Selected Publications
Microglia-Centered Combinatorial Strate-gies Against Glioblastoma. Martins TA, Schmassmann P, Shekarian T, Boulay JL, Ritz MF, Zanganeh S, Vom Berg J and Hutter G (2020). Front Immunol 11, 571951.
Quantitative proteomics reveals reduction of endocytic machinery components in gliomas.Buser DP, Ritz MF, Moes S, Tostado C, Frank S, Spiess M, Mariani L, Jenö P, Boulay JL, Hutter G.EBioMedicine. 2019 Aug;46:32-41. doi: 10.1016/j.ebiom.2019.07.039. Epub 2019 Jul 19.
Microglia are effector cells of CD47-SIRPα antiphagocytic axis disruption against glioblastoma. Hutter G, Theruvath J, Graef CM, Zhang M, Schoen MK, Manz EM, Bennett ML, Olson A, Azad TD, Sinha R, Chan C, Assad Kahn S, Gholamin S, Wilson C, Grant G, He J, Weissman IL, Mitra SS, Cheshier SH. Proc Natl Acad Sci U S A. 2019 Jan 2. pii: 201721434. doi: 10.1073/pnas.1721434116. [Epub ahead of print]
Tumor-associated macrophages, nanomedicine and imaging: the axis of success in the future of cancer immunotherapy. Zanganeh S, Spitler R, Hutter G, Ho JQ, Pauliah M, Mahmoudi M. Immunotherapy. 2017 Sep;9(10):819-835. doi: 10.2217/imt-2017-0041.
PD-1 expression by tumour-associated macrophages inhibits phagocytosis and tumour immunity. Gordon SR, Maute RL, Dulken BW, Hutter G, George BM, McCracken MN, Gupta R, Tsai JM, Sinha R, Corey D, Ring AM, Connolly AJ, Weissman IL.Nature. 2017 May 25;545(7655):495-499. doi: 10.1038/nature22396. Epub 2017 May 17.
Disrupting the CD47-SIRPα anti-phagocytic axis by a humanized anti-CD47 antibody is an efficacious treatment for malignant pediatric brain tumors. Gholamin S, Mitra SS, Feroze AH, Liu J, Kahn SA, Zhang M, Esparza R, Richard C, Ramaswamy V, Remke M, Volkmer AK, Willingham S, Ponnuswami A, McCarty A, Lovelace P, Storm TA, Schubert S, Hutter G, Narayanan C, Chu P, Raabe EH, Harsh G 4th, Taylor MD, Monje M, Cho YJ, Majeti R, Volkmer JP, Fisher PG, Grant G, Steinberg GK, Vogel H, Edwards M, Weissman IL, Cheshier SH. Sci Transl Med. 2017 Mar 15;9(381). pii: eaaf2968. doi: 10.1126/scitranslmed.aaf2968.
Reverse phase protein arrays enable glioblastoma molecular subtyping. Hutter G, Sailer M, Azad TD, von Bueren AO, Nollau P, Frank S, Tostado C, Sarvepalli D, Ghosh A, Ritz MF, Boulay JL, Mariani L. J Neurooncol. 2017 Feb;131(3):437-448. doi: 10.1007/s11060-016-2316-5. Epub 2016 Nov 17.
Iron oxide nanoparticles inhibit tumour growth by inducing pro-inflammatory macrophage polarization in tumour tissues. Zanganeh S, Hutter G, Spitler R, Lenkov O, Mahmoudi M, Shaw A, Pajarinen JS, Nejadnik H, Goodman S, Moseley M, Coussens LM, Daldrup-Link HE. Nat Nanotechnol. 2016 Nov;11(11):986-994. doi: 10.1038/nnano.2016.168. Epub 2016 Sep 26.
An Enzyme- and Serum-free Neural Stem Cell Culture Model for EMT Investigation Suited for Drug Discovery. Sailer MH, Sarvepalli D, Brégère C, Fisch U, Guentchev M, Weller M, Guzman R, Bettler B, Ghosh A, Hutter G. J Vis Exp. 2016 Aug 23;(114). doi: 10.3791/54018.
Anti-CD47 Treatment Stimulates Phagocytosis of Glioblastoma by M1 and M2 Polarized Macrophages and Promotes M1 Polarized Macrophages In Vivo. Zhang M, Hutter G, Kahn SA, Azad TD, Gholamin S, Xu CY, Liu J, Achrol AS, Richard C, Sommerkamp P, Schoen MK, McCracken MN, Majeti R, Weissman I, Mitra SS, Cheshier SH. PLoS One. 2016 Apr 19;11(4):e0153550. doi: 10.1371/journal.pone.0153550. eCollection 2016.
Intracranial Interdigitating Dendritic Cell Sarcoma: First Case Report. Hutter G, Hofer S, Tzankov A, Kothbauer KF. Neurosurgery. 2015 Dec;77(6):E979-83. doi: 10.1227/NEU.0000000000000925.
SIRPα polymorphisms, but not the prion protein, control phagocytosis of apoptotic cells. Nuvolone M, Kana V, Hutter G, Sakata D, Mortin-Toth SM, Russo G, Danska JS, Aguzzi A. J Exp Med. 2013 Nov 18;210(12):2539-52. doi: 10.1084/jem.20131274. Epub 2013 Oct 21.