Publications

Below you can find a recent publication list of the Department of Biomedicine.
If you are looking for publications of a specific group please refer to the corresponding research group.

August 2021 - December 2022

BK Polyomavirus Consensus. Hirsch HH, Mengel M, Kamar N. Clinical Infectious Diseases. Clin Infect Dis. 2022 Nov 30;75(11):2046-2047. doi: 10.1093/cid/ciac594. IF 20.999. 30.11.22
pubmed.ncbi.nlm.nih.gov/35856634/
Defective Desmosomal Adhesion Causes Arrhythmogenic Cardiomyopathy by Involving an Integrin-αVβ6/TGF-β Signaling Cascade. Schinner C, Xu L, Franz H, Zimmermann A, Wanuske MT, Rathod M, Hanns P, Geier F, Pelczar P, Liang Y, Lorenz V, Stüdle C, Maly PI, Kauferstein S, Beckmann BM, Sheikh F, Kuster GM, Spindler V. Circulation. Circulation. 2022 Nov 22;146(21):1610-1626. doi: 10.1161/CIRCULATIONAHA.121.057329. IF 39.918. 22.11.22
pubmed.ncbi.nlm.nih.gov/36268721/
Molecular Characterization of BK Polyomavirus Replication in Allogeneic Hematopoietic Cell Transplantation. Leuzinger K, Kaur A, Wilhelm M, Frank K, Hillenbrand CA, Weissbach FH, Hirsch HH. The Journal of Infectious Diseases. J Infect Dis. 2022 Nov 21;jiac450. doi: 10.1093/infdis/jiac450. Online ahead of print. IF 5.838. 21.11.22
pubmed.ncbi.nlm.nih.gov/36409589/
Deciphering molecular and cellular ex vivo responses to bispecific antibodies PD1-TIM3 and PD1-LAG3 in human tumors. Natoli M, Hatje K, Gulati P, Junker F, Herzig P, Jiang Z, Davydov II, Germann M, Trüb M, Marbach D, Zwick A, Weber P, Seeber S, Wiese M, Lardinois D, Heinzelmann-Schwarz V, Rosenberg R, Tietze L, Mertz KD, Umaña P, Klein C, Codarri-Deak L, Kao H, Zippelius A. Journal for Immunotherapy of Cancer. J Immunother Cancer. 2022 Nov;10(11):e005548. doi: 10.1136/jitc-2022-005548. IF 12.485. 10.11.22
pubmed.ncbi.nlm.nih.gov/36319064/
Severe Neuro-COVID is associated with peripheral immune signatures, autoimmunity and neurodegeneration: a prospective cross-sectional study. Etter MM, Martins TA, Kulsvehagen L, Pössnecker E, D­uchemin W, Hogan S, Sanabria-Diaz G, Müller J, Chiappini A, Rychen J, Eberhard N, Guzman R, Mariani L, Melie-Garcia L, Keller E, Jelcic I, Pargger H, Siegemund M, Kuhle J, Oechtering J, Eich C, Tzankov A, Matter MS, Uzun S, Yaldizli Ö, Lieb JM, Psychogios MN, Leuzinger K, Hirsch HH, Granziera C, Pröbstel AK, Hutter G. Nature Communications. Nat Commun. 2022 Nov 9;13(1):6777. doi: 10.1038/s41467-022-34068-0. IF 17.694. 09.11.22
pubmed.ncbi.nlm.nih.gov/36351919/
Review: Combination cancer immunotherapies: Emerging treatment strategies adapted to the tumor microenvironment. Kirchhammer N, Trefny MP, Auf der Maur P, Läubli H, Zippelius A. Science Translational Medicine. Sci Transl Med. 2022 Nov 9;14(670):eabo3605. doi: 10.1126/scitranslmed.abo3605. Epub 2022 Nov 9. IF 19.343. 09.11.22
pubmed.ncbi.nlm.nih.gov/36350989/
Targeting cancer glycosylation repolarizes tumor-associated macrophages allowing effective immune checkpoint blockade. Stanczak MA, Mantuano NR, Kirchhammer N, Sanin DE, Jacob F, Coelho R, ­Everest-Dass AV, Wang J, Trefny MP, Monaco G, Bärenwaldt A, Gray MA, Petrone A, Kashyap AS, Glatz K, Kasenda B, Normington K, Broderick J, Peng L, Pearce OMT, Pearce EL, Bertozzi CR, Zippelius A, Läubli H. Science Translational Medicine. Transl Med. 2022 Nov 2;14(669):eabj1270. doi: 10.1126/scitranslmed.abj1270. Epub 2022 Nov 2. IF 19.343. 02.11.22
pubmed.ncbi.nlm.nih.gov/36322632/
