Publications
Below you can find a recent publication list of the Department of Biomedicine.
If you are looking for publications of a specific group please refer to the corresponding research group.
August 2021 - December 2023
Development of resistance to type II JAK2 inhibitors in MPN depends on AXL kinase and is targetable. Codilupi T, Szibinki J, Arunasalam S, Jungius S, Dunbar AC, Stivala S, Brkic S, Albrecht C, Vokalova L, Yang JL, Buczak K, Ghosh N, Passweg JR, Rovo A, Angelillo-Scherrer A, Pankov D, Dirnhofer S, Levine RL, Koche R, Meyer SC. Clin Cancer Res. 2024 Feb 1;30(3):586-599. doi: 10.1158/1078-0432.CCR-23-0163. https://aacrjournals.org/clincancerres/article/30/3/586/733543/Development-of-Resistance-to-Type-II-JAK2 |
| Sequential maturation of stimulus-specific adaptation in the mouse lemniscal auditory system. Valerio P, Rechenmann J, Joshi S, De Franceschi G, Barkat Rinaldi T. Sci Adv. 2024 Jan 5;10(1):eadi7624. doi: 10.1126/sciadv.adi7624. Epub 2024 Jan 3. https://pubmed.ncbi.nlm.nih.gov/38170771/ |
| Effects of calibrated blue–yellow changes in light on the human circadian clock. Blume Ch, Cajochen Ch, Schöllhorn I, Slawik H C, Spitschan M. Nat Hum Behav. 2023 Dec 22. doi: 10.1038/s41562-023-01791-7. Online ahead of print. https://www.nature.com/articles/s41562-023-01791-7#author-information |
| The Flt3-inhibitor quizartinib augments apoptosis and promotes maladaptive remodeling after myocardial infarction in mice. Belik DM, Bernasconi R, Xu L, Verde GD, Lorenz V, Grüterich V, Balzarolo M, Mochizuki M, Pfister O, Kuster GM. Apoptosis (2023). doi.org/10.1007/s10495-023-01911-8 https://link.springer.com/article/10.1007/s10495-023-01911-8 |
| Harnessing human adipose-derived stromal cell chondrogenesis in vitro for enhanced endochondral ossification. Chaaban M, Moya A, García-García A, Paillaud R, Schaller R, Klein T, Power L, Buczak K, Schmidt A, Kappos E, Ismail T, Schaefer DJ, Martin I, Scherberich A. Biomaterials. 2023 Dec:303:122387. doi: 10.1016/j.biomaterials.2023.122387. Epub 2023 Nov 6. https://www.sciencedirect.com/science/article/pii/S0142961223003952 |
| Functional characterization of RYR1 variants identified in malignant hyperthermia susceptible individuals. Nodaa Y, Miyoshib H, Benuccia S, Gonzalezc A, Bandschappc O, Girardc T, Trevesa S, Zorzato F. Neuromuscul Disord. 2023 Dec;33(12):951-963. doi: 10.1016/j.nmd.2023.10.019. Epub 2023 Nov 3. https://www.sciencedirect.com/science/article/pii/S0960896623007721 |
| Patient-derived organoids identify tailored therapeutic options and determinants of plasticity in sarcomatoid urothelial bladder cancer. Garioni M, Tschan VJ, Blukacz L, Nuciforo S, Parmentier R, Roma L, Coto-Llerena M, Pueschel H, Piscuoglio S, Vlajnic T, Stenner F, Seifert HH, Rentsch CA, Bubendorf L, Le Magnen C. NPJ Precis Oncol. 2023 Nov 2;7(1):112. doi: 10.1038/s41698-023-00466-w. https://www.nature.com/articles/s41698-023-00466-w |
| Amplicon size and non-encapsidated DNA fragments define plasma cytomegalovirus DNA loads by automated nucleic acid testing platforms: A marker of viral cytopathology? Leuzinger K, Hirsch HH. J Med Virol. 2023 Oct;95(10):e29139. doi: 10.1002/jmv.29139. https://onlinelibrary.wiley.com/doi/10.1002/jmv.29139 |
| CSF1R inhibition with PLX5622 affects multiple immune cell compartments and induces tissue-specific metabolic effects in lean mice. Bosch AJT, Keller L, Steiger L, Rohm TV, Wiedemann SJ, Low AJY, Stawiski M, Rachid L, Roux J, Konrad D, Wueest S, Tugues S, Greter M, Böni-Schnetzler M, Meier DT & Cavelti-Weder C. Diabetologia. 2023 Dec;66(12):2292-2306. doi: 10.1007/s00125-023-06007-1. Epub 2023 Oct 4. https://link.springer.com/article/10.1007/s00125-023-06007-1 |
| Epitope-engineered human hematopoietic stem cells are shielded from CD123-targeted immunotherapy. Marone R, Landmann E, Devaux A, Lepore R, Seyres D, Zuin J, Burgold T, Engdahl C, Capoferri G, Dell’Aglio A, Larrue C, Simonetta F, Rositzka J, Rhiel M, Andrieux G, Gallagher DN, Schröder MS, Wiederkehr A, Sinopoli A, Sacramento VD, Haydn A, Garcia-Prat L, Divsalar C, Camus A, Xu L, Bordoli L, Schwede T, Porteus M, Tamburini J, Corn JE, Cathomen T, Cornu TI, Urlinger S, Jeker LT. J Exp Med. 2023 Dec 4;220(12):e20231235. doi: 10.1084/jem.20231235. Epub 2023 Sep 29. https://rupress.org/jem/article/220/12/e20231235/276306/Epitope-engineered-human-hematopoietic-stem-cells |
| Human blood-labyrinth barrier model to study the effects of cytokines and inflammation. Sekulic M, Puche R, Bodmer D, Petkovic V. Front Mol Neurosci. 2023 Sep 21:16:1243370. doi: 10.3389/fnmol.2023.1243370. eCollection 2023. https://www.frontiersin.org/articles/10.3389/fnmol.2023.1243370/full |
| A method for polyclonal antigen-specific T cell-targeted genome editing (TarGET) for adoptive cell transfer applications. Palianina D, Di Roberto RB, Castellanos-Rueda R, Schlatter F, Reddy ST, Khanna N. Mol Ther Methods Clin Dev. 2023 Jun 19:30:147-160. doi: 10.1016/j.omtm.2023.06.007. eCollection 2023 Sep 14. https://www.sciencedirect.com/science/article/pii/S2329050123000979?via%3Dihub |
| Neurofunctional underpinnings of individual differences in visual episodic memory performance. Geissmann L, Coynel D, Papassotiropoulos A, de Quervain DJF. Nat Commun. 2023 Sep 14;14(1):5694. doi: 10.1038/s41467-023-41380-w. https://www.nature.com/articles/s41467-023-41380-w |
| An Animal Model for Chronic Meningeal Inflammation and Inflammatory Demyelination of the Cerebral Cortex. Enz LS, Winkler A, Wrzos C, Dasen B, Nessler S, Stadelmann C, Schaeren-Wiemers N. Int J Mol Sci. 2023 Sep 9;24(18):13893. doi: 10.3390/ijms241813893. https://www.mdpi.com/1422-0067/24/18/13893 |
| Human blood-labyrinth barrier on a chip: a unique in vitro tool for investigation of BLB properties. Sekulic M, Abdollahi N, Graf L, Deigendesch N, Puche R, Bodmerab D, Petkovic V. RSC Adv. 2023 Aug 25;13(36):25508-25517. doi: 10.1039/d3ra04704k. eCollection 2023 Aug 21. https://pubs.rsc.org/en/content/articlelanding/2023/RA/D3RA04704K |
