Jonas Lötscher, Adrià-Arnau Martí i Líndez, Nicole Kirchhammer, Elisabetta Cribioli, Greta Giordano, Marcel P. Trefny, Markus Lenz, Sacha I. Rothschild, Paolo Strati, Marco Künzli, Claudia Lotter, Susanne H. Schenk, Philippe Dehio, Jordan Löliger, Ludivine Litzler, David Schreiner, Victoria Koch, Nicolas Page, Dahye Lee, Jasmin Grählert, Dmitry Kuzmin, Anne-Valérie Burgener, Doron Merkler, Miklos Pless, Maria L. Balmer, Walter Reith, Jörg Huwyler, Melita Irving, Carolyn G. King, Alfred Zippelius, Christoph Hess. Magnesium sensing via LFA-1 regulates CD8+ T cell effector function, Cell, 2022, In Press
Balmer M. L., R. Epple, E. H. Ma, A. Egli, L. Bubendorf, K. Rentsch, A.-K. Woischnig, N. KhannaJ. Loeliger, J. Loetscher, P. Dehio, G. Perrin, J. D. Warncke, O. P. Schären, C. M. Schürch, G. Unterstab, A. Thompson, S. Hapfelmeier, R. G. Jones, C. Hess. Memory CD8+ T cells balance pro- and anti-inflammatory activity by reprogramming cellular acetate handling at sites of infection. Cell Metabolism 2020. 32: 457-467.
Dimeloe S., P. Gubser, J. Loeliger, C. Frick, L. Develioglu, M. Fischer, F. Marquardsen, G. R. Bantug, D. Thommen, Y. Lecoultre, A. Zippelius, A. Langenkamp, C. Hess. Tumor-derived TGF-β inhibits mitochondrial respiration to suppress IFN-γ production by human CD4+ T cells. Sci Signal. 2019 Sep 17;12(599):eaav3334.
Burgener A.-V., G. R. Bantug, B. Meyer, R. Higgins, A. Ghosh, O. Bignucolo, E. H. Ma, J. Löliger, G. Unterstab, M. Geigges, R. Steiner, M. Enamorado, R. Ivanek, D. Hunziker, A. Schmidt, B. Müller-Durovic, J. Grählert, R. Epple, S. Dimeloe, J. Lötscher, U. Sauder, M. Ebnöther, B. Burger, I. Heijnen, S. Martínez-Cano, N. Cantoni, R. Brücker, C. R. Kahlert, D. Sancho, R. G. Jones, A. Navarini, M. Recher, C. Hess. SDHA gain-of-function engages inflammatory mitochondrial retrograde signaling via KEAP1–Nrf2. Nature Immunology 2019. 20, 1311-1321.
Rao T. N., N. Hansen, J. Hilfiker, S. Rai, J.-M. Majewska, T. Kassel, F. Geier, J. Delezie, R. Nienhold, H. H. Shen, C. Beisel, S. Di Palma, J. Trebicka, D. Wolf, M. Gassmann, T. W.-M. Fan, C. Handschin, S. Dirnhofer, N. Kröger, C. Hess, T. Radimerski, R. C. Skoda. JAK2 mutant hematopoietic cells display metabolic alterations that can be targeted to treat myeloproliferative neoplasms. Blood 2019 Nov 21; 134(21): 1832–1846.
Ishay-Ronen D., M. Diepenbruck, R. K. R. Kalathur, N. Sugiyama, S. Tiede, R. Ivanek, G. Bantug, M. Francesco Morini, J. Wang, C. Hess, G. Christofori. Gain Fat–Lose Metastasis: Converting Invasive Breast Cancer Cells into Adipocytes Inhibits Cancer Metastasis. Cancer Cell 2019. 14:17-32.
Müller-Durovic B., J. Grählert, O. Devine, A. N. Akbar, C. Hess. CD56-negative NK cells with impaired effector function expand in CMV and EBV co-infected healthy donors with age. Aging 2019. 11:724-740.