 «Overlapping gene dependencies for PARP inhibitors and carboplatin response identified by functional CRISPR-Cas9 screening in ovarian cancer». Coelho R, Tozzi A, Disler M, Lombardo F, Fedier A, López MN, Freuler F, Jacob F, Heinzelmann-Schwarz V. Cell, Death and Disease. Death Dis. 2022 Oct 28;13(10):909. doi: 10.1038/s41419-022-05347-x. IF 9.696. 28.10.22
pubmed.ncbi.nlm.nih.gov/36307400/
Forced expression of the non-coding RNA miR-17~92 restores activation and function in CD28-deficient CD4+ T cells. Dölz M, Hasiuk M, Gagnon JD, Kornete M, Marone R, ­Bantug G, Kageyama R, Hess C, Ansel KM, Seyres D, Roux J, T Jeker LT. iScience. Science. 2022 Oct 17;25(11):105372. doi: 10.1016/j.isci.2022.105372. eCollection 2022 Nov 18. IF 6.107. 17.10.22
pubmed.ncbi.nlm.nih.gov/36388982/
Stereospecific Synthesis of Substituted Sulfamidates as Privileged Morpholine Building Blocks. Stojiljkovic, U., Meyer, C., Boulay, P., Hebeisen, P., Rageot, D., Wymann, M., ­Borsari, C. Synthesis. Synthesis 2022, Doi: 10.1055/a-1915-7794. IF 3.019. 10.10.22
dx.doi.org/10.1055/a-1915-7794
Comment: Two-drug trick to target the brain blocks toxicity in the body. Wymann MP, Borsari C. Nature. Comment Nature. 2022 Sep;609(7928):681-683. doi: 10.1038/d41586-022-02892-5. IF 69.504. 14.09.22
www.nature.com/articles/d41586-022-02892-5
Receptor clustering and pathogenic complement activation in myasthenia gravis depend on synergy between antibodies with multiple subunit specificities. Rose N, Holdermann S, Callegari I, Kim H, Fruh I, Kappos L, Kuhle J, Müller M, Sanderson NSR, Derfuss T. Acta Neuropathologica. Acta Neuropathol. 2022 Nov;144(5):1005-1025. IF 15.887. 08.09.22
pubmed.ncbi.nlm.nih.gov/36074148/
Low Baseline but Not Delta Cortisol Relates to 28-Day Transplant-Free Survival in Acute and Acute-on-Chronic Liver Failure. Roth S, Flint E, Ghataore L, Patel VC, Singanayagam A, Vincent RP, Triantafyllou E, Ma Y, Bernal W, Auzinger G, Heneghan M, Antoniades C, Christ-Crain M, McPhail MJW, Taylor DR, Wendon J, Bernsmeier C. Gastro Hep Advances. Gastro Hep Advances. 2022. Vol 2(1). p72-82. Published online: September 03, 2022, DOI:https://doi.org/10.1016/j.gastha.2022.08.006. 05.09.22
pubmed.ncbi.nlm.nih.gov/35857639/
www.sciencedirect.com/science/article/pii/S2772572322001479
Targeted transcript analysis in muscles from patients with genetically diverse congenital myopathies. Bachmann C, Franchini M, Van den Bersselaar LR, Kruijt N, Voermans NC, Bouman K, Kamsteeg EJ, Knop KC, Ruggiero L, Santoro L, Nevo Y, Wilmshurst J, Vissing J, Sinnreich M, Zorzato D, Muntoni F, Jungbluth H, Zorzato F, Treves S. Brain Communications. Brain Communications, Volume 4, Issue 5, 2022, fcac224, doi.org/10.1093/braincomms/fcac224. IF 1.010. 02.09.22
academic.oup.com/braincomms/article/4/5/fcac224/6687656
Small-diameter bacterial cellulose-based vascular grafts for coronary artery bypass grafting in a pig model. Fusco D, Meissner F, Podesser BK, Marsano A, Grapow M, ­Eckstein F, Winkler B. frontiers. Front Cardiovasc Med. 2022 Sep 26;9:881557. doi: 10.3389/fcvm.2022.881557. eCollection 2022. IF 5.848. 26.08.22
pubmed.ncbi.nlm.nih.gov/36225961/
Mycobacterium abscessus pathogenesis identified by phenogenomic analyses. Boeck L, Burbaud S, Skwark M, Pearson WH, Sangen J, Wuest AW, Marshall EKP, Weimann A, Everall I, Bryant JM, Malhotra S, Bannerman BP, Kierdorf K, Blundell TL, Dionne MS, Parkhill J, Andres Floto R. Nature Microbiology. Nat Microbiol. 2022 Sep;7(9):1431-1441. IF 30.964. 25.08.22. 
