maleska Maceski A, Hyun JW, Lecourt AC, Lipps P, Schoeps VA, Matos AMB, Mendes NT, Apóstolos-Pereira SL, Mehling M, Derfuss T, Kappos L, Callegaro D, Kuhle J, Kim HJ, Pröbstel AK. Neurol Neuroimmunol Neuroinflamm. 2025 Jan;12(1):e200347. doi: 10.1212/NXI.0000000000200347. Epub 2024 Dec 20. https://www.neurology.org/doi/10.1212/NXI.0000000000200347 | |
| Circulating Monocytes Upregulate CD52 and Sustain Innate Immune Function in Cirrhosis Unless Acute Decompensation Emerges. Geng A, Brenig RG, Roux J, Lütge M, Cheng H-W, Flint EE, Lussier POG, Meier M-A, Pop OT, Künzler-Heule P, Matter MS, Wendon J, McPhail MJW, Soysal S, Semela D, Heim M, Weston CJ, Ludewig B, Bernsmeier C. J Hepatol. 2025 Jan 10:S0168-8278(24)02818-6. doi: 10.1016/j. jhep.2024.12.031. Online ahead of print. https://www.sciencedirect.com/science/article/pii/S0168827824028186?via%3Dihub | |
| Multidimensional analysis of matched primary and recurrent glioblastoma identifies contributors to tumor recurrence influencing time to relapse. Shekarian T, Ritz MF, Hogan S, Martins T A, Schmassmann P, Gerber A, Roux J, Kaymak D, Durano C, Burger B, Matter M, Hutter G. J Neuropathol Exp Neurol. 2025 Jan 1;84(1):45-58. doi: 10.1093/jnen/nlae108. https://pubmed.ncbi.nlm.nih.gov/39423857/ | |
The Carbonyl Nucleobase Adduct M3Ade Is a Potent Antigen for Adaptive Polyclonal MR1-Restricted T Cells. Chancellor A, Constantin D, Berloffa G, Yang Q , Nosi V, Loureiro JP, Colombo R, Jakob RP, Joss D, Pfeffer M, De Simone G, Morabito A, Schaefer V, Vacchini A, Brunelli L, Montagna D, Heim M, Zippelius A, Davoli E, Häussinger D, Maier T, Mori L, De Libero G. Immunity. 2024 Dec 11:S1074-7613(24)00534-X. doi: 10.1016/j.immuni.2024.11.019. Online ahead of print https://www.sciencedirect.com/science/article/pii/S107476132400534X | |
Significant Nocturnal Wakefulness After Sleep Onset in Metabolic Dysfunction–Associated Steatotic Liver Disease Schaeffer S, Bogdanovic A, Hildebrandt T, Flint E, Geng A, Pecenko S, Lussier P, Strumberger MA, Meyer M, Weber J, Heim M, Cajochen C, Bernsmeier C. Front Netw Physiol. 2024 Dec 4:4:1458665. doi: 10.3389/fnetp.2024.1458665. eCollection 2024 https://www.frontiersin.org/journals/network-physiology/articles/10.3389/fnetp.2024.1458665/full | |
| BK Polyomavirus (BKPyV) Serotype-Specific Antibody Responses in Blood Donors and Kidney Transplant Recipients With and Without New-Onset BKPyV-DNAemia: A Swiss Transplant Cohort Study. Hillenbrand CA, Bani DA, Follonier O, Kaur A, Weissbach FH, Wernli M, Wilhelm M, Leuzinger K, Binet I, Bochud PY, Golshayan D, Hirzel C, Manuel O, Mueller NJ, Schaub S, Schachtner T, Van Delden C, Hirsch HH; Swiss Transplant Cohort Study. Am J Transplant. 2024 Nov 21:S1600-6135(24)00707-X. doi: 10.1016/j.ajt.2024.11.019. Online ahead of print. https://www.sciencedirect.com/science/article/pii/S160061352400707X?via%3Dihub | |
| Optimized Full-Spectrum Flow Cytometry Panel for Deep Immuno Phenotyping of Murine Lungs. Baumann Z, Wiethe C, Vecchi CM, Richina V, Lopes T, Bentires-Alj M. Cell Rep Methods. 2024 Nov 18;4(11):100885. doi: 10.1016/j. crmeth.2024.100885. Epub 2024 Oct 30. https://www.sciencedirect.com/science/article/pii/S2667237524002686?via%3Dihub | |
| Inhibition of Cbl-b Restores Effector Functions of Human Intratumoral NK Cells. Tundo S, Trefny M, Rodić A, Grueninger O, Brodmann N, Börsch A , Serger C, Fürst J, Buchi M, Buczak K, Müller A T, Sach-Peltason L, Don L, Herzig P, Lardinois D, Heinzelmann-Schwarz V, Mertz KD, Hojski A, Schaeuble K, Laubli H, Natoli M, Toso A, Luu TT, Zippelius A, Romagnani A. J Immunother Cancer. 2024 Nov 17;12(11):e009860. doi: 10.1136/jitc-2024-009860. https://jitc.bmj.com/content/12/11/e009860.long | |
| Rapid, Potent, and Persistent Covalent Chemical Probes to Deconvolute PI3Kα Signaling. Bissegger L, Constantin Th A, Keles E, Raguž L, Barlow-Busch I, Orbegozo C, Schaefer T, Borlandelli V, Bohnacker T, Sriramaratnam R, Schäfer A, Gstaiger M, Burke J E, Borsari C, Wymann M P. Chem Sci. 2024 Nov 12. doi:10.1039/d4sc05459h. Online ahead of print. https://pubs.rsc.org/en/Content/ArticleLanding/2024/SC/D4SC05459H | |
Enhancing Anti-EGFRvIII CAR T Cell Therapy Against Glioblastoma With a Paracrine SIRPγ-Derived CD47 Blocker. Martins T A, Kaymak D, Tatari N, Gerster F, Hogan S, Ritz M-F, Sabatino V, Wieboldt R, Bartoszek E M, McDaid M, Gerber A, Buck A, Beshirova A, Heider A , Shekarian T, Mohamed H, Etter M M, Schmassmann P, Abel I, Boulay J-B, Saito Y, Mariani L, Guzman R, Snijder B, Weiss T, Läubli H, Hutter G. Nat Commun. 2024 Nov 9;15(1):9718. doi: 10.1038/s41467-024-54129-w. https://www.nature.com/articles/s41467-024-54129-w | |
