Publications of Nicole Schaeren-Wiemers

The whole list of publications can be seen: https://pubmed.ncbi.nlm.nih.gov/?term=schaeren-wiemers+n&sort=date

Selected Publications

Enz, L.S.;Winkler, A.; Wrzos, C.; Dasen, B.; Nessler, S.; Stadelmann, C.; Schaeren-Wiemers, N. An Animal Model for Chronic Meningeal Inflammation and Inflammatory Demyelination of the Cerebral Cortex. Int J Mol Sci. 2023 Sep 9;24(18):13893. doi: 10.3390/ijms241813893. PMID: 37762198

Mert Duman, Stephanie Jaggi, Lukas Simon Enz , Claire Jacob and Nicole Schaeren-Wiemers. Theophylline Induces Remyelination and Functional Recovery in a Mouse Model of Peripheral Neuropathy Biomedicines. 2022 Jun 15;10(6):1418. doi: 10.3390/biomedicines10061418. PMID: 35740439

Duman M, Vaquié A, Nocera G, Heller M, Stumpe M, Siva Sankar D, Dengjel J, Meijer D, Yamaguchi T, Matthias P, Zeis T,Schaeren-Wiemers N, Hayoz A, Ruff S, Jacob C.. EEF1A1 deacetylation enables transcriptional activation of remyelination. (2020). Nat Commun. 2020 Jul 9;11(1):3420. doi: 10.1038/s41467-020-17243-z. PMID: 32647127

Jäckle K, Zeis T, Schaeren-Wiemers N, Junker A, van der Meer F, Kramann N, Stadelmann C, Brück W. Molecular signature of slowly expanding lesions in progressive multiple sclerosis. Brain. 2020 Jun 24:awaa158. doi: 10.1093/brain/awaa158. Epub ahead of print. PMID: 32577755.

Enz LS, Zeis T, Schmid D, Geier F, van der Meer F, Steiner G, Certa U, Binder TMC, Stadelmann C, Martin R, Schaeren-Wiemers N. (2020).  Increased HLA-DR expression and cortical demyelination in MS links with HLA-DR15. Neurol Neuroimmunol Neuroinflamm. 2019 Dec 27;7(2). pii: e656. doi: 10.1212/NXI.0000000000000656. Print 2020 Mar. PubMed PMID: 31882398.

Enz LS, Zeis T, Hauck A, Linington C, Schaeren-Wiemers N.  (2019) Combinatory Multifactor Treatment Effects on Primary Nanofiber Oligodendrocyte Cultures. Cells. 2019 Nov 12;8(11). pii: E1422. doi: 10.3390/cells8111422. PubMed PMID:31726669.

Faigle W, Cruciani C, Wolski W, Roschitzki B, Puthenparampil M, Tomas-Ojer P, Sellés-Moreno C, Zeis T, Jelcic I, Schaeren-Wiemers N, Sospedra M, Martin R. (2019) Brain Citrullination Patterns and T Cell Reactivity of Cerebrospinal Fluid-Derived CD4(+) T Cells in Multiple Sclerosis. Front Immunol. 2019 Apr 10;10:540. doi: 10.3389/fimmu.2019.00540. eCollection 2019. PubMed PMID:
31024521; PubMed Central PMCID: PMC6467957.

Elazar N, Vainshtein A, Golan N, Vijayaragavan B, Schaeren-Wiemers N, Eshed-Eisenbach Y, Peles E. (2018) Axoglial Adhesion by Cadm4 Regulates CNS Myelination. Neuron. 2019 Jan 16;101(2):224-231.e5. doi: 10.1016/j.neuron.2018.11.032. Epub 2018 Dec 11. PubMed PMID: 30551998; PubMed Central PMCID: PMC6371057.

Planas R, Santos R, Tomas-Ojer P, Cruciani C, Lutterotti A, Faigle W, Schaeren-Wiemers N, Espejo C, Eixarch H, Pinilla C, Martin R, Sospedra M. (2018). GDP-l-fucose synthase is a CD4(+) T cell-specific autoantigen in DRB3*02:02 patients with multiple sclerosis. Sci Transl Med. 2018 Oct 10;10(462). pii:eaat4301. doi: 10.1126/scitranslmed.aat4301. PubMed PMID: 30305453.

Zeis T, Howell OW, Reynolds R, Schaeren-Wiemers N. (2018). Molecular pathology of Multiple Sclerosis lesions reveals a heterogeneous expression pattern of genes involved in oligodendrogliogenesis. Exp Neurol.  Mar 26;305:76-88. doi: 10.1016/j.expneurol.2018.03.012.

Herrendorff R, Hänggi P, Pfister H, Yang F, Demeestere D, Hunziker F, Frey S, Schaeren-Wiemers N, Steck AJ, Ernst B. (2017). Selective in vivo removal of pathogenic anti-MAG autoantibodies, an antigen-specific treatment option for anti-MAG neuropathy. Proc Natl Acad Sci U S A. 2017 May 2;114(18):E3689-E3698. doi:10.1073/pnas.1619386114. Epub 2017 Apr 17. PubMed PMID: 28416698; PubMed Central PMCID: PMC5422814.

Zeis T, Enz L, Schaeren-Wiemers N. (2016). The immunomodulatory oligodendrocyte. Brain. Res. 2016 Jun 15;1641(Pt A):139–48. doi: 10.1016/j.brainres.2015.09.021.Epub 2015 Sep 28. Review. PubMed PMID: 26423932

Weil MT, Möbius W, Winkler A, Ruhwedel T, Wrzos C, Romanelli E, Bennett JL, Enz L, Goebels N, Nave KA, Kerschensteiner M, Schaeren-Wiemers N, Stadelmann C, Simons M. (2016). Loss of Myelin Basic Protein Function Triggers Myelin Breakdown in Models of Demyelinating Diseases. Cell Rep. 2016 Jul 12;16(2):314-22. doi:10.1016/j.celrep.2016.06.008. Epub 2016 Jun 23. PubMed PMID: 27346352; PubMedCentral PMCID: PMC4949381.

Lindner M, Thümmler K, Arthur A, Brunner S, Elliott C, McElroy D, Mohan H, Williams A, Edgar JM, Schuh C, Stadelmann C, Barnett SC, Lassmann H, Mücklisch S, Mudaliar M, Schaeren-Wiemers N, Meinl E, Linington C. (2015). Fibroblast growth factor signalling in multiple sclerosis: inhibition of myelination and induction of pro-inflammatory environment by FGF9. Brain. 138:1875-93. doi: 10.1093/brain/awv102.

Zeis T, Allaman I, Gentner M, Schroder K, Tschopp J, Magistretti PJ, Schaeren-Wiemers N. (2015). Metabolic gene expression changes in astrocytes in Multiple Sclerosis cerebral cortex are indicative of immune-mediated signaling. Brain Behav Immun. 48:313–25. doi:10.1016/j.bbi.2015.04.013

Schmid D, Zeis T, Sobrio M, Schaeren-Wiemers N. (2014). MAL overexpression leads to disturbed expression of genes that influence cytoskeletal organization and differentiation of Schwann cells. ASN Neuro 6:1759091414548916, first published on September 10,2014 doi:10.1177/1759091414548916

Schmid D, Zeis T, Schaeren-Wiemers N. (2014) Transcriptional regulation induced by cAMP elevation in mouse Schwann cells. ASN NEURO 6(3):art:e00142.doi:10.1042/ AN20130031