News
Autoimmunkrankheiten: Basel ist wichtiger Partner bei grosser europäischer Forschungsoffensive
Autoimmune, entzündliche und allergische Erkrankungen sind verbreitete chronische Erkrankungen, die das Leben von Millionen Menschen in aller Welt beeinträchtigen. Sie sind auch ein signifikanter Faktor bei den Gesundheitskosten. Nun will…
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Members of the Zippelius lab and collaborators revealed how microtubule destabilitzing chemotherapy promotes protective anti-tumor immunity.
In collaboration with researchers from Massachusetts General Hospital and Harvard Medical School, Abhishek Kashyap and colleagues found that microtubule destabilization in dendritic cells results in the release of the guanine nucleotide…
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The Hess and Recher labs identify the disease mechanism of a hitherto unknown primary antibody defciency
The researchers identified a gain-of-function mutation in the metabolic enzyme SDHA, which leads to an accumulation of fumarate and causes inflamatory mitochondrial retrograde signaling as a disease modifier in primary antibody…
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Verdon Taylor and collaborators identified a signalling pathway that maintains neural stem cell quiescence in adult mouse brain
In their study that was recently published in Cell Reports they discovered a central role fot the Notch2 effector Id4. Id4 not only blocks cell cycle entry but also promotes astrocytic differentiation of hippocampal neural stem cells. …