Quteineh L., A. Wójtowicz, P.-Y. Bochud, S. Crettol, F. Vandenberghe, J.-P. Venetz, O. Manuel, D. Golshayan, R. Lehmann, N. J. Mueller, I. Binet, C. van Delden, J. Steiger, P. Mohacsi, J.-F. Dufour, P. M Soccal, Z. Kutalik, P. Marques-Vidal, P. Vollenweider, M. Recher, C. Hess, M. Pascual, C. B. Eap. Genetic inflammatory markers associated with diabetes in solid organ transplant recipients. American Journal of Transplantation 2019. 19:238-246.
Burkard T., M. Trendelenburg, T. Daikeler, C. Hess, J. Bremerich, P. Haaf, P. Buser, M.J. Zellweger. The heart in systemic lupus erythematosus - A comprehensive approach by cardiovascular magnetic resonance tomography. PLoS One 2018. 13:e0202105.
Fischer M., G. R. Bantug, S. Dimeloe, P. M. Gubser, A.-V. Burgener, J. Grählert, M. L. Balmer, L. Develioglu, R. Steiner, G. Unterstab, U. Sauder, G. Hoenger, C. Hess. Early effector maturation of naïve human CD8 T cells requires mitochondrial biogenesis. European Journal of Immunology 2018. 48:1632-1643.
Thommen D.S., V.H. Koelzer, K.D. Mertz, P. Herzig, A. Roller, M. Trefny, S. Dimeloe, A. Kiialainen, J. Hanhart, C. Schill, C. Hess, S.S. Prince, M. Wiese, D. Lardinois, P.-C. Ho, C. Klein, V. Karanikas, T.N. Schumacher, A. Zippelius. A transcriptionally and functionally distinct PD-1+ CD8+ T cell pool with predictive potential in non-small cell lung cancer treated with PD-1 blockade. Nature Medicine 2018. 24:994-1004.
Bantug G., M. Fischer, J. Grählert, M.L. Balmer, G. Unterstab, L. Develioglu, R. Steiner, L. Zhang, A.S. Henriques da Costa, P.M. Gubser, A.-V. Burgener, U. Sauder, J. Löliger, R. Belle, S. Dimeloe, J. Lötscher, A. Jauch, M. Recher, G. Hönger, M.N. Hall, P. Romero, C. Frezza, C. Hess. Mitochondria–ER contact sites are immunometabolic hubs that orchestrate the rapid recall response of memory CD8+ T cells. Immunity 2018. 3:542-555.
Marquardsen F.A, F. Baldin1, F. Wunderer, W. Al-Herz, R. Mikhael, G. Lefranc, Z. Baz, F. Rezaee, R. Hanna, S. Kfir-Erenfeld, P. Stepensky, B. Meyer, A. Jauch, M.B. Bigler, A.-V. Burgener, R. Higgins, A.A. Navarini, J.A. Church, J. Chou, R. Geha, L.D. Notarangelo, C. Hess, C.T. Berger, D.B. Bloch, M. Recher. Detection of Sp110 by flow-cytometry and application to screening patients for veno-occlusive disease with immunodeficiency. Journal of Clinical Immunology 2017. 37:707-714.
Schürmann N., P. Forrer, O. Casse, J. Li, B. Felmy, A.-V. Burgener, N. Ehrenfeuchter, W.-D. Hardt, M. Recher, C. Hess, A. Tschan-Plessl, N. Khanna, D. Bumann. Myeloperoxidase targets oxidative host attacks to pathogens and prevents collateral tissue damage. Nature Microbiology 2017. 2:16268.
Ma E.H., G. Bantug, T. Griss, M.J. Verway, R.M. Johnson, S. Condotta, T.C. Raissi, H. Tsui, B. Samborska, G. Boukhaled, M. Balmer, S. Henriques da Costa, C. Frezza, C.M. Krawczyk, M.J. Richer, C. Hess, R.G. Jones. Serine is an essential metabolite for effector T cell expansion. Cell Metabolism 2017. 2:345-357.
Navarini A.A., P. Hruz, C.T. Berger, T. Hou, C. Schwab, A. Gabrysch, R. Higgins, N. Frede, B.-C. Padberg Sgier, O. Kämpe, A.-V. Burgener, F. Marquardsen, F. Baldin, M. Bigler, A. Kistner, A. Jauch, O. Bignucolo, B. Meyer, F. Meienberg, M. Mehling, L.T. Jeker, I.A.F.M. Heijnen, T. Daikeler, J.-O. Gebbers, B. Grimbacher*, D. Sansom*, R. Jeker*, C. Hess*, M. Recher* (* equal contribution). Vedolizumab as a successful treatment of CTLA-4 associated autoimmune enterocolitis. Journal of Allergy and Clinical Immunology 2017. 139:1043-1046.