| Single-Cell RNA-Sequencing of BK Polyomavirus Replication in Primary Human Renal Proximal Tubular Epithelial Cells Identifies Specific Transcriptome Signatures and a Novel Mitochondrial Stress Pattern. Weissbach FH, Follonier OM, Schmid S, Leuzinger K, Schmid M, Hirsch HH. J Virol. 2024 Nov 8:e0138224. doi: 10.1128/jvi.01382-24. Online ahead of print. https://journals.asm.org/doi/10.1128/jvi.01382-24 | |
The Effect of Fampridine on Working Memory: a Randomized Controlled Trial Based on a Genome-Guided Repurposing Approach Papassotiropoulos. A, Freytag V, Schicktanz N, Gerhards Ch, Aerni A, Faludi T, Amini E, Müggler E, Harings-Kaim A, Schlitt T, de Quervain D J-F. Mol Psychiatry. 2024 Nov 8. doi:10.1038/s41380-024-02820-1. Online ahead of print. https://www.nature.com/articles/s41380-024-02820-1 | |
| Nuclear and cytosolic fractions of SOX2 synergize as transcriptional and translational co-regulators of cell fate. Schaefer, T, Mittal, N, Wang, H, Ataman, M, Candido, S, Lötscher, J, Velychko, S, Tintignac, L, Bock, T, Börsch, A, Baßler, J, Rao, T. N., Zmajkovic, J, Roffeis, S, Löliger, J, Jacob, F, Dumlin, A, Schürch, C, Schmidt, A, Skoda, R. C., Wymann, M. P., Hess, C, Schöler, H. R., Zaehres, H, Hurt, E, Zavolan, M, Lengerke, C. Cell Rep. 2024 Oct 22;43(10):114807. doi: 10.1016/j.celrep.2024.114807. Epub 2024 Oct 3. https://www.sciencedirect.com/science/article/pii/S2211124724011586?via%3Dihub | |
| Mitochondrial-Derived Peptides, HNG and SHLP3, Protect Cochlear Hair Cells Against Gentamicin. Levano S, Yu L, Bartoszek E, Cortada M, Bodmer D. Cell Death Discov. 2024 Oct 21;10(1):445. doi: 10.1038/s41420-024-02215-9. https://www.nature.com/articles/s41420-024-02215-9 | |
| Multidimensional Analysis of Matched Primary and Recurrent Glioblastoma Identifies Contributors to Tumor Recurrence Influencing Time to Relapse. Shekarian T, Ritz M-F, Hogan S, Martins T A, Schmassmann P, Gerber A, Roux J, Kaymak D, Durano C, Burger B, Matter M, Hutter G. J Neuropathol Exp Neurol. 2024 Oct 18:nlae108. doi: 10.1093/jnen/nlae108. Online ahead of print. https://academic.oup.com/jnen/article/84/1/45/7826743?login=true | |
| Ablation of PC1/3 in POMC-Expressing Tissues but Not in Immune Cells Induces Sepsis Hypersensitivity. Moeller J, Meier D T. J Endocr Soc. 2024 Oct 3;8(11):bvae171. doi: 10.1210/jendso/bvae171. eCollection 2024 Sep 26. https://pubmed.ncbi.nlm.nih.gov/39435302/ | |
| MR1 Gene and Protein Expression Are Enhanced by Inhibition of the Extracellular Signal-Regulated. Kinase ERK Constantin D, Nosi V, Kehrer N, Vacchini A, Chancellor A, Contassot E, Beshirova A, Prota G, Navarini A, Mori L, De Libero G. Cancer Immunol Res. 2024 Oct 1;12(10):1452-1467. doi:10.1158/2326-6066.CIR-24-0110. https://aacrjournals.org/cancerimmunolres/article/12/10/1452/748716/MR1-Gene-and-Protein-Expression-Are-Enhanced-by | |
| IL-1β Promotes Adipogenesis by Directly Targeting Adipocyte Precursors. Hofwimmer K, de Paula Souza J, Subramanian N, Vujičić M, Rachid L, Méreau H, Zhao C, Dror E, Barreby E, Björkström N K, Wernstedt Asterholm I, Böni-Schnetzler M, Meier D T, Donath M Y, Laurencikiene J. Nat Commun. 2024 Sep 11;15(1):7957. doi: 10.1038/s41467-024-51938-x. https://www.nature.com/articles/s41467-024-51938-x | |
| Targeting Cytokine Networks in Neuroinflammatory Diseases. Becher B, Derfuss T, Liblau R. Nat Rev Drug Discov. 2024 Nov;23(11):862-879. doi: 10.1038/s41573-024-01026-y. Epub 2024 Sep 11. https://www.nature.com/articles/s41573-024-01026-y | |
Neutrophil Extracellular Traps Affect Human Inner Ear Vascular Permeability. Sekulic M, Giaglis S, Chatelain N, Bodmer D, Petkovic V. Int J Mol Sci. 2024 Sep 10;25(18):9766. doi: 10.3390/i. https://www.mdpi.com/1422-0067/25/18/9766 | |
| Circovirus hepatitis in an immunocompromised patient, Switzerland. Hamelin B, Pérot P, Pichler I, Haslbauer JD, Hardy D, Hing D, Louliz S, Regnault B, Pieters A, Heijnen I, Berkemeier C, Mancuso M, Kufner V, Willi N, Jamet A, Dheilly N, Eloit M, Recher M, Huber M, Mertz KD. Emerg Infect Dis. 2024 Oct. doi: 10.3201/eid3010.240678. Online ahead of print. https://wwwnc.cdc.gov/eid/article/30/10/24-0678_article | |
| Circovirus hepatitis in an immunocompromised patient, Switzerland. Hamelin B, Pérot P, Pichler I, Haslbauer JD, Hardy D, Hing D, Louliz S, Regnault B, Pieters A, Heijnen I, Berkemeier C, Mancuso M, Kufner V, Willi N, Jamet A, Dheilly N, Eloit M, Recher M, Huber M, Mertz KD. Emerg Infect Dis. 2024 Oct. doi: 10.3201/eid3010.240678. Online ahead of print. https://wwwnc.cdc.gov/eid/article/30/10/24-0678_article | |