| mTORC2 regulates auditory hair cell structure and function. Cortada M, Levano S, Hall MN 2, Bodmer D. iScience. 2023 Aug 19;26(9):107687. doi: 10.1016/j.isci.2023.107687. eCollection 2023 Sep 15. https://www.sciencedirect.com/science/article/pii/S2589004223017649?via%3Dihub |
| Exogenous humanin and MOTS-c function as protective agents against gentamicin-induced hair cell damage. Waldmann D, Lu Y, Cortada M, Bodmer D, Huaman SL. Biochem Biophys Res Commun. 2023 Oct 20:678:115-121. doi: 10.1016/j.bbrc.2023.08.033. Epub 2023 Aug 17. https://www.sciencedirect.com/science/article/pii/S0006291X23009798?via%3Dihub |
| Characterization of engraftment dynamics in myelofibrosis after allogeneic hematopoietic cell transplantation including novel conditioning schemes. Jungius S, Adam FC, Grosheintz K, Medinger M, Buser A, Passweg JR, Halter JP, Meyer SC. Front Oncol. 2023 Aug 10:13:1205387. doi: 10.3389/fonc.2023.1205387. eCollection 2023. https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2023.1205387/full |
| Urine CXCL10 to Assess BK Polyomavirus Replication After Kidney Transplantation. Haller J, Diebold M, Leuzinger K, Wehmeier C, Handschin J, Amico P, Hirt-Minkowski P, Steiger J, Dickenmann M, Hirsch HH, Schaub S. Transplantation. 2023 Dec 1;107(12):2568-2574. doi: 10.1097/TP.0000000000004712. Epub 2023 Jul 6. https://journals.lww.com/transplantjournal/fulltext/2023/12000/urine_cxcl10_to_assess_bk_polyomavirus_replication.27.aspx |
Regulator of G-protein signaling 1 critically supports CD8+TRM cell-mediated intestinal immunity. von Werdt D, Gungor B, Barreto de Albuquerque J, Gruber T, Zysset D, Kwong Chung CKC, Corrêa-Ferreira A, Berchtold R, Page N, Schenk M, Kehrl JH, Merkler D, Imhof BA, Stein JV, Abe J, Turchinovich G, Finke D, Hayday AC, Corazza N, Mueller C. Front Immunol. 2023 Apr 20:14:1085895. doi: 10.3389/fimmu.2023.1085895. eCollection 2023. https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2023.1085895/full |
| Targeting the Siglec–sialic acid axis promotes antitumor immune responses in preclinical models of glioblastoma. P Schmassmann, J Roux, A Buck, N Tatari, S Hogan, J Wang, N R Mantuano, R Wieboldt, S Lee, B Snijder, D Kaymak, T A Martins, M F Ritz, T Shekarian, M Mcdaid, M Weller, T Weiss, H Läubli, G Hutter. DOI: 10.1126/scitranslmed.adf5302. https://www.science.org/doi/10.1126/scitranslmed.adf5302 |
| Human epidermis organotypic cultures, a reproducible system recapitulating the epidermis in vitro. Experimental Dermatology. Rishika Agarwal, Tanja Dittmar, Hans-Dietmar Beer, Michael Kunz, Simon Müller, Elisabeth A. Kappos, Emmanuel Contassot, Alexander A. Navarini (2023). 2023;00:1-13. doi:10.1111/exd.14823 https://onlinelibrary.wiley.com/doi/full/10.1111/exd.14823 |
| Iron is a modifier of the phenotypes of JAK2-mutant myeloproliferative neoplasms. Stetka J, Usart M,Kubovcakova L,Rai S, Nageswara Rao T, Sutter J, Hao-Shen H,Dirnhofer S, Geier F, Bader M, Passweg J, Manolova V, Dürrenberger F, Ahmed N, Schroeder T, Ganz T, Nemeth E, Silvestri L, Nai A, Camaschella C and Skoda R. Blood. 2023 Apr 27;141(17):2127-2140. doi: 10.1182/blood.2022017976. 27.04.23 https://pubmed.ncbi.nlm.nih.gov/36758212/ |
| N-acetylcysteine overcomes NF1 loss-driven resistance to PI3Kα inhibition in breast cancer. Auf der Maur P, Trefny MP, Baumann Z, Vulin M, Correia AL, Diepenbruck M, Kramer N, Volkmann K, Preca BT, Ramos P, Leroy C, Eichlisberger T, Buczak K, Zilli F, Okamoto R, Rad R, Jensen MR, Fritsch C, Zippelius A, Stadler MB, Bentires-Alj M. Cell Rep Med. 2023 Apr 18;4(4):101002. doi: 10.1016/j.xcrm.2023.101002. Epub 2023 Apr 11. PMID: 37044095 18.04.23 https://pubmed.ncbi.nlm.nih.gov/37044095/ |
| DNA methylation landscapes of prostate cancer brain metastasis are shaped by early driver genetic alterations. Gallon J, Rodriguez-Calero A, Benjak A, Akhoundova D, Maletti S, Amstutz U, Hewer E, Genitsch V, Fleischmann A, Rushing EJ, Grobholz R, Fischer I, Jochum W, Cathomas G, Osunkoya AO, Bubendorf L, Moch H, Thalmann G, Feng FY, Gillessen S, Ng CKY, Rubin MA, Piscuoglio S. Cancer Res. 2023 Apr 14;83(8):1203-1213. doi: 10.1158/0008-5472.CAN-22-2236. 14.04.23 https://pubmed.ncbi.nlm.nih.gov/36749655/ |
| Pharmacokinetics and Pharmacodynamics of Oral Psilocybin Administration in Healthy Participants. Holze F, Becker AM, Kolaczynska KE, Duthaler U and Liechti ME. Clin Pharmacol Ther. 2023 Apr;113(4):822-831. doi: 10.1002/cpt.2821. Epub 2022 Dec 31. 01.04.23 https://pubmed.ncbi.nlm.nih.gov/36507738/ |
| AXL expression on homeostatic resident liver macrophages is reduced in cirrhosis following GAS6 production by hepatic stellate cells. Holze F, Becker AM, Kolaczynska KE, Duthaler U and Liechti ME. Cell Mol Gastroenterol Hepatol. 2023 Mar 31;S2352-345X(23)00047-4. doi: 10.1016/j.jcmgh.2023. 03.007. Online ahead of print. 31.03.23 https://www.sciencedirect.com/science/article/pii/S2352345X23000474?via%3Dihub |
| Autoimmunity and immunodeficiency associated with monoallelic LIG4 mutations via haploinsufficiency. Jauch A, Bignucolo O, Seki S, Ghraichy M, Delmonte O, von Niederhäusern V, Higgins R, Ghosh A, Nishizawa M, Tanaka M, Baldrich A, Köppen J, Hirsiger J, Hupfer R, Ehl S, Rensing-Ehl A, Hopfer H, Savic Prince S, Daley S, Marquardsen F, Meyer B, Tamm M, Daikeler T, Diesch T, Kühne T, Helbling A, Berkemeier C, Heijnen I, Navarini A, Trück J, de Villartay J.-P., Oxenius A, Berger Ch, Hess Ch, D Notarangelo L, Yamamoto H, Recher M. Allergy Clin Immunol. 2023 Mar 31;S0091-6749(23)00422-0. doi: 10.1016/j.jaci.2023.03.022. Online ahead of print. 31.03.23 https://pubmed.ncbi.nlm.nih.gov/37004747/ |
| VEGF dose controls the coupling of angiogenesis and osteogenesis in engineered bone. Grosso A, Lunger A, Burger MG, Briquez PS, Mai F, Hubbell JA, Schaefer DJ, Banfi A, Di Maggio N. NPJ Regen Med. 2023 Mar 13;8(1):15. doi: 10.1038/s41536-023-00288-1. 13.03.23 https://pubmed.ncbi.nlm.nih.gov/36914692/ |
| Lung versus gut exposure to air pollution particles differentially affect metabolic health in mice. Bosch AJT, Rohm TV, AlAsfoor S, Low AJY, Keller L, Baumann Z, Parayil N, Stawiski M, Rachid L, Dervos T, Mitrovic S, Meier DT, Cavelti-Weder C. Part Fibre Toxicol. 2023 Mar 9;20(1):7. doi: 10.1186/s12989-023-00518-w. 09.03.23 https://pubmed.ncbi.nlm.nih.gov/36895000/ |