Li Q, W. Bu, E. Gabriel, F. Aguilar, Y. Hoshino, H. Miyadera, C. Hess, R.L. Hornung, A. Roy and J.I. Cohen. HLA-DQ β1 alleles associated with Epstein-Barr virus (EBV) infectivity and EBV gp42 binding to cells. Journal of Clinical Investigation - Insight 2017. 2:e85687.
Balmer M.L., E.H. Ma, G.R. Bantug, J. Grählert, S. Pfister, T. Glatter, A. Jauch, S. Dimeloe, E. Slack, P. Dehio, M.A. Krzyzaniak, C.G. King, A.-V. Burgener, M. Fischer, L. Develioglu, R. Belle, M. Recher, W.V. Bonilla, A.J. Macpherson, S. Hapfelmeier, R.G. Jones, C. Hess. Memory CD8+ T Cells Require Increased Concentrations of Acetate Induced by Stress for Optimal Function, Immunity 2016. 44:1312-1324.
Pisarsky L, R. Bill, E. Fagiani, S. Dimeloe, R.W. Goosen, J. Hagmann, C. Hess, G. Christofori. Targeting metabolic symbiosis to overcome resistance to anti-angiogenic therapy, Cell Reports 2016. 15:1161-1174.
Recher M, C.T. Berger, T. Daikeler, C. Hess, I.A.F.M. Heijnen. A ‘Too Negative’ ANA Test Predicts Antibody Deficiency, Clinical Immunology 2016. 36:374-6.
Dimeloe S., M. Mehling, C. Frick, J. Loeliger, G. R. Bantug, U. Sauders, M. Fischer, R. Belle, L. Develioglu, S. Tay, A. Langenkamp, C. Hess. The Immune-Metabolic Basis of Effector Memory CD4+ T Cell Function under Hypoxic Conditions, Journal of Immunology 2016. 196:106-14.
Bigler M., S.B. Egli, C. Hysek, G. Hoenger, M. Recher, M. Liechti, C. Hess, C.T. Berger. Stress-induced in vivo recruitment of human cytotoxic Natural Killer cells is epinephrine-mediated and requires distinct receptor profiles, PLoS ONE 2015 10(12): e0145635.
Schmied L., G. Terszowski, A. Gonzalez, K. Schmitter, H.H. Hirsch, C. Garzoni, C. van Delden, K. Boggian, N.J. Mueller, C. Berger, J. Villard, O. Manuel, P. Meylan, C. Hess, M. Stern. Protection from varicella zoster in solid organ transplant recipients carrying KIR B haplotypes, Transplantation 2015. 99:2651-5.
Nowakowska J., C. Stuehler, A. Egli, M. Battegay, G. Rauser, G.R. Bantug, C. Brander, C. Hess, N. Khanna. T cells specific for different latent and lytic viral proteins efficiently control Epstein-Barr virus-transformed B cells, Cytotherapy 2015. 17:1280-91.
Mehling M., A.-V. Burgener, V. Brinkmann, G.R. Bantug, S. Dimeloe, G. Hoenger, L. Kappos, C. Hess. Tissue distribution dynamics of human NK cells inferred from peripheral blood depletion kinetics after sphingosine-1-phosphate receptor blockade, Scandinavian Journal of Immunology 2015. 82:460-6.
Marschall K., M. Hoernes, M. Bitzenhofer-Grüber, P. Jandus, A. Duppenthaler, A. Wuillemin, J. Rischewski, O. Boyman, U. Heininger, T. Hauser, U. Steiner, C. Posfay-Barbe, J. Seebach, M. Recher, C. Hess, A. Helbling, J. Reichenbach. The Swiss National Registry for Primary Immunodeficiencies: Report of the first 6 years activity 2008-2014, Clinical and Experimental Immunology 2015. 182:45-50.