Calorie restriction and rapamycin distinctly restore non-canonical ORF translation in the muscles of aging mice. Mittal N, Ataman A, Tintignac L, Ham DJ, Jörin L, Schmidt A, Sinnreich M, Rueg MA, Zavolan M. NPJ Regen Med. 2024 Sep 19;9(1):23.doi: 10.1038/s41536-024-00369-9. https://www.nature.com/articles/s41536-024-00369-9 | |
| The second international consensus guidelines on the management of BK polyomavirus in kidney transplantation. Kotton CN, Kamar N, Wojciechowski D, Eder M, Hopfer H, Randhawa P, Sester M, Comoli P, Tedesco Silva H, Knoll G, Brennan DC, Trofe-Clark J, Pape L, Axelrod D, Kiberd B, Wong G, Hirsch HH. Transplantation. 2024 Sept 108(9):p 1834-1866 doi: 10.1097/TP.0000000000004976. https://journals.lww.com/transplantjournal/fulltext/2024/09000/the_second_international_consensus_guidelines_on.7.aspx | |
| T cell receptor architecture and clonal tiding provide insight into the transformation trajectory of peripheral T cell lymphomas. Willscher E, Schultheiß C, Paschold L, Schümann FL, Schmidt-Barbo P, Thiele B, Bauer M, Wickenhauser C, Weber T, Binder M. Haematologica. 2024 Aug 29. doi: 10.3324/haematol.2024.285395. Online ahead of print. https://haematologica.org/article/view/haematol.2024.285395 | |
| Stem cell memory EBV-specific T cells control EBV tumor growth and persist in vivo. Palianina D, Mietz J, Stühler C, Arnold B, Bantug G, Münz C, Chijioke O, Khanna N. Sci Adv. 2024 Aug 23;10(34):eado2048. doi: 10.1126/sciadv.ado2048. Epub 2024 Aug 23. https://www.science.org/doi/full/10.1126/sciadv.ado2048 | |
| Semaphorin 3A promotes the long-term persistence of human SVF-derived microvascular networks in engineered grafts. Schwager JM, Di Maggio N, Grosso A, Rasadurai A, Minder N, Hubbell JA, Kappos EA, Schaefer DJ, Briquez PS, Banfi A and Burger MG Front. Bioeng. Biotechnol. 12: 1396450 (2024)doi: 10.3389/fbioe.2024.1396450. https://www.frontiersin.org/journals/bioengineering-and-biotechnology/articles/10.3389/fbioe.2024.1396450/full | |
| A20 haploinsufficiency disturbs immune homeostasis and drives the transformation of lymphocytes with permissive antigen receptors. Schultheiß C, Paschold L, Mohebiany AN, Escher M, Kattimani YM, Müller M, Schmidt-Barbo P, Mensa-Vilaró A, Aróstegui JI, Boursier G, de Moreuil C, Hautala T, Willscher E, Jonas H, Chinchuluun N, Grosser B, Märkl B, Klapper W, Oommen PT, Gössling K, Hoffmann K, Tiegs G, Czernilofsky F, Dietrich S, Freeman A, Schwartz DM, Waisman A, Aksentijevich I, Binder M. Sci Adv. 2024 Aug 23;10(34):eadl3975. doi: 10.1126/sciadv.adl3975. Epub 2024 Aug 21. https://www.science.org/doi/full/10.1126/sciadv.adl3975?rfr_dat=cr_pub++0pubmed&url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org | |
| Polygenic susceptibility for multiple sclerosis is associated with working memory in low-performing young adults. Petrovska J, Coynel D, Freytag V, de Quervain D J-F, Papassotiropoulos A. J Neurol Sci. 2024 Jul 15:463:123138. doi: 10.1016/j.jns.2024.123138. Online ahead of print. https://www.sciencedirect.com/science/article/pii/S0022510X24002739?via%3Dihub | |
| Engineered autologous nasal cartilage for repair of nasal septal perforations - a case series. Kaiser B, Miot S, Wixmerten A, Pullig O, Eyrich M, Fulco I, Vavrina J, Schaefer DJ, Martin I, Barbero A, Haug M. Int J Surg. 2024 Aug 5. doi: 10.1097/JS9.0000000000001843. Online ahead of print. https://journals.lww.com/international-journal-of-surgery/abstract/9900/engineered_autologous_nasal_cartilage_for_repair.1870.aspx | |
| B cells expressing mutated IGHV1-69-encoded antigen receptors related to virus neutralization show lymphoma-like transcriptomes in patients with chronic HCV infection. Schultheiß C, Willscher E, Paschold L, Ackermann C, Escher M, Scholz R, Knapp M, Lützkendorf J, Müller LP, Schulze Zur Wiesch J, Binder M. Hepatol Commun. 2024 Jul 31;8(8):e0503. doi: 10.1097/HC9.0000000000000503. eCollection 2024 Aug 1. https://journals.lww.com/hepcomm/fulltext/2024/08010/b_cells_expressing_mutated_ighv1_69_encoded.19.aspx | |
| Factor H-related protein 1 in systemic lupus erythematosus. Kleer JS, Klehr J, Dubler D, Infanti L, Chizzolini C, Huynh-Do U, Ribi C, Trendelenburg M. Front Immunol. 2024 Jul 29:15:1447991. doi: 10.3389/fimmu.2024.1447991. eCollection 2024. https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2024.1447991/full | |
