News
Jürg Schwaller and collaborators explain why some forms of leukemia develop only in infants. (Journal of Cancer Discovery)
Why some forms of leukemia only affect children
Autoimmunkrankheiten: Basel ist wichtiger Partner bei grosser europäischer Forschungsoffensive
Autoimmune, entzündliche und allergische Erkrankungen sind verbreitete chronische Erkrankungen, die das Leben von Millionen Menschen in aller Welt beeinträchtigen. Sie sind auch ein signifikanter Faktor bei den Gesundheitskosten. Nun will…
/ News, Research
Members of the Zippelius lab and collaborators revealed how microtubule destabilitzing chemotherapy promotes protective anti-tumor immunity.
In collaboration with researchers from Massachusetts General Hospital and Harvard Medical School, Abhishek Kashyap and colleagues found that microtubule destabilization in dendritic cells results in the release of the guanine nucleotide…
/ News, Research
The Hess and Recher labs identify the disease mechanism of a hitherto unknown primary antibody defciency
The researchers identified a gain-of-function mutation in the metabolic enzyme SDHA, which leads to an accumulation of fumarate and causes inflamatory mitochondrial retrograde signaling as a disease modifier in primary antibody…