| Good Manufacturing Practice-compliant change of raw material in the manufacturing process of a clinically used advanced therapy medicinal product-a comparability study. Wixmerten A, Miot S, Bittorf P, Wolf F, Feliciano S, Hackenberg S, Häusner S, Krenger W, Haug M, Martin I, Pullig O, Barbero A. Cytotherapy. 2023 May;25(5):548-558. doi: 10.1016/j.jcyt.2023.01.003. Epub 2023 Mar 7. PMID: 36894437. 07.03.23 https://pubmed.ncbi.nlm.nih.gov/36894437/ |
| Quantitative proteomic analysis of skeletal muscles from wild-type and transgenic mice carrying recessive Ryr1 mutations linked to congenital myopathies. Eckhardt J, Ruiz A, Koenig S, Frieden M, Meier H, Schmidt A, Treves S, Zorzato F. Elife. 2023 Mar 2;12:e83618. doi: 10.7554/eLife.83618. 02.03.23 https://pubmed.ncbi.nlm.nih.gov/36862731/ |
| T-cadherin is a novel regulator of pericyte function during angiogenesis. Dasen B, Pigeot S, Born GM, Verrier S, Rivero O, Dittrich PS, Martin I, Filippova M. Am J Physiol Cell Physiol, Feb 20, Online, ahead of print (2023). doi: 10.1152/ajpcell.00326.2022. PMID: 36802732. 20.02.23 https://pubmed.ncbi.nlm.nih.gov/36802732/ |
| Doublecortin and Glypican-2 concentrations in the cerebrospinal fluid from infants are developmentally downregulated. Brégère C, Fisch U, Halbeisen FS, Schneider C, Dittmar T, Stricker S, Aghlmandi S, Guzman R. PLoS One. 2023 Feb 17;18(2):e0279343. doi: 10.1371/journal.pone.0279343. eCollection 2023. 17.02.23 https://pubmed.ncbi.nlm.nih.gov/36800341/ |
| Dynamics of antibody titers to SARS-CoV-2 and clinical outcomes after sotrovimab pre-exposure prophylaxis early after allogeneic hematopoietic stem cell transplantation. Capoferri G, Walti CS, Urwyler P, Ragozzino S, Passweg JR, Halter J, Battegay M, Baettig V, Weisser M, Arnold B, Morin B, Guetlin Y, Torres DA, Barut GT, Thiel V, Egli A, Drexler B, Khanna N. Bone Marrow Transplant. 2023 Feb 16;1-3. doi: 10.1038/s41409-023-01936-2. Online ahead of print. 16.02.23 https://pubmed.ncbi.nlm.nih.gov/36797421/ |
| Impact of nucleic acid extraction procedures on human papillomavirus (HPV) detection and genotyping. Naegele K, Weissbach FH, Leuzinger K, Gosert R, Bubendorf L, Hirsch HH. J Med Virol. 2023 Feb;95(2):e28583. doi: 10.1002/jmv.28583.PMID: 36794677. 16.02.23 https://pubmed.ncbi.nlm.nih.gov/36794677/ |
| The alarmin interleukin-33 promotes the expansion and preserves the stemness of Tcf-1+ CD8+ T cells in chronic viral infection. AF Marx, Kallert SM, Brunner TM, Villega JA, Geier F, Fixemer J, Abreu-Mota T, Reuther P, Bonilla WV, Fadejeva J, Kreutzfeldt M, Wagner I, Aparicio-Domingo P, Scarpellino L, Charmoy M, Utzschneider DT, Hagedorn C, Lu M, Cornille K, Stauffer K, Kreppel F, Merkler D, Zehn D, Held W, Luther SA, Löhning M, D Pinschewer DD. Immunity. 2023 Feb 14;S1074-7613(23)00041-9. doi: 10.1016/j.immuni.2023.01.029. Online ahead of print. 14.02.23 https://pubmed.ncbi.nlm.nih.gov/36809763/ |
| Ketanserin Reverses the Acute Response to LSD in a Randomized, Double-Blind, Placebo-Controlled, Crossover Study in Healthy Participants. Becker AM, Klaiber A, Holze F, Istampoulouoglou I, Duthaler U, Varghese N, Eckert A, Liechti ME. Int J Neuropsychopharmacol. 2023 Feb 14;26(2):97-106. doi: 10.1093/ijnp/pyac075. 14.02.23 https://pubmed.ncbi.nlm.nih.gov/36342343/ |
| Human 3D nucleus pulposus microtissue model to evaluate the potential of pre-conditioned nasal chondrocytes for the repair of degenerated intervertebral disc. Kasamkattil J, Gryadunova A, Schmid R, Gay-Dujak MHP, Dasen B, Hilpert M, Pelttari K, Martin I, Schären S, Barbero A, Krupkova O, Mehrkens A. " Front Bioeng Biotechnol. 2023 Feb 14;11:1119009. doi: 10.3389/fbioe.2023.1119009. eCollection 2023. ". 14.02.23 https://pubmed.ncbi.nlm.nih.gov/36865027/ |
| MRGPRX2: A novel biomarker in mastocytosis? Konantz M, Merkel T, Meyer SC, Hartmann K. J Allergy Clin Immunol Pract. 2023 Feb;11(2):669-671. doi: 10.1016/j.jaip.2022.10.053. PMID: 36759088. 11.02.23 https://pubmed.ncbi.nlm.nih.gov/36759088/ |
| Serum Glial Fibrillary Acidic Protein Compared With Neurofilament Light Chain as a Biomarker for Disease Progression in Multiple Sclerosis. Meier S, Willemse EAJ, Schaedelin S, Oechtering J, Lorscheider J, Melie-Garcia L, Cagol A, Barakovic M, Galbusera R, Subramaniam S, Barro C, Abdelhak A, Thebault S, Achtnichts L, Lalive P, Müller S, Pot C, Salmen A, Disanto G, Zecca C, D'Souza M, Orleth A, Khalil M, Buchmann A, Du Pasquier R, Yaldizli Ö, Derfuss T, Berger K, Hermesdorf M, Wiendl H, Piehl F, Battaglini M, Fischer U, Kappos L, Gobbi C, Granziera C, Bridel C, Leppert D, Maceski AM, Benkert P, Kuhle J. JAMA Neurol. 2023 Feb 6;80(3):287-297. doi: 10.1001/jamaneurol.2022.5250. Online ahead of print. 06.02.23 https://pubmed.ncbi.nlm.nih.gov/36745446/ |
| The NFIA-ETO2 fusion blocks erythroid maturation and induces pure erythroid leukemia in cooperation with mutant TP53. Piqué-Borràs MR, Jevtic Z, Otzen Bagger F, Seguin J, Sivalingam R, Bezerra MF, Louwaige A, Juge S, Nellas I, Ivanek R, Tzankov A, Moll U, Cantillo OV, Schulz-Heddergott R, Fagnan A, Mercher T, Schwaller J. Blood. 2023 Feb 3:blood.2022017273. doi: 10.1182/blood.2022017273. Online ahead of print. 03.02.23 https://www.sciencedirect.com/science/article/pii/S0006497123003105?via%3Dihub |
| Deletion of SNX9 alleviates CD8 T cell exhaustion for effective cellular cancer immunotherapy. Marcel P. Trefny, Nicole Kirchhammer, Priska Auf der Maur, Marina Natoli, Dominic Schmid, Markus Germann, Laura Fernandez Rodriguez, Petra Herzig, Jonas Lötscher, Maryam Akrami, Jane C. Stinchcombe, Michal A. Stanczak, Andreas Zingg, Melanie Buchi, Julien Roux, Romina Marone, Leyla Don, Didier Lardinois, Mark Wiese, Lukas T. Jeker, Mohamed Bentires-Alj, Jérémie Rossy, Daniela S. Thommen, Gillian M. Griffiths, Heinz Läubli, Christoph Hess, Alfred Zippelius. Nat Commun 14, 86 (2023). https://doi.org/10.1038/s41467-022-35583-w. 02.02.23 https://www.nature.com/articles/s41467-022-35583-w |