| Monoallelic de novo AJAP1 loss-of-function variants disrupt trans-synaptic control of neurotransmitter release. Früh S, Boudkkazi S, Koppensteiner P, Sereikaite V, Chen L-Y, Fernandez- Fernandez D, Rem P D, Ulrich D, Schwenk J, Chen Z, Le Monnier E, Fritzius T, Innocenti S M, Besseyrias V, Trovò L, Stawarski M, Argilli E, Sherr E H, van Bon B, Kamsteeg E-J, Iascone M, Pilotta A, Cutrì M R, Azamian M S, Hernández-García H, Lalani S R, Rosenfeld J A, Zhao X, Vogel T P, Ona H, Scott A D, Scheiffele P, Strømgaard K, Tafti M, Gassmann M, Fakler B,Shigemoto R, Bettler B. Sci Adv. 2024 Jul 12;10(28):eadk5462. doi: 10.1126/sciadv.adk5462. Epub 2024 Jul 10. https://www.science.org/doi/10.1126/sciadv.adk5462 | |
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| Human blood-labyrinth barrier on a chip: a unique in vitro tool for investigation of BLB properties. Sekulic M, Abdollahi N, Graf L, Deigendesch N, Puche R, Bodmerab D, Petkovic V. RSC Adv. 2023 Aug 25;13(36):25508-25517. doi: 10.1039/d3ra04704k. eCollection 2023 Aug 21. https://pubs.rsc.org/en/content/articlelanding/2023/RA/D3RA04704K | |
| mTORC2 regulates auditory hair cell structure and function. Cortada M, Levano S, Hall MN 2, Bodmer D. iScience. 2023 Aug 19;26(9):107687. doi: 10.1016/j.isci.2023.107687. eCollection 2023 Sep 15. https://www.sciencedirect.com/science/article/pii/S2589004223017649?via%3Dihub | |
| Exogenous humanin and MOTS-c function as protective agents against gentamicin-induced hair cell damage. Waldmann D, Lu Y, Cortada M, Bodmer D, Huaman SL. Biochem Biophys Res Commun. 2023 Oct 20:678:115-121. doi: 10.1016/j.bbrc.2023.08.033. Epub 2023 Aug 17. https://www.sciencedirect.com/science/article/pii/S0006291X23009798?via%3Dihub | |
| Characterization of engraftment dynamics in myelofibrosis after allogeneic hematopoietic cell transplantation including novel conditioning schemes. Jungius S, Adam FC, Grosheintz K, Medinger M, Buser A, Passweg JR, Halter JP, Meyer SC. Front Oncol. 2023 Aug 10:13:1205387. doi: 10.3389/fonc.2023.1205387. eCollection 2023. https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2023.1205387/full | |
| Urine CXCL10 to Assess BK Polyomavirus Replication After Kidney Transplantation. Haller J, Diebold M, Leuzinger K, Wehmeier C, Handschin J, Amico P, Hirt-Minkowski P, Steiger J, Dickenmann M, Hirsch HH, Schaub S. Transplantation. 2023 Dec 1;107(12):2568-2574. doi: 10.1097/TP.0000000000004712. Epub 2023 Jul 6. https://journals.lww.com/transplantjournal/fulltext/2023/12000/urine_cxcl10_to_assess_bk_polyomavirus_replication.27.aspx | |
Regulator of G-protein signaling 1 critically supports CD8+TRM cell-mediated intestinal immunity. von Werdt D, Gungor B, Barreto de Albuquerque J, Gruber T, Zysset D, Kwong Chung CKC, Corrêa-Ferreira A, Berchtold R, Page N, Schenk M, Kehrl JH, Merkler D, Imhof BA, Stein JV, Abe J, Turchinovich G, Finke D, Hayday AC, Corazza N, Mueller C. Front Immunol. 2023 Apr 20:14:1085895. doi: 10.3389/fimmu.2023.1085895. eCollection 2023. https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2023.1085895/full | |
| Targeting the Siglec–sialic acid axis promotes antitumor immune responses in preclinical models of glioblastoma. P Schmassmann, J Roux, A Buck, N Tatari, S Hogan, J Wang, N R Mantuano, R Wieboldt, S Lee, B Snijder, D Kaymak, T A Martins, M F Ritz, T Shekarian, M Mcdaid, M Weller, T Weiss, H Läubli, G Hutter. DOI: 10.1126/scitranslmed.adf5302. https://www.science.org/doi/10.1126/scitranslmed.adf5302 | |
| Human epidermis organotypic cultures, a reproducible system recapitulating the epidermis in vitro. Experimental Dermatology. Rishika Agarwal, Tanja Dittmar, Hans-Dietmar Beer, Michael Kunz, Simon Müller, Elisabeth A. Kappos, Emmanuel Contassot, Alexander A. Navarini (2023). 2023;00:1-13. doi:10.1111/exd.14823 https://onlinelibrary.wiley.com/doi/full/10.1111/exd.14823 | |
| Iron is a modifier of the phenotypes of JAK2-mutant myeloproliferative neoplasms. Stetka J, Usart M,Kubovcakova L,Rai S, Nageswara Rao T, Sutter J, Hao-Shen H,Dirnhofer S, Geier F, Bader M, Passweg J, Manolova V, Dürrenberger F, Ahmed N, Schroeder T, Ganz T, Nemeth E, Silvestri L, Nai A, Camaschella C and Skoda R. Blood. 2023 Apr 27;141(17):2127-2140. doi: 10.1182/blood.2022017976. 27.04.23 https://pubmed.ncbi.nlm.nih.gov/36758212/ | |
| N-acetylcysteine overcomes NF1 loss-driven resistance to PI3Kα inhibition in breast cancer. Auf der Maur P, Trefny MP, Baumann Z, Vulin M, Correia AL, Diepenbruck M, Kramer N, Volkmann K, Preca BT, Ramos P, Leroy C, Eichlisberger T, Buczak K, Zilli F, Okamoto R, Rad R, Jensen MR, Fritsch C, Zippelius A, Stadler MB, Bentires-Alj M. Cell Rep Med. 2023 Apr 18;4(4):101002. doi: 10.1016/j.xcrm.2023.101002. Epub 2023 Apr 11. PMID: 37044095 18.04.23 https://pubmed.ncbi.nlm.nih.gov/37044095/ | |