Kolev M., S. Dimeloe, G. Le Friec, A. Navarini, G. Arbore, G.A. Povoleri, M. Fischer, R. Belle, J. Loeliger, L. Develioglu, G.R. Bantug, J. Watson, L. Couzi, B. Afzali, P. Lavender, C. Hess* and Claudia Kemper* (* equal contribution and corresponding author). CD46 links complement and metabolic reprogramming in human Th1 responses, Immunity 2015. 16:1033-47.
Berger C.T., V. Greiff, S. John, K.F. Koenig, M. Bigler, M. Recher, T. Daikeler, C. Hess. Risk factors for pneumocystis jirovecii pneumonia in Giant Cell Arteritis - a single center cohort study, Clinical and Experimental Rheumatology 2015. 33:122-5.
Aschwanden M., S. Imfeld, D. Staub, T. Baldi, U.A. Walker, C.T. Berger, C. Hess, T. Daikeler. The ultrasound compression sign to diagnose temporal giant cell arteritis shows an excellent interobeserver agreement, Clinical and Experimental Rheumatology 2015. 33:113-5.
Berger T.C., V. Greiff, M. Mehling, S. Fritz, M.A. Meier, G. Hoenger, A. Conen, M. Recher, M. Battegay, S.T. Reddy, C. Hess. Influenza vaccine response profiles are affected by vaccine preparation and pre-existing immunity, but not HIV infection. Human Vaccines & Immunotherapeutics 2015. 11:391-6.
Hönger G., N. Krähenbühl, S. Dimeloe, M. Stern, P. Amico, S. Schaub, C. Hess. Inter-individual differences in HLA expression can impact the CDC crossmatch. Tissue Antigens 2015. 85:260-6.
Mehling M., D. Eichin, P. Hafner, G. Hoenger, L. Kappos, C. Hess. Avidity of vaccine-induced influenza IgG fails to increase in fingolimod-treated MS patients. Neurology: Neuroimmunology & Neuroinflammation 2014. 11:1:e28
Dimeloe S., C. Frick, M. Fischer, P.M. Gubser, L. Razik, G.R. Bantug, M. Ravon, A. Langenkamp, C. Hess. Human regulatory T cells lack the cyclophosphamide-extruding transporter ABCB1. European Journal of Immunology 2014. 44:3614-20.
Gonzalez A., K. Schmitter, H.H. Hirsch, C. Garzoni, C. van Delden, K. Boggian, N.J. Mueller, C. Berger, J. Villard, O. Manuel, P. Meylan, M. Stern, C. Hess. KIR-associated protection from CMV replication requires pre-existing immunity; a prospective study in solid organ transplant recipients. Genes and Immunity 2014. 15:495-9.
Recher M., M.-L. Karjalainen-Lindsberg, M. Lindlöf, M. Söderlund-Venermo, G. Lanzi, E. Väisänen, A. Kumar, M. Sadeghi, C.T. Berger, T. Alitalo, P. Anttila, M. Kolehmainen, R. Franssila, T. Chen, S. Siitonen, O.M. Delmonte, J.E. Walter, I. Pessach, C. Hess, M.A. Simpson, A.A. Navarini, S. Giliani, K. Hedman, M. Seppänen, L.D. Notarangelo. Genetic variation in schlafen genes in a patient with a recapitulation of the murine ‘Elektra’ phenotype. Journal of Allergy and Clinical Immunology 2014. 133:1462-5.
Mehling M., S. Fritz, P. Hafner, D. Eichin, T. Yonekawa, T. Klimkait, R.L.P. Lindberg, L. Kappos, C. Hess. Preserved antigen-specific immune response in patients with multiple sclerosis responding to IFNβ-therapy. PLoS ONE 2013. 8: e78532.
Gubser P., G.R. Bantug, L. Razik, M. Fischer, S. Dimeloe, G. Heonger, B. Durovic, A. Jauch, C. Hess. Rapid effector function of memory CD8+ T cells requires an immediate-early glycolytic switch. Nature Immunology 2013. 14:1064-72.
Durovic B, O. Gasser, J. Sigle, H.H. Hirsch, M. Stern, A. Buser, C. Hess. Protection from EBV is associated with HLA-C and HLA-Bw4 variants and tonsillectomy. Journal of Virology 2013 87:6526-9.
