Selected Publications

Khalil, M, Pirpamer L, Hofer E, Voortman MM, Barro C, Leppert D, Benkert P, Ropele S, Enzinger C, Fazekas F, Schmidt R, Kuhle J. (2020. Serum neurofilament light levels in normal aging and their association with morphologic brain changes. Nat. Commun., 11, 812.

Kuhle J, Kropshofer H, Haering DA, Kundu U, Meinert R, Barro C, Dahlke F, Tomic D, Leppert D, Kappos l. (2019). Blood neurofilament light chain as a biomarker of MS disease activity and treatment response. Neurology 92, E1007–E1015.

Khalil M, Teunissen CE, Otto M, Piehl F, Sormani MP, Gattringer T, Barro C, Kappos L, Comabella M, Fazekas F, Petzold A, Blennow K, Zetterberg H, Kuhle J. (2018). Neurofilaments as biomarkers in neurological disorders. Nat. Rev. Neurol. 14, 577–589.

Barro C, Benkert P, Disanto G, Tsagkas C, Amann M, Naegelin Y, Leppert D, Gobbi C, Granziera C, Yaldizli Ö, Michalak Z, Wuerfel J, Kappos L, Parmar K, Kuhle J. (2018) Serum neurofilament as a predictor of disease worsening and brain and spinal cord atrophy in multiple sclerosis. Brain 141,2382–2391.

Disanto G, Barro C, Benkert P, Naegelin Y, Schädelin S, Giardiello A, Zecca C, Blennow K, Zetterberg H, Leppert D, Kappos L, Gobbi C, Kuhle J. (2017). Serum Neurofilament light: A biomarker of neuronal da-mage in multiple sclerosis. Ann Neurol. 81, 857–870.

Zimmermann M, Rose N, Lindner JM, Kim H, Gonçalves AR, Callegari I, Syedbasha M, Kaufmann L, Egli A, Lindberg RLP, Kappos L, Traggiai E, Sanderson NSR, Derfuss T. (2019). Antigen Extraction and B Cell Activation Enable Identification of Rare Mem-brane Antigen Specific Human B Cells. Front. Immunol. 10, 829.

Naegelin Y, Naegelin P, von Felten S, Lorscheider J, Sonder J, Uitdehaag BMJ, Scotti B, Zecca C, Gobbi C, Kappos L, Derfuss T. (2019). Association of Rituximab Treatment With Disability Progression Among Patients With Secondary Progressive Multiple Sclerosis. JAMA Neurol. 76, 274–281.

Diebold M, Sievers C, Bantug G, Sanderson N, Kappos L, Kuhle J, Lindberg RLP, Derfuss T. (2018). Dimethyl fumarate influences innate and adaptive immunity in multiple sclerosis. J. Autoimmun. 86, 39–50.

Sanderson NS, Zimmermann M, Eilinger L, Gubser C, Schaeren-Wiemers N, Lindberg RL, Dougan SK, Ploegh HL, Kappos L, Derfuss, T. (2017). Cocapture of cognate and bystander antigens can activate autoreactive B cells. Proc. Natl. Acad. Sci. U SA. 114, 734–739.

Pröbstel AK, Kuhle J, Lecourt AC, Vock I, Sanderson NS, Kappos L, Derfuss T. (2016). Multiple Sclerosis and Antibodies against KIR4.1. N. Engl. J. Med. 374, 1496–1498.