www.nature.com/articles/s41564-022-01204-x
Review: Siglec receptors as new immune checkpoints in cancer. Stanczak MA, Läubli H. Molecular Aspects of Medicine. Mol Aspects Med. 2022 Aug 7;101112. doi: 10.1016/j.mam.2022.101112. IF 16.337. 07.08.22
pubmed.ncbi.nlm.nih.gov/35948467/
C1q as a target molecule to treat human disease: What do mouse studies teach us? Schulz K, Trendelenburg M. Front Immunol. Front Immunol. 2022 Aug 3;13:958273. doi: 10.3389/fimmu.2022.958273. IF 8.787. 03.08.22
pubmed.ncbi.nlm.nih.gov/35990646/
Anti-C1q autoantibodies from systemic lupus erythematosus patients enhance CD40-CD154-mediated inflammation in peripheral blood mononuclear cells invitro. ­Rabatscher PA, Trendelenburg M. Clinical & Translational Immunology. Clin Transl Immunology. 2022 Aug 2;11(8):e1408. doi: 10.1002/cti2.1408. IF 6.515. 02.08.22
pubmed.ncbi.nlm.nih.gov/35928801/
NK cells with tissue-resident traits shape response to immunotherapy by inducing adaptive antitumor immunity. Kirchhammer N, Trefny MP, Natoli M, Brücher D, Smith SN, ­Werner F, Koch V, Schreiner D, Bartoszek E, Buchi M, Schmid M, Breu D, ­Hartmann KP, Zaytseva P, Thommen DS, Läubli H, Böttcher JP, Stanczak MA, Kashyap AS, Plückthun A, ­Zippelius A. Science Translational Medicine. Sci Transl Med. 2022 Jul 13;14(653):eabm9043. doi: 10.1126/scitranslmed.abm9043. Epub 2022 Jul 13. IF 19.343. 13.07.22
pubmed.ncbi.nlm.nih.gov/35857639/
Safe administration of subsequent mRNA COVID-19 vaccine doses following a possible allergic reaction to the first dose. Roth MS, Chantraine S, Morales Mateluna CA, Hartmann K*, Berger CT* (*equally). The Journal of the European Academy of Dermatology and Venereology. J Eur Acad Dermatol Venereol. 2022 Nov;36(11):e880-e883. doi: 10.1111/jdv.18387. Epub 2022 Jul 12. IF 9.228. 20.06.22
onlinelibrary.wiley.com/doi/10.1111/jdv.18387
Integrative proteogenomic characterization of hepatocellular carcinoma across etiologies and stages. Ng CKY, Dazert E, Boldanova T, Coto-Llerena M, Nuciforo S, Ercan C, Suslov A, Meier MA, Bock T, Schmidt A, Ketterer S, Wang X, Wieland S, Matter MS, Colombi M, Piscuoglio S, Terracciano LM, Hall MN, Heim MH. Nat Commun. 2022 May 4;13(1):2436. IF 14.919
www.nature.com/articles/s41467-022-29960-8
Alterations in homologous recombination repair genes in prostate cancer brain metastases. Rodriguez-Calero A, Gallon J, Akhoundova D, Maletti S, Ferguson A, Cyrta J, Amstutz U, Garofoli A, Paradiso V, Tomlins SA, Hewer E, Genitsch V, Fleischmann A, Vassella E, Rushing EJ, Grobholz R, Fischer I, Jochum W, Cathomas G, Osunkoya AO, Bubendorf L, Moch H, Thalmann G, Ng CKY, Gillessen S, Piscuoglio S, Rubin MA. Nat Commun. 2022 May 3;13(1):2400. IF 14.919
www.nature.com/articles/s41467-022-30003-5.pdf
Targeting colonic macrophages improves glycemic control in high-fat diet-induced obesity. Rohm TV, Keller L, Bosch AJT, AlAsfoor S, Baumann Z, Thomas A, Wiedemann SJ, Steiger L, Dalmas E, Wehner J, Rachid L, Mooser C, Yilmaz B, Fernandez Trigo N, Jauch AJ, Wueest S, Konrad D, Henri S, Niess JH, Hruz P, Ganal-Vonarburg SC, Roux J, Meier DT, Cavelti-Weder C. Commun Biol. 2022 Apr 19;5(1):370. IF 6.268
www.nature.com/articles/s42003-022-03305-z