Mehling M., V. Brinkmann, A.-V. Burgener, P. Gubser, A.D. Luster, L. Kappos, C. Hess. Lymph node access-hierarchy and homing-frequency of human T cells derived from peripheral blood depletion-kinetics after S1P-receptor blockade. Journal of Allergy and Clinical Immunology 2013 131:1440-3.
Recher M., A. J. Fried, M. Massaad, H. Y. Kim, M. Rizzini, F. Frugoni1, J. E. Walter, D. Mathew, C. Hess, S. Giliani, D. T. Umetsu, L. D. Notarangelo, R. S. Geha. Intronic SH2D1A mutation with impaired SAP expression and agammaglobulinemia. Clinical Immunology 2013 146:84-9.
Gasser O., M. Wolbers, H. Günthard, C. Brander, M. Battegay, C. Hess. Expansion of HIV-specific T cells during successful anti-retroviral therapy. HIV Medicine 2013 14:241-6.
Aschwanden M, T. Daikeler, F. Kesten, T. Baldi, D. Benz, A. Tyndall, D. Staub, C. Hess*, K. Jaeger* (*equal contributors). Temporal Artery-Visibility upon Compression ('Compression-Sign') –a New Ultrasound Criterion for the Diagnosis of Giant Cell Arteritis. European Journal of Ultrasound 2013. 34:47-50.
Stern M., K. Czaja, A. Rauch, M. Rickenbach, H.F. Günthard, M. Battegay, J. Fellay, B. Hirschel, C. Hess. HLA-Bw4 identifies a population of HIV-infected patients with an increased capacity to control viral replication after structured treatment interruption. HIV Medicine 2012 13:589-95.
Henn M. R., C. L. Boutwell, N. J. Lennon, P. Charlebois, K. A. Power, A. M. Berlin, A. R. Macalalad, C. M. Malboeuf, E. M. Ryan, M. Casali, R. L. Erlich, L. M. Green, A. Berical, Y. Wang, M. C. Zody, H. Streeck, S. Gnerre, A. K. Bloom, T. Dudek, K. L. Axten, A. D. Gladden, L. Phillips, M. Kemper, Q. Zeng, T. P. Shea, K. Kane, S. Gujja, C. Zedlack, O. Gasser, C. Brander, C. Hess, H. F. Günthard, Z. Brumme, C. Brumme, S. Bazner, J. Rychert, E. Rosenberg, The International HIV Controllers Study, F. Pereyra, J. Z. Levin, S. K. Young, H. Jessen, M. Altfeld, B. W. Birren, B. D. Walker, T. M. Allen. Whole Genome Deep Sequencing of HIV-1 Reveals the Impact of Early Minor Variants Upon Immune Recognition During Acute Infection. PLoS Pathogens 2012. 8:e1002529.
Holbro A., A. Jauch, D. Lardinois, A. Tzankov, S. Dirnhofer, C. Hess. High prevalence of infections and autoimmunity in patients with thymoma. Human Immunology 2012. 73:287-90.
Stern M., K. Hadaya, G. Hönger, P.-Y. Martin, C. Hess*, Jean Villard* (*equal contributors). Telomeric rather than centromeric activating KIR genes protect from reactivation of cytomegalovirus infection after kidney transplantation. American Journal of Transplantation 2011. 11:1302-7.
Mehling M., P. Hilbert, S. Fritz, B. Durovic, D. Eichin, O. Gasser, J. Kuhle, T. Klimkait, R.L.P. Lindberg, L. Kappos, C. Hess. Antigen-specific adaptive immune responses in fingolimod-treated MS patients. Annals of Neurology 2011. 69:408-13.
Durovic B., G. Zenhaeusern, G. Hoenger, O. Gasser, S. Schaub, C. Hess. Allo-specific IL-6 is identifies a subset of individuals at risk for allograft injury. Scandinavian Journal of Immunology 2011. 73:156-8.
Daikeler T., A. Tzankov, G. Hoenger, O. Gasser, A. Tyndall, A. Gratwohl, C. Hess. Minimal T cell-requirements for triggering hemophagocytosis associated with EBV-driven B cell proliferation; a clinical case-study. Annals of the Rheumatic Diseases 2011. 70:1338-9.