| A patient-centric modeling framework captures recovery from SARS-CoV-2 infection. Ruffieux H, Hanson AL, Lodge S, Lawler NG, Whiley L, Gray N, Nolan TH, Bergamaschi L, Mescia F, Turner L, de Sa A, Pelly VS, The Cambridge Institute of Therapeutic Immunology and Infectious Disease-National Institute of Health Research (CITIID-NIHR) BioResource COVID-19 Collaboration*, Kotagiri P, Kingston N, Bradley JR, Holmes E, Wist J, Nicholson JK, Lyons PA, Smith KGC, Richardson S, Bantug GR & Hess C. Nat Immunol. 2023 Feb;24(2):349-358. doi: 10.1038/s41590-022-01380-2. Epub 2023 Jan 30. 30.01.23 https://pubmed.ncbi.nlm.nih.gov/36717723/ |
| Soluble amyloid-β precursor peptide does not regulate GABAB receptor activity. Rem PD, Sereikaite V, Fernández-Fernández D, Reinartz S, Ulrich D, Fritzius T, Trovo L, Roux S, Chen Z, Rondard P, Pin JP, Schwenk J, Fakler B, Gassmann M, Rinaldi Barkat T, Strømgaard K, Bettler B. Elife. 2023 Jan 23;12:e82082. doi: 10.7554/eLife.82082. 23.01.23 https://pubmed.ncbi.nlm.nih.gov/36688536/ |
| Classic psychedelics do not affect T cell and monocyte immune responses. Rudin D, Areesanan A, Liechti ME and Gründemann C. Front Psychiatry. 2023 Jan 20;14:1042440. doi: 10.3389/fpsyt.2023.1042440. eCollection 2023. 20.01.23 https://pubmed.ncbi.nlm.nih.gov/36741125/ |
| Investigation of morpholine isosters for the development of a potent, selective and metabolically stable mTOR kinase inhibitor. De Pascale M, Bissegger L, Tarantelli C, Beaufils F, Prescimone A, Hedad HMS, Kayali O, Orbegozo C, Raguž L, Schaefer T, Hebeisen P, Bertoni F, Wymann MP, Borsari C. European Journal of Medicinal Chemistry. Volume 248, 15 February 2023, 115038, doi: 10.1016/j.ejmech.2022.115038. 28.12.22 |
| Engineering of immunoinstructive extracellular matrices for enhanced osteoinductivity. Garcia-Garcia A, Pigeot S, Martin I. Bioactive Materials, 24: 174-184 (2023). doi: 10.1016/j.bioactmat.2022.12.017. PMID: 36606254. 21.12.22 https://pubmed.ncbi.nlm.nih.gov/36606254/ |
| Liraglutide Lowers Endothelial Vascular Cell Adhesion Molecule-1 in Murine Atherosclerosis Independent of Glucose Levels. Punjabi M, Kosareva A, Xu L, Ochoa-Espinosa A, Decembrini S, Hofmann G, Wyttenbach S, Rolin B, Nyberg M, Kaufmann BA. JACC Basic Transl Sci. 2022 Dec 7;8(2):189-200. doi: 10.1016/j.jacbts.2022.08.002. eCollection 2023 Feb. 07.12.23 https://www.sciencedirect.com/science/article/pii/S2452302X22003023 |
| BK Polyomavirus Consensus. Hirsch HH, Mengel M, Kamar N. Clinical Infectious Diseases. Clin Infect Dis. 2022 Nov 30;75(11):2046-2047. doi: 10.1093/cid/ciac594. 30.11.22 https://pubmed.ncbi.nlm.nih.gov/35856634/ |
| Mini- and macro-scale direct perfusion bioreactors with optimized flow for engineering 3D tissues. Born G, Plantier E, Nannini G, Caimi A, Mazzoleni A, Asnaghi MA, Muraro MG, Scherberich A, Martin I, García-García A. Biotechnol. Feb;18(2): e2200405. doi: 10.1002/biot.202200405. Epub Feb 2023. doi: 10.1002/biot.202200405. PMID 36428229. 25.11.22 https://pubmed.ncbi.nlm.nih.gov/36428229/ |
| Defective Desmosomal Adhesion Causes Arrhythmogenic Cardiomyopathy by Involving an Integrin-αVβ6/TGF-β Signaling Cascade. Schinner C, Xu L, Franz H, Zimmermann A, Wanuske MT, Rathod M, Hanns P, Geier F, Pelczar P, Liang Y, Lorenz V, Stüdle C, Maly PI, Kauferstein S, Beckmann BM, Sheikh F, Kuster GM, Spindler V. Circulation. Circulation. 2022 Nov 22;146(21):1610-1626. doi: 10.1161/CIRCULATIONAHA.121.057329. 22.11.22 https://pubmed.ncbi.nlm.nih.gov/36268721/ |
| Molecular Characterization of BK Polyomavirus Replication in Allogeneic Hematopoietic Cell Transplantation. Leuzinger K, Kaur A, Wilhelm M, Frank K, Hillenbrand CA, Weissbach FH, Hirsch HH. The Journal of Infectious Diseases. J Infect Dis. 2022 Nov 21;jiac450. doi: 10.1093/infdis/jiac450. Online ahead of print. 21.11.22 https://pubmed.ncbi.nlm.nih.gov/36409589/ |
| Deciphering molecular and cellular ex vivo responses to bispecific antibodies PD1-TIM3 and PD1-LAG3 in human tumors. Natoli M, Hatje K, Gulati P, Junker F, Herzig P, Jiang Z, Davydov II, Germann M, Trüb M, Marbach D, Zwick A, Weber P, Seeber S, Wiese M, Lardinois D, Heinzelmann-Schwarz V, Rosenberg R, Tietze L, Mertz KD, Umaña P, Klein C, Codarri-Deak L, Kao H, Zippelius A. Journal for Immunotherapy of Cancer. J Immunother Cancer. 2022 Nov;10(11):e005548. doi: 10.1136/jitc-2022-005548. 10.11.22 https://pubmed.ncbi.nlm.nih.gov/36319064/ |
| Severe Neuro-COVID is associated with peripheral immune signatures, autoimmunity and neurodegeneration: a prospective cross-sectional study. Etter MM, Martins TA, Kulsvehagen L, Pössnecker E, Duchemin W, Hogan S, Sanabria-Diaz G, Müller J, Chiappini A, Rychen J, Eberhard N, Guzman R, Mariani L, Melie-Garcia L, Keller E, Jelcic I, Pargger H, Siegemund M, Kuhle J, Oechtering J, Eich C, Tzankov A, Matter MS, Uzun S, Yaldizli Ö, Lieb JM, Psychogios MN, Leuzinger K, Hirsch HH, Granziera C, Pröbstel AK, Hutter G. Nature Communications. Nat Commun. 2022 Nov 9;13(1):6777. doi: 10.1038/s41467-022-34068-0. 09.11.22 https://pubmed.ncbi.nlm.nih.gov/36351919/ |
| Review: Combination cancer immunotherapies: Emerging treatment strategies adapted to the tumor microenvironment. Kirchhammer N, Trefny MP, Auf der Maur P, Läubli H, Zippelius A. Science Translational Medicine. Sci Transl Med. 2022 Nov 9;14(670):eabo3605. doi: 10.1126/scitranslmed.abo3605. Epub 2022 Nov 9. 09.11.22 https://pubmed.ncbi.nlm.nih.gov/36350989/ |
| Targeting cancer glycosylation repolarizes tumor-associated macrophages allowing effective immune checkpoint blockade. Stanczak MA, Mantuano NR, Kirchhammer N, Sanin DE, Jacob F, Coelho R, Everest-Dass AV, Wang J, Trefny MP, Monaco G, Bärenwaldt A, Gray MA, Petrone A, Kashyap AS, Glatz K, Kasenda B, Normington K, Broderick J, Peng L, Pearce OMT, Pearce EL, Bertozzi CR, Zippelius A, Läubli H. Science Translational Medicine. Transl Med. 2022 Nov 2;14(669):eabj1270. doi: 10.1126/scitranslmed.abj1270. Epub 2022 Nov 2. 02.11.22 https://pubmed.ncbi.nlm.nih.gov/36322632/ |
