Journal Club: American Society of Transplantation - Speaker Caroline A. Hillenbrand (Hirsch Lab)

We are excited to announce an upcoming AST Journal Club webinar featuring Caroline A. Hillenbrand, PhD student in the Hirsch Research Group (Transplantation & Clinical Virology). Hosted by AST's Infectious Disease Community of Practice (IDCOP).

Join us to discuss the article: BK Polyomavirus (BKPyV) Serotype-Specific Antibody Responses in Blood Donors and Kidney Transplant Recipients with and without new-onset BKPyV-DNAemia: A Swiss Transplant Cohort Study

11.00am – 12.00pm ET

REGISTER for Webinar

In this featured American Journal of Transplantation (AJT) article:
BK polyomavirus (BKPyV) causes premature renal failure in 10% to 30% of kidney transplant recipients (KTRs). Current guidelines recommend screening for new-onset BKPyV-DNAemia/nephropathy and reducing immunosuppression to regain BKPyV-specific immune control. Because BKPyV encompasses 4 major genotype (gt)-encoded serotypes (st1,-2,-3,-4), st-specific antibodies may inform the risk and course of BKPyV-DNAemia/nephropathy. [The authors] analyzed plasma from 399 blood donors (BDs) and 428 KTRs (134 KTR-cases with BKPyV-DNAemia, 294 KTR-controls)... [and found] BKPyV st-specific antibody levels at transplantation might reflect gt/st-BKPyV-specific immunity clearing or preventing BKPyV-DNAemia in KTR-cases or KTR-controls, respectively. Accordingly, active or passive immunization may be most efficient pretransplant or early posttransplant. Read more

This AST Journal Club Series webinar is hosted by AST's Infectious Disease Community of Practice (IDCOP). All AST Journal Clubs are free but registration is required to attend live. To learn more about the American Journal of Transplantation (AJT), visit www.amjtransplant.org.

All AST Journal Clubs are free, but registration is required to attend live. Can't make the live Journal Club? Register now, and you'll be notified when the archive is available.

Export event as iCal