Gasser O., G. Zenhaeusern, G. Hönger, C. Brander, C. Hess. Immunosuppressive drugs asymmetrically impact circulating T cell count and function. Scandinavian Journal of Immunology 2011. 73:76-7.
Daikeler T., G. Hoenger, I. Oehri, A. Tyndall, A. Gratwohl, C. Brander, T. Klimkait, O. Gasser, C. Hess. Dominant Epstein Barr virus-specific T cell responses are maintained during moderate and intense immuno-suppressive treatment. Annals of the Rheumatic Diseases 2011. 70:395-6.
Fritz S., E. Mossdorf, B. Durovic, G. Zenhaeusern, A. Conen, I. Steffen, M. Battegay, R. Nuesch, C. Hess. Virosomal influenza vaccine induces distinct immune responses in HIV-infected individuals with low versus high CD4+ T cell counts; clues towards a rational vaccination strategy. AIDS 2010. 24:2287-9.
Mehling M., R. Lindberg, F. Raulf, J. Kuhle, C. Hess, L. Kappos, V. Brinkmann. FTY720 treatment reduces peripheral TH17 cells in patients with multiple sclerosis. Neurology 2010. 75:403-10.
Stern M., G. Opelz, B. Doehler, C. Hess. Natural Killer Cell Receptor Polymorphisms and Post-Transplant non-Hodgkin Lymphoma. Blood 2010. 13:3960-5.
Kesten F., M. Aschwanden, M. Stern, C. Thalhammer, U.W. Walker, A. Tyndall, K. Jaeger, C. Hess*, T. Daikeler* (*equal contributors). Vascular ultrasound examination of 2x11 arterial regions in patients with suspected giant cell arteritis. Annals of the Rheumatic Diseases 2010. 69:1356-9.
Zenhaeusern G., O. Gasser, G. Hoenger, B. Durovic, M. Stern, C. Hess. HLA C Allotypes Differentially Support Regulatory Allo-Specific NK Cell-Function. American Journal of Transplantation 2009. 9:2624-30.
Schaub S., P. Nickerson, D. Rush, M. Mayr, C. Hess, M. Golian, W. Stefura, K. HayGlass. Urinary CXCL9 and CXCL10 levels correlate with the extent of subclinical Tubulitis. American Journal of Transplantation 2009. 9:1347-53.
Zenhaeusern G., G. Hönger, O. Gasser, J. Steiger, S. Schaub, C. Hess. CD56(bright) Natural Killer Cells Expand and Contract Irrespective from CD25 Antibody-Treatment in Kidney Allograft-Recipients. Scandinavian Journal of Immunology 2009. 69:465-7.
Gasser O., F. Bihl, S. Sanghavi, C. Rinaldo, D. Rowe, C. Hess, D. Stablein, M. Roland, P. Stock, C. Brander. Treatment-dependent loss of polyfunctional CD8+ T-cell responses in HIV-infected kidney transplant recipients is associated with herpesvirus reactivation. American Journal of Transplantation 2009. 9:794-803.
Berger C., M. Wolbers, P. Meyer, T. Daikeler, C. Hess. High incidence of severe ischemic complications in patients with giant cell arteritis irrespective of platelet-count and -size, and platelet inhibition. Rheumatology 2009. 48:258-61.
Holbro A., P. Schütz, C. Hess*, T. Daikeler* (*equal contributors). Lymphocyte-Counts in Patients with ANCA-Associated Vasculitis. Rheumatology International 2009. 29:807-10.
Zenhaeusern G., P. Gubser, O. Gasser, A. Trampuz, A. Steinhuber, A.D. Luster, C. Hess. A ‘High-Mobility Low-Cost’ Phenotype Defines Effector-Memory CD8+ T-cells. Blood 2009. 113:95-99.
Stern M., H. Elsässer, G. Hoenger, J. Steiger, S. Schaub, C. Hess. The number of activating KIR genes inversely correlates with the rate of CMV infection and reactivation in kidney transplant-recipients. American Journal of Transplantation 2008. 8:1312-7.
Daikeler T., S. Regenass, A. Tyndall, M.M. Gencay, M. Roth, M. Christ-Crain, B. Müller, C. Hess. Increased Serum Levels of Soluble Triggering Receptor Expressed on Myeloid Cells-1 (sTREM-1) in Anti Neutrophil Cytoplasmic Antibody (ANCA)-Associated Vasculitis. Annals of the Rheumatic Diseases 2008. 67:723-4.