Identification of TPM2 and CNN1 as Novel Prognostic Markers in Functionally Characterized Human Colon Cancer-Associated Stromal Cells. Mele V, Basso C, Governa V, Glaus Garzon JF, Muraro MG, Däster S, Nebiker CA, Mechera R, Bolli M, Schmidt A, Geiger R, Spagnoli GC, Christoforidis D, Majno PE, Borsig L, Iezzi G. Cancers (Basel). 2022 Apr 16;14(8):2024. IF: 6.639
www.ncbi.nlm.nih.gov/pmc/articles/PMC9025001/
Covalent Proximity Scanning of a Distal Cysteine to Target PI3Kα. Borsari C, Keles E, McPhail JA, Schaefer A, Sriramaratnam R, Goch W, Schaefer T, De Pascale M, Bal W, Gstaiger M, Burke JE, Wymann MP. J Am Chem Soc. 2022 Apr 13;144(14):6326-6342. IF 15.419
pubs.acs.org/doi/10.1021/jacs.1c13568
Serum neurofilament light chain for individual prognostication of disease activity in people with multiple sclerosis: a retrospective modelling and validation study. Benkert P, Meier S, Schaedelin S, Manouchehrinia A, Yaldizli Ö, Maceski A, Oechtering J, Achtnichts L, Conen D, Derfuss T, Lalive PH, Mueller C, Müller S, Naegelin Y, Oksenberg JR, Pot C, Salmen A, Willemse E, Kockum I, Blennow K, Zetterberg H, Gobbi C, Kappos L, Wiendl H, Berger K, Sormani MP, Granziera C, Piehl F, Leppert D, Kuhle J; NfL Reference Database in the Swiss Multiple Sclerosis Cohort Study Group. Lancet Neurol. 2022 Mar;21(3):246-257. IF: 44.182
www.sciencedirect.com/science/article/pii/S1474442222000096
Determinants of SARS-CoV-2 transmission to guide vaccination strategy in an urban area. Brüningk SC, Klatt J, Stange M, Mari A, Brunner M, Roloff TC, Seth-Smith HMB, Schweitzer M, Leuzinger K, Søgaard KK, Albertos Torres D, Gensch A, Schlotterbeck AK, Nickel CH, Ritz N, Heininger U, Bielicki J, Rentsch K, Fuchs S, Bingisser R, Siegemund M, Pargger H, Ciardo D, Dubuis O, Buser A, Tschudin-Sutter S, Battegay M, Schneider-Sliwa R, Borgwardt KM, Hirsch HH, Egli A. Virus Evol. 2022 Mar 17;8(1):veac002. IF 7.98
academic.oup.com/ve/article/8/1/veac002/6549831
Epithelial GPR35 protects from Citrobacter rodentium infection by preserving goblet cells and mucosal barrier integrity. Melhem H, Kaya B, Kaymak T, Wuggenig P, Flint E, Roux J, Oost KC, Cavelti-Weder C, Balmer ML, Walser JC, Morales RA, Riedel CU, Liberali P, Villablanca EJ, Niess JH. Mucosal Immunol. 2022 Mar;15(3):443-458. IF 7.313
www.nature.com/articles/s41385-022-00494-y
T-cadherin Expressing Cells in the Stromal Vascular Fraction of Human Adipose Tissue: Role in Osteogenesis and Angiogenesis. Guerrero J, Dasen B, Frismantiene A, Pigeot S, Ismail T, Schaefer DJ, Philippova M, Resink TJ, Martin I, Scherberich A. Stem Cells Transl Med. 11(2): 213-229 (2022). IF 6.940
academic.oup.com/stcltm/article/11/2/213/6544662
Siglec receptors modulate dendritic cell activation and antigen presentation to T cells in cancer. Wang J, Manni M, Bärenwaldt A, Wieboldt R, Kirchhammer N, Ivanek R, Stanczak M, Zippelius A, König D, Rodrigues Manutano N, Läubli H. Front Cell Dev Biol. 2022 Mar 3;10:828916. IF 6.684
www.frontiersin.org/articles/10.3389/fcell.2022.828916/full
Improvement of muscle strength in a mouse model for congenital myopathy treated with HDAC and DNA methyltransferase inhibitors. Ruiz A, Benucci S, Duthaler U, Bachmann C, Franchini M, Noreen F, Pietrangelo L, Protasi F, Treves S, Zorzato F. eLife. 2022 Mar 3;11:e73718. IF 8.146
elifesciences.org/articles/73718