| DNA methylation landscapes of prostate cancer brain metastasis are shaped by early driver genetic alterations. Gallon J, Rodriguez-Calero A, Benjak A, Akhoundova D, Maletti S, Amstutz U, Hewer E, Genitsch V, Fleischmann A, Rushing EJ, Grobholz R, Fischer I, Jochum W, Cathomas G, Osunkoya AO, Bubendorf L, Moch H, Thalmann G, Feng FY, Gillessen S, Ng CKY, Rubin MA, Piscuoglio S. Cancer Res. 2023 Apr 14;83(8):1203-1213. doi: 10.1158/0008-5472.CAN-22-2236. 14.04.23 https://pubmed.ncbi.nlm.nih.gov/36749655/ | |
| Pharmacokinetics and Pharmacodynamics of Oral Psilocybin Administration in Healthy Participants. Holze F, Becker AM, Kolaczynska KE, Duthaler U and Liechti ME. Clin Pharmacol Ther. 2023 Apr;113(4):822-831. doi: 10.1002/cpt.2821. Epub 2022 Dec 31. 01.04.23 https://pubmed.ncbi.nlm.nih.gov/36507738/ | |
| AXL expression on homeostatic resident liver macrophages is reduced in cirrhosis following GAS6 production by hepatic stellate cells. Holze F, Becker AM, Kolaczynska KE, Duthaler U and Liechti ME. Cell Mol Gastroenterol Hepatol. 2023 Mar 31;S2352-345X(23)00047-4. doi: 10.1016/j.jcmgh.2023. 03.007. Online ahead of print. 31.03.23 https://www.sciencedirect.com/science/article/pii/S2352345X23000474?via%3Dihub | |
| Autoimmunity and immunodeficiency associated with monoallelic LIG4 mutations via haploinsufficiency. Jauch A, Bignucolo O, Seki S, Ghraichy M, Delmonte O, von Niederhäusern V, Higgins R, Ghosh A, Nishizawa M, Tanaka M, Baldrich A, Köppen J, Hirsiger J, Hupfer R, Ehl S, Rensing-Ehl A, Hopfer H, Savic Prince S, Daley S, Marquardsen F, Meyer B, Tamm M, Daikeler T, Diesch T, Kühne T, Helbling A, Berkemeier C, Heijnen I, Navarini A, Trück J, de Villartay J.-P., Oxenius A, Berger Ch, Hess Ch, D Notarangelo L, Yamamoto H, Recher M. Allergy Clin Immunol. 2023 Mar 31;S0091-6749(23)00422-0. doi: 10.1016/j.jaci.2023.03.022. Online ahead of print. 31.03.23 https://pubmed.ncbi.nlm.nih.gov/37004747/ | |
| VEGF dose controls the coupling of angiogenesis and osteogenesis in engineered bone. Grosso A, Lunger A, Burger MG, Briquez PS, Mai F, Hubbell JA, Schaefer DJ, Banfi A, Di Maggio N. NPJ Regen Med. 2023 Mar 13;8(1):15. doi: 10.1038/s41536-023-00288-1. 13.03.23 https://pubmed.ncbi.nlm.nih.gov/36914692/ | |
| Lung versus gut exposure to air pollution particles differentially affect metabolic health in mice. Bosch AJT, Rohm TV, AlAsfoor S, Low AJY, Keller L, Baumann Z, Parayil N, Stawiski M, Rachid L, Dervos T, Mitrovic S, Meier DT, Cavelti-Weder C. Part Fibre Toxicol. 2023 Mar 9;20(1):7. doi: 10.1186/s12989-023-00518-w. 09.03.23 https://pubmed.ncbi.nlm.nih.gov/36895000/ | |
| Good Manufacturing Practice-compliant change of raw material in the manufacturing process of a clinically used advanced therapy medicinal product-a comparability study. Wixmerten A, Miot S, Bittorf P, Wolf F, Feliciano S, Hackenberg S, Häusner S, Krenger W, Haug M, Martin I, Pullig O, Barbero A. Cytotherapy. 2023 May;25(5):548-558. doi: 10.1016/j.jcyt.2023.01.003. Epub 2023 Mar 7. PMID: 36894437. 07.03.23 https://pubmed.ncbi.nlm.nih.gov/36894437/ | |
| Quantitative proteomic analysis of skeletal muscles from wild-type and transgenic mice carrying recessive Ryr1 mutations linked to congenital myopathies. Eckhardt J, Ruiz A, Koenig S, Frieden M, Meier H, Schmidt A, Treves S, Zorzato F. Elife. 2023 Mar 2;12:e83618. doi: 10.7554/eLife.83618. 02.03.23 https://pubmed.ncbi.nlm.nih.gov/36862731/ | |
| T-cadherin is a novel regulator of pericyte function during angiogenesis. Dasen B, Pigeot S, Born GM, Verrier S, Rivero O, Dittrich PS, Martin I, Filippova M. Am J Physiol Cell Physiol, Feb 20, Online, ahead of print (2023). doi: 10.1152/ajpcell.00326.2022. PMID: 36802732. 20.02.23 https://pubmed.ncbi.nlm.nih.gov/36802732/ | |
| Doublecortin and Glypican-2 concentrations in the cerebrospinal fluid from infants are developmentally downregulated. Brégère C, Fisch U, Halbeisen FS, Schneider C, Dittmar T, Stricker S, Aghlmandi S, Guzman R. PLoS One. 2023 Feb 17;18(2):e0279343. doi: 10.1371/journal.pone.0279343. eCollection 2023. 17.02.23 https://pubmed.ncbi.nlm.nih.gov/36800341/ | |
| Dynamics of antibody titers to SARS-CoV-2 and clinical outcomes after sotrovimab pre-exposure prophylaxis early after allogeneic hematopoietic stem cell transplantation. Capoferri G, Walti CS, Urwyler P, Ragozzino S, Passweg JR, Halter J, Battegay M, Baettig V, Weisser M, Arnold B, Morin B, Guetlin Y, Torres DA, Barut GT, Thiel V, Egli A, Drexler B, Khanna N. Bone Marrow Transplant. 2023 Feb 16;1-3. doi: 10.1038/s41409-023-01936-2. Online ahead of print. 16.02.23 https://pubmed.ncbi.nlm.nih.gov/36797421/ | |