Gasser O., C. Berger, G. Zenhaeusern, H. Elsässer, I. Oehri, S. Schaub, C. Hess. Testing the 'Cytokine-ome' Theory: a Longitudinal Pilot Study in Renal Transplant-Recipients. Transplantation 2008. 85:491.
Eken C., O. Gasser, G. Zenhaeusern, I. Oehri, C. Hess, J.A. Schifferli. PMN-ectosomes interfere with the maturation of monocyte-derived dendritic cells. J. Immunol. 2008. 180:817-24.
Gasser O., M. Wolbers, I. Steffen, H.H. Hirsch, M. Battegay, C. Hess. Increased EBV-specific antibody-levels in HIV-infected individuals developing primary CNS lymphoma. AIDS 2007. 21:1664-6.
Gasser O., F. Bihl, M. Wolbers, E. Loggi, I. Steffen, H.H. Hirsch, H.F. Günthard, B.D. Walker, C. Brander, M. Battegay, C. Hess. HIV Patients Developing Primary CNS Lymphoma Lack EBV-specific CD4+ T Cell Function Irrespective of Absolute CD4+ T Cell-Counts. PLoS Med. 2007. 27:e96.
Zenhaueusern G., O. Gasser, L. Saleh, J. Villard, J.-M. Tiercy, C. Hess. Investigation of alloreactive NK cells in mixed lymphocyte reaction using paraformaldehyde-silenced target cells. J. Immunol. Meth. 2007. 10:196-9.
Gasser O., T.A. Schmid, G. Zenhaeusern, C. Hess. Cyclooxygenase regulates cell-surface expression of CXCR3/1-storing granules in human CD4+T cells. J. Immunol. 2006. 177:8806-12.
Friedrich E.B., Y.P. Clever, S. Wassmann, C. Hess, G. Nickenig. 17beta-Estradiol Inhibits Monocyte Adhesion via Down-Regulation of Rac1 GTPase. J. Mol. Cell. Cardiol. 2006. 40:87-95.
Islam S.A., S.Y. Thomas, C. Hess, B.D. Medoff, T.K. Means, C. Brander, C.M. Lilly, A.M. Tager, A.D. Luster. The Leukotriene B4 Lipid Chemoattractant Receptor BLT1 Defines Antigen-primed T-cells in Humans. Blood. 2006. 107:444-53.
Gasser O., A. Missiou, C. Eken, C. Hess. Human CD8 T cells store CXCR1 in a distinct intracellular compartment and up-regulate it rapidly to the cell-surface upon activation. Blood. 2005. 106:3718-24.
Woodberry T., T.J. Suscovich, L.M. Henry, M. August, M.T. Waring, A. Kaur, C. Hess, J.L. Kutok, J.C. Aster, F. Wang, D.T. Scadden, C. Brander. αEβ7 (CD103) Expression Identifies a Highly Active, Tonsil-Resident Effector-Memory CTL Population. J. Immunol. 2005. 175:4355-62.
Sadallah S., M. Heim, C. Hess, T. Klimkait, N. Doppler, M. Battegay, J.A. Schifferli. Contrary to HIV, hepatitis C virus is not associated with erythrocytes in vivo. J. Hepatol. 2005. 42:150-2.
Hess C., Means K.T., Autissier P., Woodberry T., Altfeld M., Addo M.M., Frahm N., Brander C., Walker B.D, Luster A.D. IL-8 responsiveness defines a subset of CD8 T cells poised to kill. Blood 2004. 104:3463-71.
Regamey N., V. Hess, J. Passweg, C. Hess, J. Steiger, P. Erb, G. Cathomas, M. Tamm. Infection with human herpesvirus 8 and transplant-associated gammopathy. Transplantation 2004. 77:1551-4.
Hess C., M. Altfeld, S.Y. Thomas, M.M. Addo, E.S. Rosenberg, T.M. Allen, R. Draenert, R.L. Eldridge, J.v. Lunzen, H.J. Stellbrink, B.D. Walker, A.D. Luster. HIV-1-specific CD8 T-cells with an effector-phenotype and control of viral replication. Lancet 2004. 363:863-6.