Engineering of Tracheal Grafts Based on Recellularization of Laser-Engraved Human Airway Cartilage Substrates. Baranovskii D, Demner J, Nürnberger S, Lyundup A, Redl H, Hilpert M, Pigeot S, Krasheninnikov M, Krasilnikova O, Klabukov I, Parshin V, Martin I, Lardinois D, Barbero A. Cartilage. 1-12 (2022). IF 6.634
journals.sagepub.com/doi/10.1177/19476035221075951+
Magnesium sensing via LFA-1 regulates CD8 + T cell effector function. Lötscher J, Martí I Líndez AA, Kirchhammer N, Cribioli E, Giordano Attianese GMP, Trefny MP, Lenz M, Rothschild SI, Strati P, Künzli M, Lotter C, Schenk SH, Dehio P, Löliger J, Litzler L, Schreiner D, Koch V, Page N, Lee D, Grählert J, Kuzmin D, Burgener AV, Merkler D, Pless M, Balmer ML, Reith W, Huwyler J, Irving M,King CG, Zippelius A, Hess C. Cell. 2022 Feb 17;185(4):585-602. e29. IF: 41.584
www.sciencedirect.com/science/article/pii/S0092867421015610
Epigenetic priming in chronic liver disease impacts the transcriptional and genetic landscapes of hepatocellular carcinoma. Gallon J, Coto-Llerena M, Ercan C, Bianco G, Paradiso V, Nuciforo S, Taha-Melitz S, Meier MA, Boldanova T, Pérez-Del-Pulgar S, Rodríguez-Tajes S, von Flüe M, Soysal SD, Kollmar O, Llovet JM, Villanueva A, Terracciano LM, Heim MH, Ng CKY, Piscuoglio S. Mol Oncol. 2022 Feb;16(3):665-682. IF 6.603
febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13154
Immunological Predictors of Dimethyl Fumarate-Induced Lymphopenia. Diebold M, Galli E, Kopf A, Sanderson N, Callegari I, Ingelfinger F, Núñez NG, Benkert P, Kappos L, Kuhle J, Becher B, Claassen M, Derfuss T. Ann Neurol. 2022 May;91(5):676-681. IF 10.422
onlinelibrary.wiley.com/doi/10.1002/ana.26328
Targeting immunoliposomes to EGFR-positive glioblastoma. Kasenda B, König D, Manni M, Ritschard R, Duthaler U, Bartoszek E, Bärenwaldt A, Deuster S, Hutter G, Cordier D, Mariani L, Hench J, Frank S, Krähenbühl S, Zippelius A, Rochlitz C, Mamot C, Wicki A, Läubli H. ESMO Open. 2022 Feb;7(1):100365. IF 6.540
www.sciencedirect.com/science/article/pii/S2059702921003276
Model-based inference of neutralizing antibody avidities against influenza virus. Linnik J, Syedbasha M, Hollenstein Y, Halter J, Egli A, Stelling J. PLoS Pathog. 2022 Jan 31;18(1):e1010243 IF 6.823
www.ncbi.nlm.nih.gov/pmc/articles/PMC8830794/
Direct antimicrobial resistance prediction from clinical MALDI-TOF mass spectra using Machine learning. Weis C, Cuénod A, Rieck B, Dubuis O, Graf S, Lang C, Oberle M, Brackmann M, Søgaard KK, Osthoff M, Borgwardt K, Egli A. Nat Med. 2022 Jan;28(1):164-174. IF: 53.440
www.nature.com/articles/s41591-021-01619-9
Stimulatory MAIT cell antigens reach the circulation and are efficiently metabolised and presented by human liver cells. Lett MJ, Mehta H, Keogh A, Jaeger T, Jacquet M, Powell K, Meier M, Fofana I, Melhem H, Vosbeck J, Cathomas G, Heigl A, Heim MH, Burri E, Mertz KD, Niess JH, Kollmar O, Zech CJ, Ivanek R, Duthaler U, Klenerman P, Stroka D, Filipowicz Sinnreich M:Gut. 2022 Jan 20;gutjnl-2021-324478. doi: 10.1136/gutjnl-2021-324478. IF 23.059
gut.bmj.com/content/early/2022/01/20/gutjnl-2021-324478.long
Standardizing Patient-Derived Organoid Generation Workflow to Avoid Microbial Contamination From Colorectal Cancer Tissues. Marinucci M, Ercan C, Taha-Mehlitz S, Fourie L, Panebianco F, Bianco G, Gallon J, Staubli S, Soysal SD, Zettl A, Rauthe S, Vosbeck J, Droeser RA, Bolli M, Peterli R, von Flüe M, Ng CKY, Kollmar O, Coto-Llerena M, Piscuoglio S. Front Oncol. 2022 Jan 10;11:781833. IF 6.244
