Selected Publications
Barthlott, T., Handel, A.E., Teh, H.Y., Wirasinha, R.C., Hafen, K., Žuklys, S., Roch, B., Orkin, S.H., de Villartay,J-P., Daley, S.R., Holländer, G.A. (2021). Indispensable epigenetic control of thymic epithelial cell development and function by Polycomb Repressive Complex 2. Nat.Comm. in press
Baran-Gale, J., Morgan, M.D., Maio, S., Dhalla, F., Calvo-Asensio, I., Deadman, M.E., Handel, A.E., Maynard, A., Chen, S., Green, F., et al. (2020). Ageing compromises mouse thymus function and remodels epithelial cell differentiation. Elife 9:e56221
Dhalla, F., Baran-Gale, J., Maio, S., Chappell, L., Holländer, G.A., Ponting, C.P. (2020). Biologically indeterminate yet ordered promiscuous gene expression in single medullary thymic epithelial cells.EMBO J. 39:e101828.
Handel, A.E., Shikama-Dorn, N., Zhanybekova, S., Maio, S., Graedel, A.N., Žuklys, S., Ponting, C.P., Holländer, G.A. (2018). Comprehensively Profiling the Chromatin Architecture of Tissue Restricted Antigen Expression in Thymic Epithelial Cells Over Development. Front Immunol. 9:2120.
Žuklys, S., Handel, A.E., Zhanybekova, S., Govani, F., Keller, M., Maio, S., Mayer, C.E., Teh, H.Y., Hafen, K., Gallone, G., et al. (2016). Foxn1 regulates key target genes essential for T cell development in postnatal thymic epithelial cells. Nat. Immunol. (10):1206