| «Overlapping gene dependencies for PARP inhibitors and carboplatin response identified by functional CRISPR-Cas9 screening in ovarian cancer». Coelho R, Tozzi A, Disler M, Lombardo F, Fedier A, López MN, Freuler F, Jacob F, Heinzelmann-Schwarz V. Cell, Death and Disease. Death Dis. 2022 Oct 28;13(10):909. doi: 10.1038/s41419-022-05347-x. 28.10.22 https://pubmed.ncbi.nlm.nih.gov/36307400/ |
| Forced expression of the non-coding RNA miR-17~92 restores activation and function in CD28-deficient CD4+ T cells. Dölz M, Hasiuk M, Gagnon JD, Kornete M, Marone R, Bantug G, Kageyama R, Hess C, Ansel KM, Seyres D, Roux J, T Jeker LT. iScience. Science. 2022 Oct 17;25(11):105372. doi: 10.1016/j.isci.2022.105372. eCollection 2022 Nov 18. 17.10.22 https://pubmed.ncbi.nlm.nih.gov/36388982/ |
| Stereospecific Synthesis of Substituted Sulfamidates as Privileged Morpholine Building Blocks. Stojiljkovic, U., Meyer, C., Boulay, P., Hebeisen, P., Rageot, D., Wymann, M., Borsari, C. Synthesis. Synthesis 2022, Doi: 10.1055/a-1915-7794. 10.10.22 http://dx.doi.org/10.1055/a-1915-7794 |
| Comment: Two-drug trick to target the brain blocks toxicity in the body. Wymann MP, Borsari C. Nature. Comment Nature. 2022 Sep;609(7928):681-683. doi: 10.1038/d41586-022-02892-5. 14.09.22 https://www.nature.com/articles/d41586-022-02892-5 |
| Receptor clustering and pathogenic complement activation in myasthenia gravis depend on synergy between antibodies with multiple subunit specificities. Rose N, Holdermann S, Callegari I, Kim H, Fruh I, Kappos L, Kuhle J, Müller M, Sanderson NSR, Derfuss T. Acta Neuropathologica. Acta Neuropathol. 2022 Nov;144(5):1005-1025. 08.09.22 https://pubmed.ncbi.nlm.nih.gov/36074148/ |
| Therapeutic arterio-genesis promotes wound healing in diabetic mice. D’Amico R, Malucelli C, Uccelli A, Grosso A, Di Maggio N, Briquez PS, Hubbell JA, Wolff T, Gürke L, Mujagic E, Gianni-Barrera R and Banfi A. J Tissue Eng. 2022 Sep 6;13:20417314221119615. doi: 10.1177/20417314221119615. eCollection 2022 Jan-Dec. 06.09.22 https://pubmed.ncbi.nlm.nih.gov/36093431/ |
| Low Baseline but Not Delta Cortisol Relates to 28-Day Transplant-Free Survival in Acute and Acute-on-Chronic Liver Failure. Roth S, Flint E, Ghataore L, Patel VC, Singanayagam A, Vincent RP, Triantafyllou E, Ma Y, Bernal W, Auzinger G, Heneghan M, Antoniades C, Christ-Crain M, McPhail MJW, Taylor DR, Wendon J, Bernsmeier C. Gastro Hep Advances. Gastro Hep Advances. 2022. Vol 2(1). p72-82. Published online: September 03, 2022, DOI:https://doi.org/10.1016/j.gastha.2022.08.006. 05.09.22 https://pubmed.ncbi.nlm.nih.gov/35857639/ https://www.sciencedirect.com/science/article/pii/S2772572322001479 |
| Targeted transcript analysis in muscles from patients with genetically diverse congenital myopathies. Bachmann C, Franchini M, Van den Bersselaar LR, Kruijt N, Voermans NC, Bouman K, Kamsteeg EJ, Knop KC, Ruggiero L, Santoro L, Nevo Y, Wilmshurst J, Vissing J, Sinnreich M, Zorzato D, Muntoni F, Jungbluth H, Zorzato F, Treves S. Brain Communications. Brain Communications, Volume 4, Issue 5, 2022, fcac224, https://doi.org/10.1093/braincomms/fcac224. 02.09.22 https://academic.oup.com/braincomms/article/4/5/fcac224/6687656 |
| Small-diameter bacterial cellulose-based vascular grafts for coronary artery bypass grafting in a pig model. Fusco D, Meissner F, Podesser BK, Marsano A, Grapow M, Eckstein F, Winkler B. frontiers. Front Cardiovasc Med. 2022 Sep 26;9:881557. doi: 10.3389/fcvm.2022.881557. eCollection 2022. 26.08.22 https://pubmed.ncbi.nlm.nih.gov/36225961/ |
| Mycobacterium abscessus pathogenesis identified by phenogenomic analyses. Boeck L, Burbaud S, Skwark M, Pearson WH, Sangen J, Wuest AW, Marshall EKP, Weimann A, Everall I, Bryant JM, Malhotra S, Bannerman BP, Kierdorf K, Blundell TL, Dionne MS, Parkhill J, Andres Floto R. Nature Microbiology. Nat Microbiol. 2022 Sep;7(9):1431-1441. 25.08.22. https://www.nature.com/articles/s41564-022-01204-x |
| Review: Siglec receptors as new immune checkpoints in cancer. Stanczak MA, Läubli H. Molecular Aspects of Medicine. Mol Aspects Med. 2022 Aug 7;101112. doi: 10.1016/j.mam.2022.101112. 07.08.22 https://pubmed.ncbi.nlm.nih.gov/35948467/ |
| C1q as a target molecule to treat human disease: What do mouse studies teach us? Schulz K, Trendelenburg M. Front Immunol. Front Immunol. 2022 Aug 3;13:958273. doi: 10.3389/fimmu.2022.958273. 03.08.22 https://pubmed.ncbi.nlm.nih.gov/35990646/ |
| Anti-C1q autoantibodies from systemic lupus erythematosus patients enhance CD40-CD154-mediated inflammation in peripheral blood mononuclear cells invitro. Rabatscher PA, Trendelenburg M. Clinical & Translational Immunology. Clin Transl Immunology. 2022 Aug 2;11(8):e1408. doi: 10.1002/cti2.1408. 02.08.22 https://pubmed.ncbi.nlm.nih.gov/35928801/ |
| NK cells with tissue-resident traits shape response to immunotherapy by inducing adaptive antitumor immunity. Kirchhammer N, Trefny MP, Natoli M, Brücher D, Smith SN, Werner F, Koch V, Schreiner D, Bartoszek E, Buchi M, Schmid M, Breu D, Hartmann KP, Zaytseva P, Thommen DS, Läubli H, Böttcher JP, Stanczak MA, Kashyap AS, Plückthun A, Zippelius A. Science Translational Medicine. Sci Transl Med. 2022 Jul 13;14(653):eabm9043. doi: 10.1126/scitranslmed.abm9043. Epub 2022 Jul 13. 13.07.22 https://pubmed.ncbi.nlm.nih.gov/35857639/ |
| Safe administration of subsequent mRNA COVID-19 vaccine doses following a possible allergic reaction to the first dose. Roth MS, Chantraine S, Morales Mateluna CA, Hartmann K*, Berger CT* (*equally). The Journal of the European Academy of Dermatology and Venereology. J Eur Acad Dermatol Venereol. 2022 Nov;36(11):e880-e883. doi: 10.1111/jdv.18387. Epub 2022 Jul 12. 20.06.22 https://onlinelibrary.wiley.com/doi/10.1111/jdv.18387 |
| Integrative proteogenomic characterization of hepatocellular carcinoma across etiologies and stages. Ng CKY, Dazert E, Boldanova T, Coto-Llerena M, Nuciforo S, Ercan C, Suslov A, Meier MA, Bock T, Schmidt A, Ketterer S, Wang X, Wieland S, Matter MS, Colombi M, Piscuoglio S, Terracciano LM, Hall MN, Heim MH. Nat Commun. 2022 May 4;13(1):2436. https://www.nature.com/articles/s41467-022-29960-8#disqus_thread |