www.frontiersin.org/articles/10.3389/fonc.2021.781833/full
Suppression of caspase 8 activity by a coronin 1-PI3Kδ pathway promotes T cell survival independently of TCR and IL-7 signaling. Mori M, Ruer-Laventie J, Duchemin W, Demougin P, Ndinyanka Fabrice T, Wymann MP, Pieters J. Sci Signal. 2021 Dec 21;14(714):eabj0057. IF 8.218
www.science.org/doi/10.1126/scisignal.abj0057
Emergence and function of cortical offset responses in sound termination detection. Solyga M, Barkat TR. eLife. 10:e72240. IF 8.146
elifesciences.org/articles/72240
Task-induced modulations of neuronal activity along the auditory pathway. De Franceschi G, Barkat TR. Cell Reports. Reports 37, 11015. IF 9.423
www.sciencedirect.com/science/article/pii/S2211124721016090
Case Report: Reconstruction of a Large Maxillary Defect with an Engineered, Vascularized, Prefabricated Bone Graft. Ismail T, Haumer A, Lunger A, Osinga R, Kaempfen A, Saxer F, Wixmerten A, Miot S, Thieringer F, Beinemann J, Kunz C, Jaquiéry C, Weikert T, Kaul F, Scherberich A, Schaefer DJ, Martin I. Front Oncol. 11: 775136 (2021). IF 6.244
www.frontiersin.org/articles/10.3389/fonc.2021.775136/full
SMAD4 target genes are part of a transcriptional network that integrates the response to BMP and SHH signaling during early limb bud patterning. Gamart J, Barozzi I, Laurent F, Reinhardt R, Martins LR, Oberholzer T, Visel A, Zeller R, Zuniga A. Development. 148, dev200182. IF 6.868
journals.biologists.com/dev/article/148/23/dev200182/273622/SMAD4-target-genes-are-part-of-a-transcriptional
RBFOX splicing factors contribute to a broad but selective recapitulation of peripheral tissue splicing patterns in the thymus. Jansen K, Shikama-Dorn N, Attar M, Maio S, Lopopolo M, Buck D, Holländer GA, Sansom SN. Genome Res. 2021 Nov;31(11):2022-2034. IF 9.043
genome.cshlp.org/content/31/11/2022.long
NOX1 mediates metabolic heart disease in mice and is upregulated in monocytes of humans with diastolic dysfunction. Xu L, Balzarolo M, Robinson EL, Lorenz V, Verde GD, Joray L, Mochizuki M, Kaufmann BA, Valstar G, de Jager SCA, den Ruijter HM, Heymans S, Pfister O, Kuster GM. Cardiovasc Res. 2021 Nov 26;cvab349. IF 10.787
academic.oup.com/cardiovascres/advance-article/doi/10.1093/cvr/cvab349/6443118
Supervised learning based on tumor imaging and biopsy transcriptomics predicts response of hepatocellular carcinoma to transarterial chemoembolization. Boldanova T, Fucile G, Vosshenrich J, Suslov A, Ercan C, Coto-Llerena M, Terracciano LM, Zech CJ, Boll DT, Wieland S, Heim MH. Cell Rep Med. 2021 Nov 16;2(11):100444.IF: 9.423
www.sciencedirect.com/science/article/pii/S2666379121003128
Chronic inflammation and extracellular matrix-specific autoimmunity following inadvertent periarticular influenza vaccination. Hirsiger JR, Tamborrini G, Harder D, Bantug GR, Hoenger G, Recher M, Marx C, Li QZ, Martin I, Hess C, Scherberich A, Daikeler T, Berger CT. J Autoimmun. 2021 Nov;124:102714. IF 7.094
www.sciencedirect.com/science/article/pii/S0896841121001220
Nose to Spine: spheroids generated by human nasal chondrocytes for scaffold-free nucleus pulposus augmentation. Gryadunova A, Kasamkattil J, Gay MHP, Dasen B, Pelttari K, Mironov V, Martin I, Schären S, Barbero A, Krupkova O, Mehrkens A. Acta Biomater. 134: 240-251 (2021). IF 8.947
www.sciencedirect.com/science/article/pii/S174270612100502X