| Impact of nucleic acid extraction procedures on human papillomavirus (HPV) detection and genotyping. Naegele K, Weissbach FH, Leuzinger K, Gosert R, Bubendorf L, Hirsch HH. J Med Virol. 2023 Feb;95(2):e28583. doi: 10.1002/jmv.28583.PMID: 36794677. 16.02.23 https://pubmed.ncbi.nlm.nih.gov/36794677/ | |
| The alarmin interleukin-33 promotes the expansion and preserves the stemness of Tcf-1+ CD8+ T cells in chronic viral infection. AF Marx, Kallert SM, Brunner TM, Villega JA, Geier F, Fixemer J, Abreu-Mota T, Reuther P, Bonilla WV, Fadejeva J, Kreutzfeldt M, Wagner I, Aparicio-Domingo P, Scarpellino L, Charmoy M, Utzschneider DT, Hagedorn C, Lu M, Cornille K, Stauffer K, Kreppel F, Merkler D, Zehn D, Held W, Luther SA, Löhning M, D Pinschewer DD. Immunity. 2023 Feb 14;S1074-7613(23)00041-9. doi: 10.1016/j.immuni.2023.01.029. Online ahead of print. 14.02.23 https://pubmed.ncbi.nlm.nih.gov/36809763/ | |
| Ketanserin Reverses the Acute Response to LSD in a Randomized, Double-Blind, Placebo-Controlled, Crossover Study in Healthy Participants. Becker AM, Klaiber A, Holze F, Istampoulouoglou I, Duthaler U, Varghese N, Eckert A, Liechti ME. Int J Neuropsychopharmacol. 2023 Feb 14;26(2):97-106. doi: 10.1093/ijnp/pyac075. 14.02.23 https://pubmed.ncbi.nlm.nih.gov/36342343/ | |
| Human 3D nucleus pulposus microtissue model to evaluate the potential of pre-conditioned nasal chondrocytes for the repair of degenerated intervertebral disc. Kasamkattil J, Gryadunova A, Schmid R, Gay-Dujak MHP, Dasen B, Hilpert M, Pelttari K, Martin I, Schären S, Barbero A, Krupkova O, Mehrkens A. " Front Bioeng Biotechnol. 2023 Feb 14;11:1119009. doi: 10.3389/fbioe.2023.1119009. eCollection 2023. ". 14.02.23 https://pubmed.ncbi.nlm.nih.gov/36865027/ | |
| MRGPRX2: A novel biomarker in mastocytosis? Konantz M, Merkel T, Meyer SC, Hartmann K. J Allergy Clin Immunol Pract. 2023 Feb;11(2):669-671. doi: 10.1016/j.jaip.2022.10.053. PMID: 36759088. 11.02.23 https://pubmed.ncbi.nlm.nih.gov/36759088/ | |
| Serum Glial Fibrillary Acidic Protein Compared With Neurofilament Light Chain as a Biomarker for Disease Progression in Multiple Sclerosis. Meier S, Willemse EAJ, Schaedelin S, Oechtering J, Lorscheider J, Melie-Garcia L, Cagol A, Barakovic M, Galbusera R, Subramaniam S, Barro C, Abdelhak A, Thebault S, Achtnichts L, Lalive P, Müller S, Pot C, Salmen A, Disanto G, Zecca C, D'Souza M, Orleth A, Khalil M, Buchmann A, Du Pasquier R, Yaldizli Ö, Derfuss T, Berger K, Hermesdorf M, Wiendl H, Piehl F, Battaglini M, Fischer U, Kappos L, Gobbi C, Granziera C, Bridel C, Leppert D, Maceski AM, Benkert P, Kuhle J. JAMA Neurol. 2023 Feb 6;80(3):287-297. doi: 10.1001/jamaneurol.2022.5250. Online ahead of print. 06.02.23 https://pubmed.ncbi.nlm.nih.gov/36745446/ | |
| The NFIA-ETO2 fusion blocks erythroid maturation and induces pure erythroid leukemia in cooperation with mutant TP53. Piqué-Borràs MR, Jevtic Z, Otzen Bagger F, Seguin J, Sivalingam R, Bezerra MF, Louwaige A, Juge S, Nellas I, Ivanek R, Tzankov A, Moll U, Cantillo OV, Schulz-Heddergott R, Fagnan A, Mercher T, Schwaller J. Blood. 2023 Feb 3:blood.2022017273. doi: 10.1182/blood.2022017273. Online ahead of print. 03.02.23 https://www.sciencedirect.com/science/article/pii/S0006497123003105?via%3Dihub | |
| Deletion of SNX9 alleviates CD8 T cell exhaustion for effective cellular cancer immunotherapy. Marcel P. Trefny, Nicole Kirchhammer, Priska Auf der Maur, Marina Natoli, Dominic Schmid, Markus Germann, Laura Fernandez Rodriguez, Petra Herzig, Jonas Lötscher, Maryam Akrami, Jane C. Stinchcombe, Michal A. Stanczak, Andreas Zingg, Melanie Buchi, Julien Roux, Romina Marone, Leyla Don, Didier Lardinois, Mark Wiese, Lukas T. Jeker, Mohamed Bentires-Alj, Jérémie Rossy, Daniela S. Thommen, Gillian M. Griffiths, Heinz Läubli, Christoph Hess, Alfred Zippelius. Nat Commun 14, 86 (2023). https://doi.org/10.1038/s41467-022-35583-w. 02.02.23 https://www.nature.com/articles/s41467-022-35583-w | |
| A patient-centric modeling framework captures recovery from SARS-CoV-2 infection. Ruffieux H, Hanson AL, Lodge S, Lawler NG, Whiley L, Gray N, Nolan TH, Bergamaschi L, Mescia F, Turner L, de Sa A, Pelly VS, The Cambridge Institute of Therapeutic Immunology and Infectious Disease-National Institute of Health Research (CITIID-NIHR) BioResource COVID-19 Collaboration*, Kotagiri P, Kingston N, Bradley JR, Holmes E, Wist J, Nicholson JK, Lyons PA, Smith KGC, Richardson S, Bantug GR & Hess C. Nat Immunol. 2023 Feb;24(2):349-358. doi: 10.1038/s41590-022-01380-2. Epub 2023 Jan 30. 30.01.23 https://pubmed.ncbi.nlm.nih.gov/36717723/ | |