| Alterations in homologous recombination repair genes in prostate cancer brain metastases. Rodriguez-Calero A, Gallon J, Akhoundova D, Maletti S, Ferguson A, Cyrta J, Amstutz U, Garofoli A, Paradiso V, Tomlins SA, Hewer E, Genitsch V, Fleischmann A, Vassella E, Rushing EJ, Grobholz R, Fischer I, Jochum W, Cathomas G, Osunkoya AO, Bubendorf L, Moch H, Thalmann G, Ng CKY, Gillessen S, Piscuoglio S, Rubin MA. Nat Commun. 2022 May 3;13(1):2400. https://www.nature.com/articles/s41467-022-30003-5.pdf |
| Targeting colonic macrophages improves glycemic control in high-fat diet-induced obesity. Rohm TV, Keller L, Bosch AJT, AlAsfoor S, Baumann Z, Thomas A, Wiedemann SJ, Steiger L, Dalmas E, Wehner J, Rachid L, Mooser C, Yilmaz B, Fernandez Trigo N, Jauch AJ, Wueest S, Konrad D, Henri S, Niess JH, Hruz P, Ganal-Vonarburg SC, Roux J, Meier DT, Cavelti-Weder C. Commun Biol. 2022 Apr 19;5(1):370. https://www.nature.com/articles/s42003-022-03305-z |
| Identification of TPM2 and CNN1 as Novel Prognostic Markers in Functionally Characterized Human Colon Cancer-Associated Stromal Cells. Mele V, Basso C, Governa V, Glaus Garzon JF, Muraro MG, Däster S, Nebiker CA, Mechera R, Bolli M, Schmidt A, Geiger R, Spagnoli GC, Christoforidis D, Majno PE, Borsig L, Iezzi G. Cancers (Basel). 2022 Apr 16;14(8):2024. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025001/ |
| Covalent Proximity Scanning of a Distal Cysteine to Target PI3Kα. Borsari C, Keles E, McPhail JA, Schaefer A, Sriramaratnam R, Goch W, Schaefer T, De Pascale M, Bal W, Gstaiger M, Burke JE, Wymann MP. J Am Chem Soc. 2022 Apr 13;144(14):6326-6342. https://pubs.acs.org/doi/10.1021/jacs.1c13568 |
| Serum neurofilament light chain for individual prognostication of disease activity in people with multiple sclerosis: a retrospective modelling and validation study. Benkert P, Meier S, Schaedelin S, Manouchehrinia A, Yaldizli Ö, Maceski A, Oechtering J, Achtnichts L, Conen D, Derfuss T, Lalive PH, Mueller C, Müller S, Naegelin Y, Oksenberg JR, Pot C, Salmen A, Willemse E, Kockum I, Blennow K, Zetterberg H, Gobbi C, Kappos L, Wiendl H, Berger K, Sormani MP, Granziera C, Piehl F, Leppert D, Kuhle J; NfL Reference Database in the Swiss Multiple Sclerosis Cohort Study Group. Lancet Neurol. 2022 Mar;21(3):246-257. https://www.sciencedirect.com/science/article/pii/S1474442222000096?via=ihub |
| Determinants of SARS-CoV-2 transmission to guide vaccination strategy in an urban area. Brüningk SC, Klatt J, Stange M, Mari A, Brunner M, Roloff TC, Seth-Smith HMB, Schweitzer M, Leuzinger K, Søgaard KK, Albertos Torres D, Gensch A, Schlotterbeck AK, Nickel CH, Ritz N, Heininger U, Bielicki J, Rentsch K, Fuchs S, Bingisser R, Siegemund M, Pargger H, Ciardo D, Dubuis O, Buser A, Tschudin-Sutter S, Battegay M, Schneider-Sliwa R, Borgwardt KM, Hirsch HH, Egli A. Virus Evol. 2022 Mar 17;8(1):veac002. https://academic.oup.com/ve/article/8/1/veac002/6549831?login=true |
| Epithelial GPR35 protects from Citrobacter rodentium infection by preserving goblet cells and mucosal barrier integrity. Melhem H, Kaya B, Kaymak T, Wuggenig P, Flint E, Roux J, Oost KC, Cavelti-Weder C, Balmer ML, Walser JC, Morales RA, Riedel CU, Liberali P, Villablanca EJ, Niess JH. Mucosal Immunol. 2022 Mar;15(3):443-458. https://www.nature.com/articles/s41385-022-00494-y |
| T-cadherin Expressing Cells in the Stromal Vascular Fraction of Human Adipose Tissue: Role in Osteogenesis and Angiogenesis. Guerrero J, Dasen B, Frismantiene A, Pigeot S, Ismail T, Schaefer DJ, Philippova M, Resink TJ, Martin I, Scherberich A. Stem Cells Transl Med. 11(2): 213-229 (2022). https://academic.oup.com/stcltm/article/11/2/213/6544662?login=true |
| Siglec receptors modulate dendritic cell activation and antigen presentation to T cells in cancer. Wang J, Manni M, Bärenwaldt A, Wieboldt R, Kirchhammer N, Ivanek R, Stanczak M, Zippelius A, König D, Rodrigues Manutano N, Läubli H. Front Cell Dev Biol. 2022 Mar 3;10:828916. https://academic.oup.com/stcltm/article/11/2/213/6544662?login=true |
| Improvement of muscle strength in a mouse model for congenital myopathy treated with HDAC and DNA methyltransferase inhibitors. Ruiz A, Benucci S, Duthaler U, Bachmann C, Franchini M, Noreen F, Pietrangelo L, Protasi F, Treves S, Zorzato F. eLife. 2022 Mar 3;11:e73718. https://elifesciences.org/articles/73718 |
| Engineering of Tracheal Grafts Based on Recellularization of Laser-Engraved Human Airway Cartilage Substrates. Baranovskii D, Demner J, Nürnberger S, Lyundup A, Redl H, Hilpert M, Pigeot S, Krasheninnikov M, Krasilnikova O, Klabukov I, Parshin V, Martin I, Lardinois D, Barbero A. Cartilage. 1-12 (2022). https://journals.sagepub.com/doi/10.1177/19476035221075951?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed+ |
| Magnesium sensing via LFA-1 regulates CD8 + T cell effector function. Lötscher J, Martí I Líndez AA, Kirchhammer N, Cribioli E, Giordano Attianese GMP, Trefny MP, Lenz M, Rothschild SI, Strati P, Künzli M, Lotter C, Schenk SH, Dehio P, Löliger J, Litzler L, Schreiner D, Koch V, Page N, Lee D, Grählert J, Kuzmin D, Burgener AV, Merkler D, Pless M, Balmer ML, Reith W, Huwyler J, Irving M,King CG, Zippelius A, Hess C. Cell. 2022 Feb 17;185(4):585-602. e29. https://www.sciencedirect.com/science/article/pii/S0092867421015610?via=ihub |
| Epigenetic priming in chronic liver disease impacts the transcriptional and genetic landscapes of hepatocellular carcinoma. Gallon J, Coto-Llerena M, Ercan C, Bianco G, Paradiso V, Nuciforo S, Taha-Melitz S, Meier MA, Boldanova T, Pérez-Del-Pulgar S, Rodríguez-Tajes S, von Flüe M, Soysal SD, Kollmar O, Llovet JM, Villanueva A, Terracciano LM, Heim MH, Ng CKY, Piscuoglio S. Mol Oncol. 2022 Feb;16(3):665-682. https://febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13154 |
| Immunological Predictors of Dimethyl Fumarate-Induced Lymphopenia. Diebold M, Galli E, Kopf A, Sanderson N, Callegari I, Ingelfinger F, Núñez NG, Benkert P, Kappos L, Kuhle J, Becher B, Claassen M, Derfuss T. Ann Neurol. 2022 May;91(5):676-681. https://onlinelibrary.wiley.com/doi/10.1002/ana.26328 |
