05 Jun 2018 / Research

In a collaborative effort scientists from the DBM (Martin, Skoda and Lengerke labs) and from ETH Zürich (Schroeder lab at D-BSSE) have engineered an artificial bone marrow niche.

The study was supported by the StemSysMed SystemsX grant (link) and was published recently in PNAS. The findings open up new possibilities from basic research on blood formation in humans to the development of diagnostic tools for…

09 May 2018 / Research

Researchers from the De Libero Group discovered how MAIT cells, specific immune cells in the gut, sense the metabolic state of enteric bacteria.

Their study, which was recently published in the Journal Mucosal Immunology, shows that the colon environment contributes to mucosal immunosurveillance by directly affecting bacterial metabolism, and indirectly controlling MAIT cell…

17 Apr 2018 / Research

Mimicking the molecular processes occurring during embryonic cartilage formation, researchers from the Martin Group succeeded in “developmentally engineering” cartilage tissue from adult human mesenchymal stromal cells.

Their findings were recently published in PNAS. Uninews

16 Apr 2018 / People

The DBM welcomes Prof. Alexander Navarini as new research group leader and Professor of Dermatology.

Prof. Navarini (link) will be the successor of Prof. Peter Itin (link) as Professor of Dermatology and will build up his lab at the DBM as of November 1, 2018.His research focuses on the genetics of neutrophil-mediated dermatoses and on the…

05 Apr 2018 / Research

The Jeker lab has developed an in vivo technique to quickly and reliably edit primary T cells.

Using this method, they were able to repair a mutation in the FOXP3 gene that causes severe autoimmune diseases in mice. The findings have been published in The Journal of Immunology and also open up new perspectives for the development of…