| Soluble amyloid-β precursor peptide does not regulate GABAB receptor activity. Rem PD, Sereikaite V, Fernández-Fernández D, Reinartz S, Ulrich D, Fritzius T, Trovo L, Roux S, Chen Z, Rondard P, Pin JP, Schwenk J, Fakler B, Gassmann M, Rinaldi Barkat T, Strømgaard K, Bettler B. Elife. 2023 Jan 23;12:e82082. doi: 10.7554/eLife.82082. 23.01.23 https://pubmed.ncbi.nlm.nih.gov/36688536/ | |
| Classic psychedelics do not affect T cell and monocyte immune responses. Rudin D, Areesanan A, Liechti ME and Gründemann C. Front Psychiatry. 2023 Jan 20;14:1042440. doi: 10.3389/fpsyt.2023.1042440. eCollection 2023. 20.01.23 https://pubmed.ncbi.nlm.nih.gov/36741125/ | |
| Investigation of morpholine isosters for the development of a potent, selective and metabolically stable mTOR kinase inhibitor. De Pascale M, Bissegger L, Tarantelli C, Beaufils F, Prescimone A, Hedad HMS, Kayali O, Orbegozo C, Raguž L, Schaefer T, Hebeisen P, Bertoni F, Wymann MP, Borsari C. European Journal of Medicinal Chemistry. Volume 248, 15 February 2023, 115038, doi: 10.1016/j.ejmech.2022.115038. 28.12.22 | |
| Engineering of immunoinstructive extracellular matrices for enhanced osteoinductivity. Garcia-Garcia A, Pigeot S, Martin I. Bioactive Materials, 24: 174-184 (2023). doi: 10.1016/j.bioactmat.2022.12.017. PMID: 36606254. 21.12.22 https://pubmed.ncbi.nlm.nih.gov/36606254/ | |
| Liraglutide Lowers Endothelial Vascular Cell Adhesion Molecule-1 in Murine Atherosclerosis Independent of Glucose Levels. Punjabi M, Kosareva A, Xu L, Ochoa-Espinosa A, Decembrini S, Hofmann G, Wyttenbach S, Rolin B, Nyberg M, Kaufmann BA. JACC Basic Transl Sci. 2022 Dec 7;8(2):189-200. doi: 10.1016/j.jacbts.2022.08.002. eCollection 2023 Feb. 07.12.23 https://www.sciencedirect.com/science/article/pii/S2452302X22003023 | |
| BK Polyomavirus Consensus. Hirsch HH, Mengel M, Kamar N. Clinical Infectious Diseases. Clin Infect Dis. 2022 Nov 30;75(11):2046-2047. doi: 10.1093/cid/ciac594. 30.11.22 https://pubmed.ncbi.nlm.nih.gov/35856634/ | |
| Mini- and macro-scale direct perfusion bioreactors with optimized flow for engineering 3D tissues. Born G, Plantier E, Nannini G, Caimi A, Mazzoleni A, Asnaghi MA, Muraro MG, Scherberich A, Martin I, García-García A. Biotechnol. Feb;18(2): e2200405. doi: 10.1002/biot.202200405. Epub Feb 2023. doi: 10.1002/biot.202200405. PMID 36428229. 25.11.22 https://pubmed.ncbi.nlm.nih.gov/36428229/ | |
| Defective Desmosomal Adhesion Causes Arrhythmogenic Cardiomyopathy by Involving an Integrin-αVβ6/TGF-β Signaling Cascade. Schinner C, Xu L, Franz H, Zimmermann A, Wanuske MT, Rathod M, Hanns P, Geier F, Pelczar P, Liang Y, Lorenz V, Stüdle C, Maly PI, Kauferstein S, Beckmann BM, Sheikh F, Kuster GM, Spindler V. Circulation. Circulation. 2022 Nov 22;146(21):1610-1626. doi: 10.1161/CIRCULATIONAHA.121.057329. 22.11.22 https://pubmed.ncbi.nlm.nih.gov/36268721/ | |
| Molecular Characterization of BK Polyomavirus Replication in Allogeneic Hematopoietic Cell Transplantation. Leuzinger K, Kaur A, Wilhelm M, Frank K, Hillenbrand CA, Weissbach FH, Hirsch HH. The Journal of Infectious Diseases. J Infect Dis. 2022 Nov 21;jiac450. doi: 10.1093/infdis/jiac450. Online ahead of print. 21.11.22 https://pubmed.ncbi.nlm.nih.gov/36409589/ | |
| Deciphering molecular and cellular ex vivo responses to bispecific antibodies PD1-TIM3 and PD1-LAG3 in human tumors. Natoli M, Hatje K, Gulati P, Junker F, Herzig P, Jiang Z, Davydov II, Germann M, Trüb M, Marbach D, Zwick A, Weber P, Seeber S, Wiese M, Lardinois D, Heinzelmann-Schwarz V, Rosenberg R, Tietze L, Mertz KD, Umaña P, Klein C, Codarri-Deak L, Kao H, Zippelius A. Journal for Immunotherapy of Cancer. J Immunother Cancer. 2022 Nov;10(11):e005548. doi: 10.1136/jitc-2022-005548. 10.11.22 https://pubmed.ncbi.nlm.nih.gov/36319064/ | |
| Severe Neuro-COVID is associated with peripheral immune signatures, autoimmunity and neurodegeneration: a prospective cross-sectional study. Etter MM, Martins TA, Kulsvehagen L, Pössnecker E, Duchemin W, Hogan S, Sanabria-Diaz G, Müller J, Chiappini A, Rychen J, Eberhard N, Guzman R, Mariani L, Melie-Garcia L, Keller E, Jelcic I, Pargger H, Siegemund M, Kuhle J, Oechtering J, Eich C, Tzankov A, Matter MS, Uzun S, Yaldizli Ö, Lieb JM, Psychogios MN, Leuzinger K, Hirsch HH, Granziera C, Pröbstel AK, Hutter G. Nature Communications. Nat Commun. 2022 Nov 9;13(1):6777. doi: 10.1038/s41467-022-34068-0. 09.11.22 https://pubmed.ncbi.nlm.nih.gov/36351919/ | |
| Review: Combination cancer immunotherapies: Emerging treatment strategies adapted to the tumor microenvironment. Kirchhammer N, Trefny MP, Auf der Maur P, Läubli H, Zippelius A. Science Translational Medicine. Sci Transl Med. 2022 Nov 9;14(670):eabo3605. doi: 10.1126/scitranslmed.abo3605. Epub 2022 Nov 9. 09.11.22 https://pubmed.ncbi.nlm.nih.gov/36350989/ | |