| Targeting immunoliposomes to EGFR-positive glioblastoma. Kasenda B, König D, Manni M, Ritschard R, Duthaler U, Bartoszek E, Bärenwaldt A, Deuster S, Hutter G, Cordier D, Mariani L, Hench J, Frank S, Krähenbühl S, Zippelius A, Rochlitz C, Mamot C, Wicki A, Läubli H. ESMO Open. 2022 Feb;7(1):100365. https://www.sciencedirect.com/science/article/pii/S2059702921003276?via%3Dihub |
| Model-based inference of neutralizing antibody avidities against influenza virus. Linnik J, Syedbasha M, Hollenstein Y, Halter J, Egli A, Stelling J. PLoS Pathog. 2022 Jan 31;18(1):e1010243 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8830794/ |
| Direct antimicrobial resistance prediction from clinical MALDI-TOF mass spectra using Machine learning. Weis C, Cuénod A, Rieck B, Dubuis O, Graf S, Lang C, Oberle M, Brackmann M, Søgaard KK, Osthoff M, Borgwardt K, Egli A. Nat Med. 2022 Jan;28(1):164-174. https://www.nature.com/articles/s41591-021-01619-9 |
| Stimulatory MAIT cell antigens reach the circulation and are efficiently metabolised and presented by human liver cells. Lett MJ, Mehta H, Keogh A, Jaeger T, Jacquet M, Powell K, Meier M, Fofana I, Melhem H, Vosbeck J, Cathomas G, Heigl A, Heim MH, Burri E, Mertz KD, Niess JH, Kollmar O, Zech CJ, Ivanek R, Duthaler U, Klenerman P, Stroka D, Filipowicz Sinnreich M:Gut. 2022 Jan 20;gutjnl-2021-324478. doi: 10.1136/gutjnl-2021-324478. https://gut.bmj.com/content/early/2022/01/20/gutjnl-2021-324478.long |
| Standardizing Patient-Derived Organoid Generation Workflow to Avoid Microbial Contamination From Colorectal Cancer Tissues. Marinucci M, Ercan C, Taha-Mehlitz S, Fourie L, Panebianco F, Bianco G, Gallon J, Staubli S, Soysal SD, Zettl A, Rauthe S, Vosbeck J, Droeser RA, Bolli M, Peterli R, von Flüe M, Ng CKY, Kollmar O, Coto-Llerena M, Piscuoglio S. Front Oncol. 2022 Jan 10;11:781833. https://www.frontiersin.org/articles/10.3389/fonc.2021.781833/full |
| Suppression of caspase 8 activity by a coronin 1-PI3Kδ pathway promotes T cell survival independently of TCR and IL-7 signaling. Mori M, Ruer-Laventie J, Duchemin W, Demougin P, Ndinyanka Fabrice T, Wymann MP, Pieters J. Sci Signal. 2021 Dec 21;14(714):eabj0057. https://www.science.org/doi/10.1126/scisignal.abj0057?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed |
| Emergence and function of cortical offset responses in sound termination detection. Solyga M, Barkat TR. eLife. 10:e72240. https://elifesciences.org/articles/72240 |
| Task-induced modulations of neuronal activity along the auditory pathway. De Franceschi G, Barkat TR. Cell Reports. Reports 37, 11015. https://www.sciencedirect.com/science/article/pii/S2211124721016090?via%3Dihub |
| Case Report: Reconstruction of a Large Maxillary Defect with an Engineered, Vascularized, Prefabricated Bone Graft. Ismail T, Haumer A, Lunger A, Osinga R, Kaempfen A, Saxer F, Wixmerten A, Miot S, Thieringer F, Beinemann J, Kunz C, Jaquiéry C, Weikert T, Kaul F, Scherberich A, Schaefer DJ, Martin I. Front Oncol. 11: 775136 (2021). https://www.frontiersin.org/articles/10.3389/fonc.2021.775136/full |
| SMAD4 target genes are part of a transcriptional network that integrates the response to BMP and SHH signaling during early limb bud patterning. Gamart J, Barozzi I, Laurent F, Reinhardt R, Martins LR, Oberholzer T, Visel A, Zeller R, Zuniga A. Development. 148, dev200182. https://journals.biologists.com/dev/article/148/23/dev200182/273622/SMAD4-target-genes-are-part-of-a-transcriptional |
| RBFOX splicing factors contribute to a broad but selective recapitulation of peripheral tissue splicing patterns in the thymus. Jansen K, Shikama-Dorn N, Attar M, Maio S, Lopopolo M, Buck D, Holländer GA, Sansom SN. Genome Res. 2021 Nov;31(11):2022-2034. https://genome.cshlp.org/content/31/11/2022.long |
| NOX1 mediates metabolic heart disease in mice and is upregulated in monocytes of humans with diastolic dysfunction. Xu L, Balzarolo M, Robinson EL, Lorenz V, Verde GD, Joray L, Mochizuki M, Kaufmann BA, Valstar G, de Jager SCA, den Ruijter HM, Heymans S, Pfister O, Kuster GM. Cardiovasc Res. 2021 Nov 26;cvab349. https://academic.oup.com/cardiovascres/advance-article/doi/10.1093/cvr/cvab349/6443118?login=true |
| Supervised learning based on tumor imaging and biopsy transcriptomics predicts response of hepatocellular carcinoma to transarterial chemoembolization. Boldanova T, Fucile G, Vosshenrich J, Suslov A, Ercan C, Coto-Llerena M, Terracciano LM, Zech CJ, Boll DT, Wieland S, Heim MH. Cell Rep Med. 2021 Nov 16;2(11):100444. https://www.sciencedirect.com/science/article/pii/S2666379121003128?via=ihub |
| Chronic inflammation and extracellular matrix-specific autoimmunity following inadvertent periarticular influenza vaccination. Hirsiger JR, Tamborrini G, Harder D, Bantug GR, Hoenger G, Recher M, Marx C, Li QZ, Martin I, Hess C, Scherberich A, Daikeler T, Berger CT. J Autoimmun. 2021 Nov;124:102714. https://www.sciencedirect.com/science/article/pii/S0896841121001220?via%3Dihub |
| Nose to Spine: spheroids generated by human nasal chondrocytes for scaffold-free nucleus pulposus augmentation. Gryadunova A, Kasamkattil J, Gay MHP, Dasen B, Pelttari K, Mironov V, Martin I, Schären S, Barbero A, Krupkova O, Mehrkens A. Acta Biomater. 134: 240-251 (2021). https://www.sciencedirect.com/science/article/pii/S174270612100502X?via%3Dihub |
| The Genomic Landscape of Serrated Lesion of the Colorectum: Similarities and Differences With Tubular and Tubulovillous Adenomas. Tornillo L, Lehmann FS, Garofoli A, Paradiso V, Ng CKY, Piscuoglio S. Front Oncol. 2021 Oct 12;11:668466. https://www.frontiersin.org/articles/10.3389/fonc.2021.668466/full |
| Ubiquitous expression of HBsAg from integrated HBV DNA in patients with low viral load. Meier MA, Calabrese D, Suslov A, Terracciano LM, Heim MH, Wieland S. J Hepatol. 2021 Oct;75(4):840-847. https://www.sciencedirect.com/science/article/pii/S0168827821003287?via=ihub |
| Engineering of fully humanized and vascularized 3D bone marrow niches sustaining undifferentiated human cord blood hematopoietic stem and progenitor cells. Born G, Nikolova M, Scherberich A, Treutlein B, García-García A, Martin I. J Tissue Eng. 12: 1-11 (2021). https://journals.sagepub.com/doi/10.1177/20417314211044855?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed |
| Culturing patient-derived malignant hematopoietic stem cells in engineered and fully humanized 3D niches. García-García A, Klein T, Born G, Hilpert M, Scherberich A, Lengerke C, Skoda RC, Bourgine PE, Martin I. Proc Nat Acad Sci USA. 118(40), e2114227118: 1-10 (2021). https://www.pnas.org/doi/10.1073/pnas.2114227118?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed |
| Spatial regulation by multiple Gremlin1 enhancers provides digit development with cis-regulatory robustness and evolutionary plasticity. Malkmus J, Ramos Martins L, Jhanwar S, Kircher B, Palacio V, Sheth R, Leal F, Duchesne A, Lopez-Rios J, Peterson KA, Reinhardt R, Onimaru K, Cohn MJ, Zuniga A, Zeller R. Nature Commun 12, 5557. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455560/ |
| Whole-genome sequence-informed MALDI-TOF MS diagnostics reveal importance of Klebsiella oxytoca group in invasive infections: a retrospective clinical study. Cuénod A, Wüthrich D, Seth-Smith HMB, Ott C, Gehringer C, Foucault F, Mouchet R, Kassim A, Revathi G, Vogt DR, von Felten S, Bassetti S, Tschudin- Sutter S, Hettich T, Schlotterbeck G, Homberger C, Casanova C, Moran-Gilad J, Sagi O, Rodríguez-Sánchez B, Müller F, Aerni M, Gaia V, van Dessel H, Kampinga GA, Müller C, Daubenberger C, Pflüger V, Egli A. Genome Med 2021 Sep 13;13(1):150. https://genomemedicine.biomedcentral.com/articles/10.1186/s13073-021-00960-5 |
| Conserved and species-specific chromatin remodelling and regulatory dynamics during mouse and chicken limb bud development. Jhanwar S, Malkmus J, Stolte J, Romashkina O, Zuniga A, Zeller R. Nature Commun. 12, 5685. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479071/ |
| Systemic identification of novel cancer genes through analysis of deep shRNA perturbation screens. Montazeri H, Coto-Llerena M, Bianco G, Zangene E, Taha-Mehlitz S, Paradiso V, Srivatsa S, de Weck A, Roma G, Lanzafame M, Bolli M, Beerenwinkel N, von Flüe M, Terracciano LM, Piscuoglio S, Ng CKY. Nucleic Acids Res. 2021 Sep 7;49(15):8488-8504. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421231/ |
| Manufacturing of Human Tissues as off-the-Shelf Grafts Programmed to Induce Regeneration. Pigeot S, Klein T, Gullotta F, Dupard SJ, Garcia Garcia A, García-García A, Prithiviraj S, Lorenzo P, Filippi M, Jaquiery C, Kouba L, Asnaghi MA, Raina DB, Dasen B, Isaksson H, Önnerfjord P, Tägil M, Bondanza A, Martin I, Bourgine PE. Adv Mater. 33, 2103737: 1-13 (2021). https://onlinelibrary.wiley.com/doi/10.1002/adma.202103737 |
| Dual targeting of JAK2 and ERK interferes with the myeloproliferative neoplasm clone and enhances therapeutic efficacy. Brkic S, Stivala S, Santopolo A, Szybinski J, Jungius S, Passweg JR, Tsakiris D, Dirnhofer S, Hutter G, Leonards K, Lischer HEL, Dettmer MS, Neel BG, Levine RL, Meyer SC. Leukemia. 2021 Oct;35(10):2875-2884. https://www.nature.com/articles/s41375-021-01391-2 |
| Engineered nasal cartilage for the repair of osteoarthritic knee cartilage defects. Acevedo Rua L, Mumme M, Manferdini C, Darwiche S, Khalil A, Hilpert M, Buchner DA, Lisignoli G, Occhetta P, von Rechenberg B, Haug M, Schaefer DJ, Jakob M, Caplan A, Martin I, Barbero A, Pelttari K. Sci Transl Med. 13(609), eaaz4499:1-14 (2021). https://www.science.org/doi/10.1126/scitranslmed.aaz4499?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed |
| Persistent RNA virus infection is short-lived at the single-cell level but leaves transcriptomic footprints. Reuther P, Martin K, Kreutzfeldt M, Ciancaglini M, Geier F, Calabrese D, Merkler D, Pinschewer DD. J Exp Med. (2021) 218 (10): e20210408. https://rupress.org/jem/article/218/10/e20210408/212556/Persistent-RNA-virus-infection-is-short-lived-at |
| Interferon lambda 4 impairs hepatitis C viral antigen presentation and attenuates T cell responses. Chen Q, Coto-Llerena M, Suslov A, Teixeira RD, Fofana I, Nuciforo S, Hofmann M, Thimme R, Hensel N, Lohmann V, Ng CKY, Rosenberger G, Wieland S, Heim MH. Nat Commun. 2021 Aug 12;12(1):4882. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360984/ |
| Thymus extracellular matrix-derived scaffolds support graft-resident thymopoesis and long-term in vitro culure of adult thymic epithelial cells. Asnaghi MA, Barthlott T, Gullotta F, Strusi V, Amovilli A, Hafen K, Srivastava G, Oertle P, Toni R, Wendt D, Holländer GA, Martin I. Adv Funct Mater 31(20):2010747 (1-15) (2021). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8436951/ |
| Deep learning enables the automation of grading histological tissue engineered cartilage images for quality control standardization. Power L, Acevedo L, Yamashita R, Rubin D, Martin I, Barbero A. Osteoarthritis Cartilage. 29:433-443 (2021). https://www.sciencedirect.com/science/article/pii/S1063458421000042?via%3Dihub |
| Mass Cytometry of CSF Identifies an MS-Associated B-cell Population. Johansson D, Rauld C, Roux J, Regairaz C, Galli E, Callegari I, Raad L, Waldt A, Cuttat R, Roma G, Diebold M, Becher B, Kuhle J, Derfuss T, Carballido JM, Sanderson NSR. Neurol Neuroimmunol Neuroinflamm. 2021 Feb 15;8(2):e943. https://nn.neurology.org/content/8/2/e943.long |
| Adenylosuccinate lyase is oncogenic in colorectal cancer by causing mitochondrial dysfunction and independent activation of NRF2 and mTOR-MYC-axis. Taha-Mehlitz S, Bianco G, Coto-Llerena M, Kancherla V, Bantug GR, Gallon J, Ercan C, Panebianco F, Eppenberger-Castori S, von Strauss M, Staubli S, Bolli M, Peterli R, Matter MS, Terracciano LM, von Flüe M, Ng CKY, Soysal SD, Kollmar O, Piscuoglio S. Theranostics. 2021 Feb 15;11(9):4011-4029. https://www.thno.org/v11p4011.htm |
| Presence of SARS-CoV-2 transcripts in the choroid plexus independent of multiple sclerosis. Fuchs V, Kutza M, Wischnewski S, Deigendesch N, Lutz L, Kulsvehagen L, Ricken G, Kappos L, Tzankov A, Hametner S, Frank S, Schirmer L, Pröbstel AK. Neurol Neuroimmunol Neuroinflamm. 2021; 8(2):e957. https://nn.neurology.org/content/8/2/e957.long |