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The Hess and Recher labs identify the disease mechanism of a hitherto unknown primary antibody defciency
The researchers identified a gain-of-function mutation in the metabolic enzyme SDHA, which leads to an accumulation of fumarate and causes inflamatory mitochondrial retrograde signaling as a disease modifier in primary antibody…
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Verdon Taylor and collaborators identified a signalling pathway that maintains neural stem cell quiescence in adult mouse brain
In their study that was recently published in Cell Reports they discovered a central role fot the Notch2 effector Id4. Id4 not only blocks cell cycle entry but also promotes astrocytic differentiation of hippocampal neural stem cells. …
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Nina Khanna Gremmelmaier receives the 2019 research prize by the city of Basel
The DBM congratulates Nina Khanna Gremmelmaier, research group leader of the Infection Biology lab, to this acheivement! Official press release Uninews BZ Nau.ch
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Claudia Lengerke and collaborators discovered how Leukaemia Stem Cells develop resistance against immune cells and suggest novel treatment strategies for patients
The Lengerke Lab elucidated how Leukaemia Stem Cells evade the attack by Natural Killer cells and suggest novel strategies for therapy. Their findings have recently been published in Nature. Uninews