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An engineered microenvironment couples angiogenesis and osteogenesis for bone regeneration (Banfi Lab)
In this manuscript we find that controlling the dose distribution of VEGF protein in an osteogenic graft is key to maintaining the physiological coupling of angiogenesis and osteogenesis that is required for effective bone regeneration.
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A coat of fat and sugar helps cancer cells to spread (Heinzelmann Lab)
Changes to tumor cells during metastasis depend on certain molecules on the cell surface. Here, the importance of “glycolipids” in the spread of ovarian cancer has been deciphered by a Basel-led international team. These findings could pave…
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Congratulations to Prof. Dr. Anne-Katrin Pröbstel for receiving the Sobek Young Investigator Award 2022
Due to the pandemic, the Roman, Marga and Mareille Sobek Foundation honored its prize winners from 2020 to 2022 in a joint ceremony at the Stuttgart Music Academy.
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Interferon-γ resistance and immune evasion in glioma develop via Notch-regulated co-evolution of malignant and immune cells (Taylor Lab)
Gliomas are aggressive brain tumors and resistant to current standard and targeted therapeutic interventions. Immune evasion is pronounced in glioma, but the underlying mechanisms remain poorly understood. Parmigiani et al. demonstrate that…