Thomas S.Y., T. Means, J. Gumperz, J. Boyson, C. Hess, H. Runhua, D.P. Olson, M. Brenner, S.B. Wilson, A.D. Luster. CD1d Restricted Invariant T Cells Express Receptors Consistent with Th1 Inflammatory Homing Cells. J. Immunol. 2003. 171: 2571-80.
Gasser O., C. Hess, S. Miot, C. Deon, J.C. Sanchez, J.A. Schifferli. Ectosomes released by human PMN are multi-functional vesicles that bind to phagocytic and endothelial cells. Exp. Cell Res. 2003. 285: 243-257.
Sadallah S., C. Hess, M. Trendelenburg, C. Vedeler, M. Lopez-Trascasa, J.A. Schifferli. Autoantibodies against complement receptor 1(CR1) in SLE, liver cirrhosis and HIV-infected patients. Clin. Exp. Immunol. 2003. 131: 174-81.
Hess C., Th. Klimkait, L. Schlapbach, V. Del-Zenero, S. Sadallah, G. Ballestra, V. Werder, C. Schaefer, M. Battegay, J.A. Schifferli. HIV-1 is associated with erythrocytes in vivo. Lancet 2002. 359: 2230-34.
Hess C., S. Sadallah, J.A. Schifferli. Induction of neutrophil responsiveness to myeloperoxidase antibodies by their exposure to supernatant of degranulated autologous neutrophils. Blood 2000. 15; 2822-7.
Sadallah S., C. Hess, S. Miot, O. Spertini, H. Lutz, J.A. Schifferli. Elastase and Metalloproteinase Activities Regulate Soluble Complement Receptor 1 Release Eur. J. Immunol. 1999. 29:3754-61.
Trendelenburg M, C. Hess, M. Kondo-Oestreicher, J.D. Tissot, P. Späth, J. A. Schifferli. Monomeric complement activating IgG paraproteins. J. Immunol. 1999. 163:6924-32.
Hess C., S. Sadallah, A. Hefti, R. Landmann, J.A. Schifferli. Ectosomes Released by Human Neutrophils are Specialized Functional Units. J. Immunol. 1999. 163:4564-73.
Reviews, Comments and Webinars
Hess C. Three brief thoughts on peer-review. Cell 2019. In Press.
Hess C. The power of description. Nature Reviews Immunology 2019. 19:475.
Bantug G.R., L. Galluzzi, G. Kroemer, C. Hess. The spectrum of T cell metabolism in health and disease. Nature Reviews Immunology 2018. 18:19-34.
Bantug G.R., C. Hess. The burgeoning world of immunometabolites – Th17 cells take center stage. Cell Metabolism 2017. 26:588-590.
Balmer M.L., C. Hess. Starving for survival – how catabolic metabolism fuels immune function. Current Opinion in Immunology 2017. 46:8-13.
Dimeloe S., A.-V. Burgener, J. Graehlert, C. Hess. T cell metabolism governing activation, proliferation and differentiation; a modular view. Immunology 2017. 150:35-44.
C. Hess, C. Kemper. Complement-mediated regulation of metabolism and basic cellular processes. Immunity 2016. 16:240-54.
Balmer M.L., C. Hess. Feeling worn out? – PGC1α to the rescue for dysfunctional mitochondria in T cell exhaustion. Immunity 2016. 16:.233-5.
C.T. Berger, C. Hess. Neglected for too long? – CD8+ Tregs release NOX2-loaded vesicles to inhibit CD4+ T cells. Journal of Clinical Investigation 2016. 126:1646-8.
Bantug G.R., C. Hess. Glycolysis and EZH2 boost T cell weaponry against tumors. Nature Immunology 2015. 17:41-2.
Donath M., C. Hess, E. Palmer. What is the role of autoimmunity in type 1 diabetes? – A clinical perspective. Diabetologica. 2014. 57:653-5.
Hess C., together withL. Lynch and N. Restifo. Immunometabolism. Cell Press Webinars 2017:
Hess C. together with J. Rathmell and R. Jones. Metabolic regulation of immunity: Exploring programs that drive immune development and function. AAAS Science Magazine 2016: http://webinars.sciencemag.org/webinar/archive/metabolic-regulation-immunity