The Genomic Landscape of Serrated Lesion of the Colorectum: Similarities and Differences With Tubular and Tubulovillous Adenomas. Tornillo L, Lehmann FS, Garofoli A, Paradiso V, Ng CKY, Piscuoglio S. Front Oncol. 2021 Oct 12;11:668466. IF 6.244
www.frontiersin.org/articles/10.3389/fonc.2021.668466/full
Ubiquitous expression of HBsAg from integrated HBV DNA in patients with low viral load. Meier MA, Calabrese D, Suslov A, Terracciano LM, Heim MH, Wieland S. J Hepatol. 2021 Oct;75(4):840-847. IF: 25.083
www.sciencedirect.com/science/article/pii/S0168827821003287
Engineering of fully humanized and vascularized 3D bone marrow niches sustaining undifferentiated human cord blood hematopoietic stem and progenitor cells. Born G, Nikolova M, Scherberich A, Treutlein B, García-García A, Martin I. J Tissue Eng. 12: 1-11 (2021). IF 7.813
journals.sagepub.com/doi/10.1177/20417314211044855
Culturing patient-derived malignant hematopoietic stem cells in engineered and fully humanized 3D niches. García-García A, Klein T, Born G, Hilpert M, Scherberich A, Lengerke C, Skoda RC, Bourgine PE, Martin I. Proc Nat Acad Sci USA. 118(40), e2114227118: 1-10 (2021). IF 10.700
www.pnas.org/doi/10.1073/pnas.2114227118
Spatial regulation by multiple Gremlin1 enhancers provides digit development with cis-regulatory robustness and evolutionary plasticity. Malkmus J, Ramos Martins L, Jhanwar S, Kircher B, Palacio V, Sheth R, Leal F, Duchesne A, Lopez-Rios J, Peterson KA, Reinhardt R, Onimaru K, Cohn MJ, Zuniga A, Zeller R. Nature Commun 12, 5557. IF 14.919
www.ncbi.nlm.nih.gov/pmc/articles/PMC8455560/
Whole-genome sequence-informed MALDI-TOF MS diagnostics reveal importance of Klebsiella oxytoca group in invasive infections: a retrospective clinical study. Cuénod A, Wüthrich D, Seth-Smith HMB, Ott C, Gehringer C, Foucault F, Mouchet R, Kassim A, Revathi G, Vogt DR, von Felten S, Bassetti S, Tschudin- Sutter S, Hettich T, Schlotterbeck G, Homberger C, Casanova C, Moran-Gilad J, Sagi O, Rodríguez-Sánchez B, Müller F, Aerni M, Gaia V, van Dessel H, Kampinga GA, Müller C, Daubenberger C, Pflüger V, Egli A. Genome Med 2021 Sep 13;13(1):150. IF 11.117
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Conserved and species-specific chromatin remodelling and regulatory dynamics during mouse and chicken limb bud development. Jhanwar S, Malkmus J, Stolte J, Romashkina O, Zuniga A, Zeller R. Nature Commun. 12, 5685. IF 14.919
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Systemic identification of novel cancer genes through analysis of deep shRNA perturbation screens. Montazeri H, Coto-Llerena M, Bianco G, Zangene E, Taha-Mehlitz S, Paradiso V, Srivatsa S, de Weck A, Roma G, Lanzafame M, Bolli M, Beerenwinkel N, von Flüe M, Terracciano LM, Piscuoglio S, Ng CKY. Nucleic Acids Res. 2021 Sep 7;49(15):8488-8504. IF 16.971
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Manufacturing of Human Tissues as off-the-Shelf Grafts Programmed to Induce Regeneration. Pigeot S, Klein T, Gullotta F, Dupard SJ, Garcia Garcia A, García-García A, Prithiviraj S, Lorenzo P, Filippi M, Jaquiery C, Kouba L, Asnaghi MA, Raina DB, Dasen B, Isaksson H, Önnerfjord P, Tägil M, Bondanza A, Martin I, Bourgine PE. Adv Mater. 33, 2103737: 1-13 (2021). IF 30.849