| Targeting cancer glycosylation repolarizes tumor-associated macrophages allowing effective immune checkpoint blockade. Stanczak MA, Mantuano NR, Kirchhammer N, Sanin DE, Jacob F, Coelho R, Everest-Dass AV, Wang J, Trefny MP, Monaco G, Bärenwaldt A, Gray MA, Petrone A, Kashyap AS, Glatz K, Kasenda B, Normington K, Broderick J, Peng L, Pearce OMT, Pearce EL, Bertozzi CR, Zippelius A, Läubli H. Science Translational Medicine. Transl Med. 2022 Nov 2;14(669):eabj1270. doi: 10.1126/scitranslmed.abj1270. Epub 2022 Nov 2. 02.11.22 https://pubmed.ncbi.nlm.nih.gov/36322632/ | |
| «Overlapping gene dependencies for PARP inhibitors and carboplatin response identified by functional CRISPR-Cas9 screening in ovarian cancer». Coelho R, Tozzi A, Disler M, Lombardo F, Fedier A, López MN, Freuler F, Jacob F, Heinzelmann-Schwarz V. Cell, Death and Disease. Death Dis. 2022 Oct 28;13(10):909. doi: 10.1038/s41419-022-05347-x. 28.10.22 https://pubmed.ncbi.nlm.nih.gov/36307400/ | |
| Forced expression of the non-coding RNA miR-17~92 restores activation and function in CD28-deficient CD4+ T cells. Dölz M, Hasiuk M, Gagnon JD, Kornete M, Marone R, Bantug G, Kageyama R, Hess C, Ansel KM, Seyres D, Roux J, T Jeker LT. iScience. Science. 2022 Oct 17;25(11):105372. doi: 10.1016/j.isci.2022.105372. eCollection 2022 Nov 18. 17.10.22 https://pubmed.ncbi.nlm.nih.gov/36388982/ | |
| Stereospecific Synthesis of Substituted Sulfamidates as Privileged Morpholine Building Blocks. Stojiljkovic, U., Meyer, C., Boulay, P., Hebeisen, P., Rageot, D., Wymann, M., Borsari, C. Synthesis. Synthesis 2022, Doi: 10.1055/a-1915-7794. 10.10.22 http://dx.doi.org/10.1055/a-1915-7794 | |
| Comment: Two-drug trick to target the brain blocks toxicity in the body. Wymann MP, Borsari C. Nature. Comment Nature. 2022 Sep;609(7928):681-683. doi: 10.1038/d41586-022-02892-5. 14.09.22 https://www.nature.com/articles/d41586-022-02892-5 | |
| Receptor clustering and pathogenic complement activation in myasthenia gravis depend on synergy between antibodies with multiple subunit specificities. Rose N, Holdermann S, Callegari I, Kim H, Fruh I, Kappos L, Kuhle J, Müller M, Sanderson NSR, Derfuss T. Acta Neuropathologica. Acta Neuropathol. 2022 Nov;144(5):1005-1025. 08.09.22 https://pubmed.ncbi.nlm.nih.gov/36074148/ | |
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| Nose to Spine: spheroids generated by human nasal chondrocytes for scaffold-free nucleus pulposus augmentation. Gryadunova A, Kasamkattil J, Gay MHP, Dasen B, Pelttari K, Mironov V, Martin I, Schären S, Barbero A, Krupkova O, Mehrkens A. Acta Biomater. 134: 240-251 (2021). https://www.sciencedirect.com/science/article/pii/S174270612100502X?via%3Dihub | |
| The Genomic Landscape of Serrated Lesion of the Colorectum: Similarities and Differences With Tubular and Tubulovillous Adenomas. Tornillo L, Lehmann FS, Garofoli A, Paradiso V, Ng CKY, Piscuoglio S. Front Oncol. 2021 Oct 12;11:668466. https://www.frontiersin.org/articles/10.3389/fonc.2021.668466/full | |
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| Engineering of fully humanized and vascularized 3D bone marrow niches sustaining undifferentiated human cord blood hematopoietic stem and progenitor cells. Born G, Nikolova M, Scherberich A, Treutlein B, García-García A, Martin I. J Tissue Eng. 12: 1-11 (2021). https://journals.sagepub.com/doi/10.1177/20417314211044855?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed | |
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| Spatial regulation by multiple Gremlin1 enhancers provides digit development with cis-regulatory robustness and evolutionary plasticity. Malkmus J, Ramos Martins L, Jhanwar S, Kircher B, Palacio V, Sheth R, Leal F, Duchesne A, Lopez-Rios J, Peterson KA, Reinhardt R, Onimaru K, Cohn MJ, Zuniga A, Zeller R. Nature Commun 12, 5557. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455560/ | |
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| Manufacturing of Human Tissues as off-the-Shelf Grafts Programmed to Induce Regeneration. Pigeot S, Klein T, Gullotta F, Dupard SJ, Garcia Garcia A, García-García A, Prithiviraj S, Lorenzo P, Filippi M, Jaquiery C, Kouba L, Asnaghi MA, Raina DB, Dasen B, Isaksson H, Önnerfjord P, Tägil M, Bondanza A, Martin I, Bourgine PE. Adv Mater. 33, 2103737: 1-13 (2021). https://onlinelibrary.wiley.com/doi/10.1002/adma.202103737 | |
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