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Dual targeting of JAK2 and ERK interferes with the myeloproliferative neoplasm clone and enhances therapeutic efficacy. Brkic S, Stivala S, Santopolo A, Szybinski J, Jungius S, Passweg JR, Tsakiris D, Dirnhofer S, Hutter G, Leonards K, Lischer HEL, Dettmer MS, Neel BG, Levine RL, Meyer SC. Leukemia. 2021 Oct;35(10):2875-2884. IF 11.528
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Engineered nasal cartilage for the repair of osteoarthritic knee cartilage defects. Acevedo Rua L, Mumme M, Manferdini C, Darwiche S, Khalil A, Hilpert M, Buchner DA, Lisignoli G, Occhetta P, von Rechenberg B, Haug M, Schaefer DJ, Jakob M, Caplan A, Martin I, Barbero A, Pelttari K. Sci Transl Med. 13(609), eaaz4499:1-14 (2021). IF 17.992
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Persistent RNA virus infection is short-lived at the single-cell level but leaves transcriptomic footprints. Reuther P, Martin K, Kreutzfeldt M, Ciancaglini M, Geier F, Calabrese D, Merkler D, Pinschewer DD. J Exp Med. (2021) 218 (10): e20210408. IF 14.307
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Interferon lambda 4 impairs hepatitis C viral antigen presentation and attenuates T cell responses. Chen Q, Coto-Llerena M, Suslov A, Teixeira RD, Fofana I, Nuciforo S, Hofmann M, Thimme R, Hensel N, Lohmann V, Ng CKY, Rosenberger G, Wieland S, Heim MH. Nat Commun. 2021 Aug 12;12(1):4882. IF: 14.919
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Thymus extracellular matrix-derived scaffolds support graft-resident thymopoesis and long-term in vitro culure of adult thymic epithelial cells. Asnaghi MA, Barthlott T, Gullotta F, Strusi V, Amovilli A, Hafen K, Srivastava G, Oertle P, Toni R, Wendt D, Holländer GA, Martin I. Adv Funct Mater 31(20):2010747 (1-15) (2021). IF 18.808
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Deep learning enables the automation of grading histological tissue engineered cartilage images for quality control standardization. Power L, Acevedo L, Yamashita R, Rubin D, Martin I, Barbero A. Osteoarthritis Cartilage. 29:433-443 (2021). IF 6.576
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Mass Cytometry of CSF Identifies an MS-Associated B-cell Population. Johansson D, Rauld C, Roux J, Regairaz C, Galli E, Callegari I, Raad L, Waldt A, Cuttat R, Roma G, Diebold M, Becher B, Kuhle J, Derfuss T, Carballido JM, Sanderson NSR. Neurol Neuroimmunol Neuroinflamm. 2021 Feb 15;8(2):e943. IF 8.485
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Adenylosuccinate lyase is oncogenic in colorectal cancer by causing mitochondrial dysfunction and independent activation of NRF2 and mTOR-MYC-axis. Taha-Mehlitz S, Bianco G, Coto-Llerena M, Kancherla V, Bantug GR, Gallon J, Ercan C, Panebianco F, Eppenberger-Castori S, von Strauss M, Staubli S, Bolli M, Peterli R, Matter MS, Terracciano LM, von Flüe M, Ng CKY, Soysal SD, Kollmar O, Piscuoglio S. Theranostics. 2021 Feb 15;11(9):4011-4029. IF 11.556
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Presence of SARS-CoV-2 transcripts in the choroid plexus independent of multiple sclerosis. Fuchs V, Kutza M, Wischnewski S, Deigendesch N, Lutz L, Kulsvehagen L, Ricken G, Kappos L, Tzankov A, Hametner S, Frank S, Schirmer L, Pröbstel AK. Neurol Neuroimmunol Neuroinflamm. 2021; 8(2):e957. IF 8.485
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